Mirtazapine for Major Depressive Disorder User Reviews (Page 3)

• Mag...
• December 30, 2015

"Normally, antidepressants work on me within a few days to a week if they are going to work at all. Not so with mirtazapine! It took about 4 weeks to work, and when it did, it improved my depression and anxiety symptoms more than any other antidepressant/antianxiety drug I have ever taken (Lexapro, Wellbutrin, Cymbalta, Effexor, Klonopin). I am glad I didn't give up on it after a short time, for I never would have discovered how well it worked for me!"

• NY ...
• Taken for 1 to 2 years
• December 3, 2014

Mirtazapine "I have often extremely severe chronic depression/anxiety and Crohn's disease. My Crohn's disease can give me a great deal of acid reflux, so much so that I now have a hiatal hernia. Remeron did wonders for not only my MDD mixed with an SSRI (Prozac, Paxil, Wellbutrin, etc.), but it also settled my stomach and helped me sleep a bit better. It doesn't work very well any longer for sleep. I tried getting off it at one point, and I went totally mental! It was only initially making me constipated for the first month, but it helps me hang on somehow."

• Tai...
• Taken for 1 to 2 years
• October 15, 2020

Mirtazapine "I have suffered from major depression for the past 20 years, which caused severe insomnia. Remeron has been a lifesaver. I have been able to sleep, but it causes weight gain. My doctor decreased it from 45 mg to 30 mg. There is no major difference between the dosages. I will be following a diet suggested by my dietician to lose 7 pounds gained from the meds."

• Ali...
• December 16, 2020

"I wanted to share my experience because I have been an avid review reader and often only negative experiences are shared. I tried Zoloft, Prozac, Wellbutrin, and Lamictal, and the side effects from all of these were too much for me. Remeron helps me sleep and gives me a feeling of general wellness and an ability to cope. It takes away that crushing depression that tells you you aren’t good enough and doesn’t allow you to get out of bed. The big story on this drug is about the weight, and I want to share with you that I may be a pound or two heavier with this drug than without it, but this drug actually helps me eat less. I used to feel hungry all the time and wake up at night from hunger, but now I can sleep through. Take the lowest dose you can if you are worried about this side effect and know that not all people gain weight on this drug."

• Pin...
• Taken for 1 to 2 years
• June 11, 2021

"When Escitalopram 20+10=30 mg failed to cope with MDD after 9 years, then also failed trazodone, desvenlafaxine... but Mirtazapine 15 mg saved me. It's a lifesaver for me. Now I'm taking escitalopram 20+10 mg with Mirtazapine 15 mg and Lithium carbonate 400 mg. Suicidal thoughts are gone. Love you, Remeron. In treatment-resistant depression, Mirtazapine showed wonders. Please don’t stop your drug after showing negative reviews. Remember, all antidepressants are different. I didn't have any weight gain, make sure you have a healthy diet."

• Mam...
• Taken for less than 1 month
• May 22, 2016

"I have fallen in love with this med! My cyclic depression was at an all-time high, suicidal ideation, hopelessness, severe anxiety and paranoia, insomnia, and ready to literally give up on life. I started on 15 mg for the first 2 days. It knocked me out, and I slept very well. Bad side effect was being super groggy all day long and a little foggy. Not a big change in depression until the third or fourth day. I upped the dosage to 30 mg on the third day, and after a week, I am feeling so much better! It doesn't completely knock me out right away like the first night but just makes me a little tired. I wake up ready to face the day and happy. The dreams are a little crazy, but they're kind of just like fun adventures. I recommend this drug!"

• Mar...
• Taken for 1 to 6 months
• January 7, 2022

Mirtazapine "I was in another deep, dark place. Have been on Lexapro for years because I struggle with MDD. It seems the Lex doesn't help much like it used to. When I go downhill, my stomach is affected. I lose my appetite and can barely eat. I get these gnawing hunger pains and eat to get rid of them, but then shortly after, I'm hungry again, but nothing sounds good or tastes good. I'm afraid of trying new meds. It's so hard. So many don't help, and you have to be on them for quite a while to know if they work. I've tried several in the past, and they gave me chest pressure/pain. Unusual, but it happens. Didn't want to try Remeron, but I was desperate. God heard my many prayers and many who were praying for me! Started feeling better and eating normally within a week! Crazy dreams and shaky for a while, but that got better. Also, am gaining weight back that I lost."

• Rem...
• Taken for 6 months to 1 year
• November 25, 2017

Mirtazapine "I have had several bouts of depression in the last 30 years. SSRIs don't work for me. Tried them all. Remeron was a lifesaver. Started at 15 mgs and now up to 45 mgs. Didn't sleep well before this med. It cured my depression, anxiety, and insomnia. Only con is weight gain, which I'm working on with walking and eating a healthy diet. My husband said he'd rather see me chubby and happy, and I totally agree. I'm so glad my doctor put me on this tricyclic antidepressant."

• Kiw...
• Taken for 10 years or more
• December 14, 2019

"I have struggled with depression all my life, and mirtazapine is one of the few medications that seems to level me out and make life a little bit more bearable. I started on 15 mg probably about ten years ago and quickly went to 30 mg, which made a big difference. If you suffer from severe depression like me, I truly believe the dosage is crucial. Eventually, I increased to 45 mg recently, but after being on 30 mg for several years, the extra 15 mg seemed to reignite my urge to eat everything in sight, which I don’t like, as you just end up overeating. But overall, once you get used to the dosage you have been prescribed, you can generally control the food cravings, but if you increase the dosage, the cravings will increase. Still, I would rate this drug much higher than other meds, as it doesn’t interfere with your libido like the others!"

• Sen...
• Taken for 1 to 6 months
• August 20, 2024

"The combination of 30 mg Mirt and 10 mg Trintellix saved my life. I attempted suicide while on Sertraline (had helped me in past MDD), and doctors and psychiatrists at the hospital changed my medication to the above combo. It really has worked wonders. I don't feel suicidal, I no longer dread getting out of bed wishing I didn't wake up, no more blackness, and I feel like I have now got control of my life again. It's 5 weeks into the combo, and while I am not fully recovered, this combination has really helped me think positively about the future again, and I can focus on my family and getting back to my old self."

• Jam...
• Taken for 2 to 5 years
• September 12, 2015

"Found this to be the best medicine for depression. I was treated with lots of different medications before I was put on 15 mg of mirtazapine. Now I'm on 45 mg due to the level of depression I have. I would recommend this to anyone with severe depression."

• MrL...
• Taken for 2 to 5 years
• September 7, 2019

"Works well for depression and helps me sleep. Also makes food utterly delicious! So be careful out there. Been taking 30 mg for about three years. Good luck. Hope this medicine works for you. Always have the attitude that this drug will help me when you start on something new."

• Dpl...
• Taken for 1 to 6 months
• August 31, 2023

"Life changing, been a chronic insomnia for over 20 years. Now I can finally sleep. I've been on 15mg for over 6 weeks now and my sleep is amazing, around 8 hours. Normally, I was lucky if I could get 5 or 6 hours. I've tried everything, spent thousands, tried every recommended potion, and so on. Mirtz is life-changing. Luckily, I am supplementing with Ozempic, a weight loss injection which I get privately, which stops any hunger on Mirtz. I tried Mirtz last year and had to stop after 5 days because I was eating 5000 calories a day and gaining fat rapidly. So I am experimenting with Ozempic for over a month now and it's working perfectly. I haven't experienced any side effects from either Mirtz or Ozempic. Life-changing stuff, guys. This is worth a million pounds to feel like this. No money or anything in the world can compare to sleeping well."

• Anonymous
• Taken for 1 to 2 years
• October 10, 2015

"Been on it for 1.5 years now. 45 mg at bedtime. Before taking it, I couldn't sleep, massive mood swings, bad anxiety. Had trouble being in crowds or around people. Since taking, been good, able to deal with whatever comes up in life. I sleep 8 hours a night. Takes a bit to wake up, but once awake, I'm good all day. Downside, don't miss more than two days of it, or I don't sleep, and everything goes into hyperdrive. I function very well on it, and it keeps me a lot more stable."

• Man...
• Taken for 1 to 6 months
• October 19, 2020

Mirtazapine "I have MDD, and my anxiety used to be really bad. The first week I took Remeron, I was knocked out on the first night and really groggy in the morning, and I remember being really hungry. I used to have a problem with my appetite, and I could never finish my food. I was at least 42 kg. But now I can finish my food, my appetite is really good, and I get enough sleep! Dreams are kind of weird, though. I read some bad reviews, but my experience has been great, and I’m on my 13th week, and the dosage is 30 mg. Just give it a few more weeks, and everything starts to get okay, and moods will start regulating like normal. If anyone else is taking this, do know that your appetite will increase, so get more exercise and watch what you eat!"

• Roc...
• Taken for 1 to 6 months
• July 9, 2018

Mirtazapine "I've been on Remeron and Abilify for a month now, and I can say it is true to what the doctor says it is. I paid $8 a piece for them both, at my insurance's expense. When I first started, the first two days were horrible. I was drained and hungry as heck, but my body adapted quickly. I lost 25 lbs before taking Remeron, and so far my weight has increased by 5 to 6 lbs. I have nightmares almost every night and mood swings when I don't eat, but that's just the downside. Overall, the medicine helps me sleep, eat, and feel better. I just have to get my rump back into the act of working out to avoid weight. Stay positive, lovebugs <3"

• Rin...
• Taken for 1 to 2 years
• August 20, 2020

"I take Viibryd for morning sadness. One side effect of that is insomnia. But it works so well. So I take mirtazapine to help me sleep. It works great. And yes, some of the visuals occurred while adapting. However, I have an issue where one manufacturer's pills allow me to wake refreshed. Another manufacturer's has me waking feeling all creepy. Kaiser just sends me what they have in stock. I know there shouldn't be a difference. But there is."

• bli...
• Taken for 1 to 6 months
• October 15, 2015

"Best antidepressant I have taken. After trying different drugs for my severe depression, including citalopram, which gave me constant diarrhea, then sertraline, which gave me diarrhea as well, I was switched to mirtazapine. This has lifted my mood greatly, and I sleep better at night too."

• Bub...
• Taken for 1 to 6 months
• April 26, 2016

"I'm about 4 weeks in on 15 mg, slowly transitioning to 30 mg. I'm a 6'2 male in my mid-30s, and before I began mirtazapine, I was 182 pounds. Today, I'm 199 pounds in just 4 weeks! One other condition this drug is used for is an appetite stimulant, and I can see why, as I will eat anything anyone puts in front of me. I feel like an ogre now when I eat, literally, I can eat 2 full meals at a time. Trying to exercise more to fight off the crazy gains. Overall, I'm taking this for major depression, anxiety, and insomnia. So far, so good for those three, things are slowly getting better. The dreams from mirtazapine are crazy! Every night is a new adventure. I don't feel too groggy the next day. I will post an update in a few weeks once the 30 mg has a chance to kick in."

• Anonymous
• Taken for less than 1 month
• December 24, 2021

Mirtazapine "Wow. I have always refused to take medication after a bad experience years ago with citalopram. This time around, I spiraled after a bad breakup and had brief psychotic disorder. I hardly left my bed. Couldn't eat. Couldn't sleep. My doctor prescribed me this medication, and it has worked wonders. Slept a full night, and three days in, I was eating again. I'm on day nine now, and I am already experiencing positives to my mood. I have hardly had any side effects, which is also a bonus! Everyone is different, but for me, this medication saved my life."

• Kel...
• Taken for less than 1 month
• November 12, 2019

"So I’ve only been on this medication for a little over a week. I’m currently taking Prozac in the morning and mirtazapine at night. I was recently put on mirtazapine because my depression tends to stop my appetite, and I’ve lost a ton of weight. My doctor added mirtazapine to my regimen to help me gain weight and also help with my OCD and anxiety. When I tell you I want to eat things I don’t even like... I have cravings for seafood, and I’ve never liked seafood. I’ve also felt a lot more relaxed, and it helps me sleep so well. So far, I feel like my spirits are up, and I’m on the road to gaining weight, which is a must for me."

• Wil...
• Taken for 6 months to 1 year
• November 3, 2023

"Second time around on mirtazapine after taking myself off it. Have to say, it works well for me. After trying sertraline (godawful and never again), I was put on mirtazapine after being told it's likely I don't get along with SSRIs. Quality of sleep has improved, depression is 100x easier to deal with. PTSD symptoms have eased (though not disappeared - and they won't by just taking medication). But overall I'm very happy starting this drug again. I will say the increased appetite and cravings for sugar can get overwhelming at times, so please try and be kind to yourself and regulate food within reason. As someone with an ED, it's difficult at times to cope with. If you struggle with sertraline or citalopram, try mirtazapine, my GP told me it works completely differently from the above, and if, like me, you don't get along with the above, mirtazapine will hopefully be the best alternative. Everything works differently for everyone, however, so take this with a pinch of salt!"

• Glo...
• Taken for less than 1 month
• May 4, 2023

Mirtazapine "I am battling severe insomnia, and I took this because it helps with sleep, according to some people, but for me, it did not work at all. Insomnia persists, and I feel like a zombie. Not a good medicine for me."

• MDD...
• Taken for 10 years or more
• October 27, 2019

"I have been taking mirtazapine for 11 years for MDD, now at 45 mgs. As a person who cannot tolerate SSRI or SNRI antidepressant medications, this has been what keeps me functional. While it doesn't anymore, it also worked beautifully to treat my sleep disorder and extreme insomnia for the first few years. The only side effect that I personally deal with is nighttime binge eating and the resulting weight gain. Whatever. I'd rather be slightly overweight and able to function and be part of life."

• Emi...
• Taken for less than 1 month
• July 13, 2023

Mirtazapine "After an injury that left me with chronic sciatica, I was so depressed and anxious that I had episodes of crying uncontrollably and panic attacks that lasted hours. I kept having insomnia, and I had no appetite even when I was hungry. I was having intense bouts of suicidal ideation multiple times per week. Between being on this drug at 7.5 mg every night for just over a week and starting an intensive outpatient program, I'm sleeping 8 hours every night, down to only minimal suicidal thoughts. While I'm still grieving for my old life, I'm no longer crying uncontrollably for hours at a time or overwhelmed by tiny things. It's like the difference between 3-foot waves and 6-foot waves. Without my pain level changing, this has made my life feel doable. And I actually feel like eating again. The only side effect has been minor morning sleepiness. I do advise making sure you have healthy food around when starting this drug if you tend to gain weight."