Mirtazapine for Major Depressive Disorder User Reviews (Page 5)

• Jim...
• Taken for 1 to 6 months
• April 1, 2021

"After more than 30 years of major depression and severe anxiety, I finally stumbled upon Remeron during my last stay in the psych ward, and it has been a game changer. I had been taking 200 mg amitriptyline per day and now am on 30-45 mg mirtazapine. (I'm a big guy and unfortunately getting bigger.) I'm also (previously) a long-term, professional alcoholic and have not touched a drop or even thought about it since my first dose of Remeron some months ago. I'm convinced that this medication has saved my life and would encourage anyone at the end of his or her rope to try it. Better yet, don't wait until crunch time and instead consider it as a second-line treatment if SSRIs or SNRIs don't work for you."

• Wea...
• Taken for less than 1 month
• August 5, 2020

"I started this mirtazapine medicine primarily for depression, which is so bad at the moment. I only stayed on it for about 7 days. The reasons were that it interfered with my DHC (opioid pain reliever), and thus I awoke every morning in far more pain than usual. I also read about bad nightmares with this medicine, but until about day 6, I never experienced them, however, on the sixth evening of taking them, I had the most incredibly real and horrifying nightmare I have ever had. I could not turn out the light for a long time. I also had some mild open-eye sort of hallucinations too, like seeing lights moving around my bedroom. And finally, the constant feelings of being really tired and exhausted all the time. It did take a little edge off the extreme feelings, but I was just too dopey all the time. I believe this medicine could help some people, but not for me."

• Bec...
• July 31, 2017

"I had been on quite a few SSRIs, and nothing helped my major depression and panic disorder. This was a last resort medication for me and ended up working like a dream. I was eased onto the meds slowly, which helped my doctor determine the correct dosage once I got used to it. I have experienced weight gain, but the weight gain does not increase with the dosage. Also, I've had some acne flare-ups. I take the medicine at night so the drowsiness doesn't ruin my day. The side effects are a small price to pay for the exchange of a happy life again! If you have had trouble with Prozac, Zoloft, etc., please ask your doctor to try this medication next! I wish I had found this years earlier!"

• Sle...
• February 16, 2016

Mirtazapine "The first night I took it, I slept for 16 hours straight (15 mgs). When I finally forced myself to get out of bed, I had this insatiable appetite. I also walked around like a zombie, feeling groggy for the next day and a half. I took it on a Saturday night, knowing that I didn't have to be anywhere the following day (good thing). Needless to say, I stopped taking it."

• mik...
• Taken for 1 to 6 months
• February 28, 2019

"Good for getting you to sleep at 15 mg, but the next day, horrendous depression, amplified ten times. My aggression increased too. Was on this two months, but had no effect on depression, not at all. All that it did the next day was make me want to curl up. Came off of it, feel a lot better."

• Meg...
• May 2, 2017

"I was put on 15 mg of Mirtazapine about a month ago, and it was the best decision ever. I've been very depressed and underweight (unintentionally due to stress and high metabolism) almost all my life. I went to my doctor at the end of my rope, having been off any type of anti-depressants, anti-anxiety, etc. for 5 years - I told him that all the previous SSRIs and SNRIs I'd been on hadn't worked because they made me both suicidal and lose more weight (I generally have a BMI of 15-17 max). He recommended this, and if it weren't for me giving medicinal treatment one more shot, I wouldn't be sleeping, eating, or in the process of finally getting my degree and my own place! The only downside was that in the first 2 weeks, I had some dry mouth/tiredness."

• Bub...
• May 20, 2016

"Post update from 3 weeks ago, I'm now 4 weeks in on 30 mg but have decided to taper off due to the weight gain and dizziness. I'm now 203 lbs after gaining another 8 pounds from increasing to 30 mg from 15 mg. In a total of 10 weeks from starting this medication from 7.5 mg, I gained 20 pounds and 3 inches on my waist. The side effects, unfortunately, outweigh the benefits. This medication just makes you want to eat anything in sight. I feel like a fat blob where 10 weeks ago I was somewhat fit. I can't control the carb and sugar cravings. Onto the next med, I guess!"

• Not...
• Taken for 6 months to 1 year
• December 2, 2020

Mirtazapine "I took Remeron for 6 months. It did wonders for my depression and anxiety during the first weeks. I started with the 15mg dose, but as time passed, the effect started to disappear. I increased my dose to 30. The same thing happened, the effect disappeared. Now I am taking 45mg, and the effect is not at all the same as I felt in the first weeks. Unfortunately, this medicine is not a long-term medicine. I am thinking of changing."

• Lil...
• Taken for 1 to 6 months
• January 7, 2022

Mirtazapine "This medicine completely wipes me out. All it does is make me sleep. I can sleep over 24 hours straight when I take this. Does nothing for depression because it makes me sleepy and can’t do anything anyway when you’re sleepy."

• Han...
• Taken for 1 to 6 months
• February 26, 2021

"I've been dealing with chronic depression my whole life with terrible anxiety. Tried all kinds of antidepressants over the years, and this drug is a Godsend. I've never liked most antidepressants due to the negative effects on sex drive, and this hasn't messed with my sex life one bit. Made me extremely groggy/sluggish with crazy hunger at first, but after a month or two of taking it, all bad side effects went away. Doesn't make me feel like an emotionless zombie like most other antidepressants. Went from having panic attacks every day to one every two weeks, maybe. I'm the happiest I've been in years. Only been taking it for about 4/5 months as well."

• JWi...
• July 6, 2016

"Started 7.5 mg of Mirtazapine on June 3rd for anxiety and depression. My episode started in the beginning of May, and I was having good days and bad days. After starting the Mirtazapine, I still feel general sadness and not myself. I had moments of clarity but just wasn't feeling enough effect. After three weeks, I upped my dose to 15 mg. I immediately felt better and like my old self. I was so excited, but that only lasted for a week. The last two days, the depression/sadness has crept back in along with the worrying. I called the doc to see about upping my dosage to 30 mg. She wants me to give it another week and then go back and talk about upping the dosage or trying a different med. I can't do SSRIs, they sent me off the deep edge."

• Nat...
• Taken for 1 to 6 months
• December 29, 2015

"My daughter is 12. She has been taking mirtazapine for a good 2 months because she could not sleep and had depression. It is the best for her, she can sleep, and the depression is getting better. I hope it keeps working."

• Yan...
• Taken for less than 1 month
• April 8, 2020

"I took this medication, mirtazapine, for about a week for major depressive disorder. It made me EXTREMELY tired and foggy. I could barely do anything except sleep the entire time I was on it. The doctor said it would pass, but I couldn't wait for that to happen because I had to have the energy to go to work every day."

• Rox...
• Taken for 6 months to 1 year
• January 11, 2022

"I have been taking mirtazapine for 8 months at 15 mg. I had major depression with anxiety, panic attacks, and insomnia. I was struggling to work as the lack of sleep made me feel ill at work and often faint. After 1 month of taking them, my panic attacks stopped, and I slept. I have, however, reduced them to 7.5 mg as I had issues waking up in the morning with a bad headache and feel a lot better now. I am also able to work. So, a really good antidepressant for insomnia and panic attacks. However, I have put on some weight, but it’s worth it for the positive benefits it gives."

• 170...
• Taken for less than 1 month
• April 2, 2019

"I was on an SSRI for 2.5 years to treat depression and anxiety. The SSRI worked for a couple of months until my life took on more responsibility. I started to feel depressed and anxious again. One major side effect of the SSRI was a significant reduction in sex drive. Being a male, that lowered my confidence even more. I've been on mirtazapine for 2 weeks now, still early days. However, since being on it, I immediately experienced improvements. My sex drive has returned to normal, I sleep much better, and I am more excited about life in general. The only real side effect I've experienced is dizziness on a daily basis. Hopefully this will go away in a few weeks."

• Ech...
• Taken for less than 1 month
• August 27, 2018

"I was referred to this medication due to my depression and insomnia, it left a horrible taste in my mouth all day. For sleep, it did help me sleep, however, I experienced the feeling other people on here have described as a foggy feeling all day, forgetfulness, and just a ‘zoned out’ feeling. The big thing for me I felt with this medication was the dark thoughts. I’m an ex-self harmer. I felt awful, thoughts of deep negativity and wanting to hurt myself. So for me, I’ve stopped this medication in under a month of taking it. However, every individual is different and will have their own experience. But for me, it was a no go."

• Ble...
• Taken for 1 to 6 months
• May 2, 2016

"Have had a good experience overall with this medication, with an improvement in general symptoms (major depressive disorder). Although I have had nightmares, passing peripheral edema, plus an unexplained 10-point increase in blood pressure as side effects. These have been much less and more tolerable than the side effects of the other medications I have used, as listed next. I have also used Cymbalta, Effexor, Allegron, and Valdoxin (in order of my opinion of their effectiveness) with Cymbalta/Valdoxin in combination for a period (over 18 months). I have also undergone ECT. If I had this information when I started, I would have chosen this medication as a starting point."

• Sna...
• November 4, 2019

"I used to have bad panic attacks and found it really hard to sleep before I was prescribed mirtazapine. The first few weeks of getting used to it were awful. I often felt dizzy and nauseated 10 minutes after taking it and collapsed once, luckily, a family member was there, and I was carried to my bed. After that passed, it worked amazingly for me. I haven't had a panic attack since having it, and I've found it a lot easier to sleep. I feel more calm and less paranoid than I used to. I went from a size 4 to a size 8/10, and it's been rough trying to lose the weight. I have only started taking control of it now. It gave me a huge appetite at the beginning, and I was constantly hungry. I've also noticed that I'm a lot more tired lately and have a lot less energy than I used to. Sometimes I also find it a little difficult to sleep. Another odd thing I have noticed: I dream almost every night and remember all of them. They are usually odd dreams, although I've gotten sleep paralysis a few times (I have a history of them)."

• Ell...
• Taken for 2 to 5 years
• July 24, 2019

"I was put on 30 mg at bedtime for MDD and anxiety disorder. I was so relieved that I could finally relax at night without benzodiazepines, but I gained 50 pounds (100 initially, but lost 50 due to lowering the dosage of another medication and drinking water instead of sweet tea). Now I take 45 mg, the maximum dosage, half before bed and half in the middle of the night. I sometimes want to take it for anxiety during the day, but I'm already at maximum dosage. I don't think I'll ever be able to get off this medication, but I really want to lose the extra 50 lbs. It is supposedly not addictive, but I couldn't get off of it on my own. I'm definitely dependent on it, but it does relieve my anxiety and helps me sleep. You just have to resist the sugar cravings, especially at bedtime!"

• Joh...
• Taken for less than 1 month
• July 9, 2019

"I was diagnosed with major depression and anxiety. It's my first time dealing with meds at the age of 23. I am happy and terrified because my appetite is back tenfold, and I am scared that I am going to balloon in my weight. I am taking 15 mg of mirtazapine once per night for full disclosure to you guys. Before, I felt like there was a demon inside me that was causing me to drown in feelings of guilt and awfulness many times a day. This medicine is keeping the demon locked in his cage, but some days it feels like nothing is happening at all. I still have an irregular pattern of sleep that will keep me awake in my own mind until 3-6 a.m. My doctor told me that the people around me will notice the effects before I do. Even though my feelings of anxiety are being repressed, I am still biting my nails so hard until they bleed. I don't even realize I'm doing it anymore."

• Raz...
• Taken for 1 to 6 months
• August 27, 2019

"Doctor started me on 15 mg mirtazapine for my depression and insomnia. I've been on the tablet for several weeks now and have experienced really bad nightmares and always wake up with a dry mouth. The tablet has helped me sleep, I start to feel sleepy 30-45 mins after taking it but have had really bad nightmares where I'm trying to find a way to escape 'cause I'm ready to die with my family and friends or whoever is in my dream. But then I wake up all of a sudden. I'm thinking of changing my tablet as it seems a bit too strong for me. Have started to binge eat, putting on the kgs."

• Lis...
• Taken for 1 to 6 months
• August 11, 2021

"I was diagnosed with bipolar II this year. I'm a 41-year-old female. What led to my diagnosis was that I had become overwhelmingly fatigued and also had panic problems, I felt like I was dying. But the doctors all said it was 'just anxiety.' What it was, was hypomania. The fatigue and all the other body symptoms were from not really sleeping. Once I got diagnosed, I took lithium and Remeron. I felt better almost immediately. The Remeron helped me sleep right away at 7.5 mg for the first week. I had no side effects. I take 15 mg every night, and it's my 3rd month on it. I get the munchies very badly at bedtime, and I have gained weight in the middle. I sleep easily for 10 straight hours. But it's worth it, I feel, because I am not having major depression, physical symptoms of PTSD or fatigue, and I sleep well. All the terrible symptoms I was experiencing because of fatigue and mania are gone. The Remeron is prescribed to me to help with depressive episodes and also to help me sleep when I'm manic. It's done great at both."

• Ren...
• Taken for 1 to 6 months
• May 15, 2020

Mirtazapine "I started on this drug, Remeron, at 15 mg, found that it worked for two weeks, then the anxiety came back, so I upped it to 30, and guess what, the same thing happened, so I’m trying 37.5. I hope these meds begin to work and stay that way."

• Wil...
• Taken for 1 to 6 months
• October 26, 2020

"Mirtazapine didn't help my MDD much. I've been on Seroxat, Prozac, and about 3 or 4 others over the years. There's always something not right. With these, I wanted something for sleep, but they just made me drowsy and so hungry, so I've put on loads of weight, which is really bad for me as I have food-related MH issues/ED. I'm not sure what else to do, but no doubt they'll give me something else, and the circle goes round again. I have to have other ways to help my issues... if help is the right word."

• Deu...
• May 10, 2020

"I've been on mirtazapine 45 mg for about 30 years. For the first 20 years, everything went as expected, in that it mitigated my MDD, and I consistently slept through the night. Then, about 10 years ago, I got my first bottle of 'blanks,' pills that I feel do not contain the drug or only a minute amount. Such bottles started coming my way with increasing frequency until it reached the point where I switched to the name brand Remeron, even though I would be forced to use the soltabs and they would cost slightly more than $5 a pill. You don't sleep, at least not so it does you much good. The last box was a mix of inert and at most 10% of the drug specified. I could tell by the taste of the first sol tab. Mirtazapine is QUITE bitter. This was as sweet as the sol tab sample the company reps hand out to doctors so they'll be able to tell patients that it's all right. I am in the third week of withdrawal and have been only able to snatch a couple of hours a night."