Mirtazapine for Major Depressive Disorder User Reviews (Page 2)

• Lau...
• Taken for less than 1 month
• February 25, 2022

"I've been Googling for weeks. They've been sitting in the kitchen. My anxiety and depression got bad, I couldn't even care for my kids, stopped leaving the house. I have health anxiety also, I Google everything, then feel 100 times worse. But last week, I just thought, what have I got to lose, and took 15 mg of mirtazapine. Woke up, felt a bit tired, but once up was okay. I didn't feel sad. I managed to clean the bathroom and do the kitchen, which is something I couldn't do before. When I'm talking about something now, I feel like I am in control, no crazy thoughts like I need to get out of here or I'm freaking out about stupid things, making myself worse. I was just getting out of control. Now I seem to think positively, and I'm not in sheer panic over stupid things. It got to a point I was checking my pulse, taking blood sugars, thinking I was ill. Remember, the mind is a very powerful thing. I never thought I'd ever take tablets because I'm scared of everything, but I'm so glad I did."

• Fre...
• Taken for 6 months to 1 year
• September 21, 2019

Mirtazapine "I have been giving Remeron to my wife (79), who has been diagnosed with advanced dementia. She sometimes is completely confused and becomes even hostile towards me, her husband of 50 years. I have experimented with various doses of Remeron and found out that giving her 15 mg doses three times a day is effective and usually keeps her in a reasonable to good mood. In the evening, her anxiety comes back about our cats who are used to going outside. I give her a small alcoholic drink (Irish Cream), which has a very beneficial effect on her. Remeron does not seem to interact negatively with alcohol. One hour before bedtime, I give her 10 mg of Melatonin. She sleeps very well. I have found that 15 mg of Remeron in the morning, 15 to 30 mg at 2 pm, and sometimes another 15 mg in the evening is a very good combination. I know that one should not give more than 45 mg a day, but sometimes an additional dose at night is necessary."

• LJM...
• Taken for 5 to 10 years
• May 25, 2024

"Mirtazapine is an underrated medication for mood & anxiety disorders, perhaps due to it being used at insufficient doses. The 30mg dose has worked well for me for many years now. Side effects are mild, with an increased appetite an hour or so after taking the tablet and a dry mouth in the morning being the only two I've experienced."

• LMF...
• Taken for 6 months to 1 year
• April 17, 2014

"I find this medication amazing! I can sleep really well on it although I have quite epic dreams which I remember when I wake up. Mirtazapine makes me feel peaceful and calm. I feel in control, less panicked and with the added bonus of sleep, I feel my overall mental health is improving. My appetite has increased but I have been told that it will stabilize after 12 weeks. I have no loss of sexual function and feel more in tune with myself than ever before. I am being observed for bipolar and mood disorders. This medication is a godsend to me. Only thing I can say is if you need to be up early take it 10/12 hours before you need to get up, I take it between 7 and 8pm and get up fresh at 7am."

• Ben...
• Taken for 1 to 6 months
• July 22, 2023

"I was in a very deep depressive hole due to a combination of awful events that I was going through. I tried escitalopram (which kinda worked for a while, but with severe sexual side effects) and venlafaxine (it didn't help at all). Then my doctor put me on 30mg of Mirtazapine and in two weeks, I felt alive again. It didn't make me happy or euphoric, but it took me away from that hole, and now it literally blocks any depression that may come from life's occasional misfortunes. The only side effect is that it increases my appetite, which in my case is helpful since I'm pretty skinny. The only downside is that it's a bit more expensive than other antidepressants, but I don't really mind. It's the best medication I've ever taken. Solid medication overall."

• kak...
• April 12, 2020

"Mirtazapine has proved to be a sanjivini (life saver) for me. Tired of almost all antidepressants and lost all hope. For a year, I had been in a pathetic condition and had major depression with many symptoms like hot flashes and suicidal thoughts. Tried this medicine, and after a few days, I was completely recovered. I would recommend it only if you have tried a few first-line treatments, as I had. It did increase my blood glucose level. I would suggest to all readers, please do not lose your hopes, as one or another medicine will help you sooner or later. God bless us all."

• Tk4...
• Taken for 2 to 5 years
• February 23, 2024

Mirtazapine "Remeron has helped me greatly with my anxiety and intrusive thoughts. My anxiety was so bad that I couldn’t eat or concentrate. Once I started taking Remeron, my sleep improved, my mood improved, and my appetite is back. I would highly suggest giving Remeron a try. Only downside for me personally is the weight gain. The cravings on this medication are very hard to control at times, especially at night."

• MAR...
• Taken for 6 months to 1 year
• May 21, 2025

Mirtazapine "I took this medication for 6 months. It did not help with my depression, but my depression is very drug-resistant and ended up having ECT. The medicine made me sleep constantly at first. That got better. What did not get better was the 24 hours of being hungry. I gained 100 pounds and became diabetic. I should have been taken off the medicine when the doctor saw how much weight I was gaining. Instead, I had to beg him to take me off of it, and now I have to take diabetes medicine for the rest of my life. If you are going to try this medication, I would recommend stopping it if your appetite does not get under control."

• Swe...
• January 17, 2016

Mirtazapine "My experience with Remeron is short. It worked wonders for me, but I stopped it as it causes awful weight gain. 21 pounds in 4 weeks. I looked pregnant. It made me more depressed. I would just eat. It does something to your brain that makes you feel as though you are never full. At night, I would sneak food. I could not stop. I was at 30mg. I've heard 15 mg is worse for weight gain. Also, this drug is also given to elderly patients who are undergoing chemotherapy and also given to people with eating disorders (bulimia and anorexia). As I said, in one respect, it did wonders for me with anxiety and depression and stopped the voices in my head and helped me sleep. But I couldn't go through gaining any more weight."

• Loe...
• April 2, 2020

"Mirtazapine was a godsend to me. I had tried all the antidepressants without success. I had given up when I was having a very difficult time maintaining housing, caring for my mother who has dementia, and losing my daughter and grandkids to Canada, where I can't afford to visit. My world was falling apart, and the depression was very serious. My psychiatrist prescribed Remeron (mirtazapine), and in a day or two, I saw the world in a completely hopeful way, where before mirtazapine, I believed life wasn't worth it anymore but couldn't do that to my sweet little girl. My only child. My only side effect was enjoying food! I gained 25 pounds, but I could use them. I had no appetite at all before."

• sam...
• August 19, 2014

"Once I got over the initial cravings and grogginess (they both passed after a few weeks) it was like a dark cloud was lifted, and I could finally see clearly - completely without the classic numbness and lack of personality that other common antidepressants have. Absolute life-changer."

• arn...
• Taken for less than 1 month
• May 11, 2017

Mirtazapine "I have been anxious, paranoid, and depressed since puberty (10 years). Doctors have tried SSRIs, SNRIs, and benzos, but nothing seemed to be working. The doctor wrote a script for Remeron. I was skeptical at first, and the initial side effects scared me (slurred speech, drowsiness, blurred vision), however, I kept with it and I feel so much better. It is relieving being able to live without thinking I am about to get fired or if I am getting fat (which is ridiculous). I actually have an eating disorder, and I am clinically underweight. My neurotic paranoia seems to be somewhat cornered, and I no longer depend on alcohol to keep me under control. I have only been on the drug for a week at 15 mg. Hopefully, this journey is almost over."

• Roc...
• Taken for 1 to 2 years
• October 19, 2022

"For me, mirtazapine has been a miracle drug! I’m not exaggerating. I have major depressive disorder and have been taking antidepressants since I was 11. I’m 32 years old currently. None of the SSRIs on the market have ever helped me. SNRIs don’t help either. It’s like swallowing a Tic Tac and expecting medical results. Mirtazapine has given me my life. It’s given me hope for the future. My depression has gotten worse with age. I developed psychosis with the depression in my late 20s. The doctor who put me on mirtazapine did so during a major depressive episode with psychosis. I was out of work and didn’t expect any results from this drug. I rolled my eyes thinking, okay, great! Another stupid pill. I saw results almost instantly. I slowly started coming out of the fog. Within two weeks, I was back at work. I’ve been on it for a couple of years and have not experienced depression since starting the med. I don’t plan to ever stop taking it."

• All...
• June 21, 2017

Mirtazapine "I have taken Remeron for over 6 years at 30 mg before bedtime to treat lifelong suicidal depression and debilitating social anxiety. In the first few days of taking it, I can say it was like a switch put to normal. It knocks me out within half an hour of taking it, and it is not possible to wake me into a coherent and alert state for at least 5 hours. That isn't an issue for me, and the family is used to it now also. The hours of guaranteed sleep are an added bonus. I have my life back, I no longer have social anxiety, and I can deal with very high-pressure situations perfectly fine. I have noticed a worsening of short-term memory issues, but given my line of work, I can't say it has a relationship to the med, and I will not go off the med to find out."

• G-D...
• Taken for less than 1 month
• August 20, 2017

Mirtazapine "This medicine is a godsend. Being 100% honest, I didn't like it because of the vivid nightmares, but they do stop with continued usage. Don't give up too soon. The vivid nightmares stopped after my 5th day of taking this drug. Now, 2 weeks later, my nightmares are gone and I have normal dreams that don't involve death, violence, or carnage. I sleep well and awaken rested. Some days there is a little grogginess in the morning, but it wears off as you start moving. A cup of coffee helps as well. My appetite has increased, and several people complain of weight gain. You will gain too much weight if you stay sedentary. I started lifting weights and doing planks and push-ups. That keeps the weight gain at bay."

• Tri...
• October 21, 2016

"I have been on Mirtazapine for 2 months now. I have a history of major depression, suicidal behavior, and anxiety. I was on Sertraline (Zoloft) for 1 year but discontinued after I felt 'better.' 6 months later, in April this year, I relapsed. But Sertraline didn't work, and I needed a new antidepressant. Mirtazapine helped with my sleep from the first night I took it. Within a week, my mood was much better. 2 months on, and I am elated, sleeping better, and in general, feel amazing. And this is only on a 15 mg dose! My appetite has also improved, and the only side effect I have been having with Mirtazapine is drowsiness, which was a benefit in my eyes, as it helps me fall asleep. No more insomnia, no more depression, and no more anxiety!"

• med...
• September 7, 2018

Mirtazapine "I have taken this med for over 2 years. I've been suffering from insomnia, anxiety, and depression my whole life. I found that nothing could help. Every night I tossed and turned, waking up every 2 hours. The first night I took this, like magic, I slept a whole night without waking up. And every night since then it has worked. However, BEWARE, it will make you binge eat. You have NO control over it. Studies say weight gain from this med only affects like 15% of people. Use look at the reviews on here and across the internet–it's more like 90%. I've always been skinny, and I put on 14 pounds within a month of starting it. I quit for a week, which made me extremely depressed and unable to sleep, but I immediately lost all the weight. But I was so depressed, it hurt, so I got back on it. That's why I give this a 7, it's a conundrum, it helps so much with insomnia/depression/anxiety, but it makes you FAT. Don't try this med unless you've tried ALL other SSRIs and sleep meds."

• Sar...
• Taken for 1 to 6 months
• February 17, 2017

"I've been on Cymbalta, Effexor, Trintellix, and Prozac. Prozac was good, but Remeron/mirtazapine works better for anxiety by far! I started suffering from anxiety when I was 12, and Remeron/mirtazapine has given me 'wings to fly.' I can drive relaxed, and I don't ruminate over things and make myself sick with worry, so in turn, my depression eases up because I'm not consumed with dread. The only downside is I feel hungry ALL the time, but I use willpower. For snacking, I cut up celery and carrots and drink cold green tea instead of eating anything and everything because if you're not watchful, I guarantee you'll put on a lot of weight. I basically had to get used to being hungry. All the best."

• fai...
• November 18, 2015

Mirtazapine "Just started taking this med again. I've been on more than I can count over the years. The only downfall I've had is the daytime foggy feeling which I'm hoping will subside over time. I've only been taking this less than a week and my depression symptoms have greatly improved as well as I sleep well every night. Appetite has gone up for me as well but not a concern for me at this point. Very happy overall. I will post again in a few weeks to give another update"

• Lov...
• April 26, 2021

Mirtazapine "I was taking this medication for six years, and it was life-changing. I was struggling to gain weight, I never had an appetite, and I was depressed, and no medication seemed to work, but Remeron was the only pill that worked for me. Unfortunately, I put on 40 pounds, and I have an almost overweight BMI, so I will have to stop this medication. This medication won't 'cure' your depression, but it's as if nothing seems like a big deal when you're on it, so therefore you feel less stressed and anxious."

• JeN...
• Taken for less than 1 month
• January 8, 2023

Mirtazapine "I am an addict. I started taking Remeron at Recovery Works about 4 weeks ago. I have always had trouble sleeping due to many, many years of drug use, so they started me on 15 mg. It wasn't working, so my dosage was increased to 30 mg. Within 20 minutes after taking it, I am ready for bed. I still wake up 1-2 times every night, but I have had no trouble falling asleep whatsoever. Also, my craving to use has dramatically decreased. I don't feel like I am dependent on it, but I definitely want to take it every night before bed. My appetite and weight have remained under control and normal. I do feel a little 'foggy' in the mornings, but it usually subsides, and I am not drowsy or tired throughout the next day. This drug was the answer to my insomnia. Definitely a plus for people in recovery."

• cjo...
• Taken for 1 to 6 months
• April 6, 2015

Mirtazapine "No matter how much sleep I got, I was constantly tired. I could barely function during the day. And when I was functioning, I wanted to eat everything. In 2 months, I ended up gaining 15 lbs, which definitely did not help with the depression."

• Ano...
• Taken for 2 to 5 years
• August 30, 2017

Mirtazapine "I have been taking Remeron for about three years, at various dosages. It does a great job of handling my depression without aggravating my anxiety. It also gives me severe munchies, especially for carbs. But otherwise, I have no side effects. Which is a first with me and antidepressants; the SSRIs in particular wrecked me. My doctor told me that usually, people who can't take SSRIs will be able to tolerate Remeron."

• Joh...
• Taken for 1 to 6 months
• January 24, 2015

"I've had major depression mostly every day for the last 2 years, and this medication is a lifesaver. After being on mostly every SSRI and on several different dosages, I never got complete relief from them. They helped to give me a slightly better mood on most days, but the depression was always there. After doing a lot of research, I told my psychiatrist I wanted to try mirtazapine. After roughly two and a half weeks on 30 mg (15 mg didn't help), I've never felt better. It also took away most of the night sweats that I was getting from SSRIs. I've read some people complaining about weight gain as a side effect, I would advise not to worry about weight gain if you actually have major depression. Once the depression lifts, you will be able to eat healthy."

• Mag...
• December 30, 2015

"Normally, antidepressants work on me within a few days to a week if they are going to work at all. Not so with mirtazapine! It took about 4 weeks to work, and when it did, it improved my depression and anxiety symptoms more than any other antidepressant/antianxiety drug I have ever taken (Lexapro, Wellbutrin, Cymbalta, Effexor, Klonopin). I am glad I didn't give up on it after a short time, for I never would have discovered how well it worked for me!"