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Methenamine User Reviews & Ratings (Page 2)

Brand names: Hiprex

Methenamine has an average rating of 8.2 out of 10 from a total of 105 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Methenamine

Commonly mentioned side effects
  • Reg...
  • Taken for less than 1 month
  • July 11, 2017

For Bladder Infection "Seems to be working for me, but time will tell if it helps to prevent recurring infections, as, like many, I am very susceptible to UTIs. I have no antibiotic resistance that I know of, but I would rather not take them if I can avoid it! Re: concerns about the formation of formaldehyde in the gut, that sounded scary to me too, but after a bit of reading, I learned that formaldehyde does not accumulate in the body. The body metabolizes it to formic acid, which acidifies the urine and kills the bugs (it is an antibacterial and often used as a preservative in food). That said, formaldehyde is a known carcinogen, so I will be monitoring my use."

8 / 10
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57 Report
  • Kba...
  • Taken for 1 to 2 years
  • April 2, 2013

For Bladder Infection "I first had a urinary tract infection at the age of 16 and suffered with them frequently since that time until around 1 year and a half ago (at age 26) when I was introduced to Hiprex by a friend. I used Hiprex at that time and since then haven't needed to use it again until recently. I'm not too happy about having a UTI right now, but the fact I haven't had one for a year and a half has been so good. I'm just hoping that by taking Hiprex again this time round, it will shorten the duration of the UTI and alleviate the symptoms quickly. I'm hoping to avoid antibiotics, if possible."

7 / 10
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80 Report
  • Che...
  • July 31, 2017

For Kidney Infections "I have had constant kidney/UTI infections. The doctor has tried everything. He put me on a low-dose antibiotic over a period of time, this worked for a while. Constantly, I would be on a double dose of antibiotics, and after taking the course as directed and having intercourse again, the infection would come back. I've bathed and done all the right things, but the infection would always come back. I have gone through early menopause, and kidney/UTI infections are part of the course as your body starts having fewer hormones, something we are not told. I went on a quest to find another alternative and tried Hiprex and haven't looked back. I am very happy with the product Hiprex."

10 / 10
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55 Report
  • Lou...
  • Taken for less than 1 month
  • November 9, 2021

For Bladder Infection "I started this drug around 3 weeks ago. It worked within hours. My quality of life was terrible with frequent UTIs and daily chills/fevers. Over the last 12 years, I tried every drug from doctors and hospitals in the book, also bought vitamins and herbs, etc., anything I read about that promised to help. A consultant gave it to me as a last resort before my bladder was to be removed. Early days, but so far, so good!"

10 / 10
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27 Report
  • Rik...
  • Taken for 5 to 10 years
  • March 15, 2021

For Prevention of Bladder infection "I have a long-term urethral catheter. I used to get frequent UTIs. I seem to be permanently on antibiotics. My neurologist suggested using Hiprex. I started using it about nine years ago, and since then, I have only had two infections. I have found no side effects, and I just need an annual renal function blood test."

10 / 10
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31 Report

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  • Deb...
  • Taken for 6 months to 1 year
  • August 13, 2020

For Prevention of Bladder infection "Retention of urine was creating a reservoir for bacteria to flourish and was the cause of the repeated UTIs over several years. I had a urethra dilation, which has led to better flow and more complete bladder emptying. I also take Hiprex once a day and have not had an infection for nearly a year. Bliss. The tablet itself tastes awful, but a small price to pay."

10 / 10
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32 Report
  • Ros...
  • Taken for less than 1 month
  • January 9, 2020

For Urinary Tract Infection "It is working for me after coming off antibiotics I took for 2 years, but I feel strange, slight moodiness, but at least the pain has gone for now. I’ve been taking it for over a week, just half a tablet twice daily. I’m more tired than usual and feel slightly apathetic, but apart from that, ok."

8 / 10
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38 Report
  • Anonymous
  • Taken for less than 1 month
  • May 4, 2012

For Bladder Infection "I have suffered since I was 12 years old from bladder infections. I am now 45 years old. I was so hoping this would be my miracle, but unfortunately it is not. I really hoped it would work, but I am back to dealing with bladder infections. It just makes life so difficult. I also suffer from irritable bowel syndrome."

3 / 10
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76 Report
  • Tla...
  • Taken for less than 1 month
  • August 15, 2020

For Bladder Infection "Bought Hiprex over the counter (here in Australia) 2 years ago and only needed to be on it for 4-5 days. Twice since, as soon as there was even a hint of well-recognized symptoms, I took a dose twice with a lot of water and was cured the next morning. Some people will likely need bigger doses, I'm lucky I'm okay with less. By the way, I suffered from frequent UTIs over 10 years ago until my GP organized an IVP (special CT scan of kidneys) and discovered a small kidney stone, the seat of the infections. After sound wave removal (lithotripsy), the UTIs virtually disappeared. Only get the occasional one now."

10 / 10
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32 Report
  • Dig...
  • Taken for 1 to 2 years
  • March 14, 2021

For Bladder Infection "I have a double collection sack on my right kidney. Had nothing but problems with it over the years. After my hysterectomy in 2019, I suffered damage to my bladder, then followed horrendous UTIs and had 16 lots of antibiotics. I was then put on Hiprex, and I haven't had one UTI. Amazing stuff."

10 / 10
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26 Report
  • Any...
  • Taken for 1 to 2 years
  • May 22, 2019

For Kidney Infections "After having several hours of acute pyelonephritis, admissions to the hospital, and most of the antibiotics relevant to my problem following surgery, I was prescribed Hiprex (Methenamine hippurate). It has been a resounding success for all my kidney urinary issues. Unfortunately, I am now having dreadful problems getting this product. I live in the UK. Is anyone else having difficulty?"

9 / 10
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34 Report
  • Ann...
  • Taken for 6 months to 1 year
  • August 10, 2019

For Prevention of Bladder infection "I am in London, and my GP prescribes Hiprex to prevent constant UTIs. The drug has been successful, but there has been no supply in my area, so I have bought it in Australia at a reputable pharmacy that ships overseas. Hiprex is bought over the counter in Australia, which is useful. I paid for it via PayPal, which takes your money about the same time as the delivery. In my case, after delivery. I bought two bottles of 1g Hiprex. The total cost was £63.21, which included airmail. I paid VAT on the purchase when it arrived in the UK. Found them efficient to deal with. I rang the distributor in the UK, and they said supplies were being sent out on August 12th. Someone told me they are going to switch manufacturing to the UK. I hope so. I hope my experience helps others."

9 / 10
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33 Report
  • neu...
  • November 27, 2008

For Prevention of Bladder infection "Thousands of patients with neurogenic dysfunction of the lower urinary tract were treated by me with Mandelamine 1g three times daily for the past 20 years, with very good results and without any side effects. It decreased urinary infections in this group of patients by about 60 - 70%."

9 / 10
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69 Report
  • Swe...
  • Taken for 1 to 6 months
  • July 15, 2024

For Bladder Infection "I have had a Suprapubic Catheter for 10 years with many bladder infections. I found that within a week of finishing a course of antibiotics, the UTI returned. I was recently put on a medication for another issue that caused more frequent UTIs and as a result, I had to have frequent bladder flushes. My doctor put me on Hiprex a couple of months ago and it has been a miracle for me, no more UTIs. I just take the Hiprex morning and night with a Vit C tablet. I wish I had discovered it sooner, it's made such a difference to my well-being so far and I just hope it stays this way."

10 / 10
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  • Joa...
  • Taken for 1 to 6 months
  • June 24, 2019

For Bladder Infection "I have been on Hiprex for a month and a half along with strong antibiotics, still have a bacterial infection, but it seems to be moving in the right direction. Yes, cannot get in the UK, some problem with MEDA Pharmaceuticals (Germany) not supplying Mylan, the distributor. Got mine online from Australia, where they can also be obtained over the counter. The manufacturer is different, 3M, and distributed by Inova. I did double-check with Inova that they were authentic, which they were. Good luck."

8 / 10
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34 Report
  • Ann...
  • Taken for 1 to 2 years
  • August 24, 2022

For Urinary Tract Infection "Suffered UTIs for over 20 years post-menopause 68. Finally, managed to get Hiprex on prescription from my NHS doctor. Resistant to most antibiotics. Got my life back, so reduced to 1 g at night, stopped the morning tablet for about 10 days. Got my first infection 3 days ago, hoped I could do without as uncomfortable about the formaldehyde action, becoming Hiprex-dependent and long-term side effects. Taken Macrobid 3 days now, feeling rough will take Hiprex again ASAP. Have Macrobid as a standby to take on the first sign of infection and used only needed to take one tablet of 100 mg twice while on Hiprex for the past 18 months. I haven’t come across anyone that has taken Hiprex long term, i.e., 2 yrs plus? Please post if you have heard of people that have been taking it for longer than 2 years."

10 / 10
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17 Report
  • Cla...
  • Taken for 1 to 6 months
  • September 28, 2019

For Bladder Infection "Have been put on Hiprex when couldn’t tolerate antibiotics. Sadly, my frequency symptoms and pain have increased with Hiprex. I have heard that Hiprex is one of those drugs that works or doesn’t work for you, and even with the addition of Vitamin C, no improvement."

2 / 10
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30 Report
  • Jan...
  • August 30, 2017

For Urinary Tract Infection "Two years ago, I got my first ever UTI at 55 years. I had 8 or 9 sets of varying antibiotics, nothing seemed to work. So, my GP placed me on Ciprofloxacin for 7 days and, at the same time, on Hiprex this year and told me to take cranberry as well. The last 2 M/C/S tests have indicated that there are no significant bacteria detected. But I am worried about long-term use and bone health, as acidity adds to bone depletion, as I have been diagnosed with osteopenia."

8 / 10
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39 Report
  • Sab...
  • Taken for 1 to 6 months
  • June 13, 2023

For Urinary Tract Infection "I have suffered from UTIs for years. I have been to so many urologists, I’m literally exhausted. Antibiotic after antibiotic, they would help me for a little while, about two to three weeks, then the infection would return, and always a different strain. This year, 2023, I started on Hiprex twice daily and vitamin C once daily. Well, we are in June, and thank you to my physician assistant who prescribes it for me. All the urologists I went to, at least six, never mentioned this medication to me. It honestly works. Thank goodness I had no major side effects, apart from mild stomach problems and occasional diarrhea. I can deal with stomach discomfort. No UTI, YEAH!"

10 / 10
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12 Report
  • Lis...
  • August 10, 2017

For Kidney Infections "After becoming sexually active, I began suffering recurrent UTIs and bladder infections, of which the only non-intravenous antibiotic I wasn't resistant to was Macrodantin. However, this was only a short-term solution, and after collapsing and having a week-long stint in the hospital from a kidney infection, a specialist prescribed Hiprex. It has been 3 months since, and all UTI-like symptoms have faded away and not returned. The only thing I have to fault is the stomach acid-like taste, and it's rather pricey, but much, much better than being constantly in pain and discomfort. So far, so good!"

9 / 10
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35 Report
  • Pri...
  • Taken for less than 1 month
  • November 5, 2019

For Urinary Tract Infection "Hiprex with Vit C 500 mg twice a day for recurrent UTI prevention. I was on Macrodantin 50 mg for 4 months and got a UTI recently. My Dr. at Northwestern Univ. wanted me to try Hiprex. As soon as I took the first pill, I felt the burning through my stomach and bladder. It gave me diarrhea, painful urination, nausea, back pain, vaginal burning, and my bladder started leaking. Tried with Pyridium for 2 days, a little better, but once the Pyridium stops working, this is killing me. I did 6 days, and I'm done. Sucks for me!"

2 / 10
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31 Report
  • Nic...
  • January 27, 2021

For Bladder Infection "I have had a urinary tract infection for 18 months. I had all the usual antibiotics, but they didn’t work. I researched Hiprex, and my GP agreed to let me try it. The only side effect I had was painful urination, which has now stopped. If I stop the Hiprex, the infection returns. I don’t know where this will end. I also take 1 g of Trimethoprim at night, but it is now not available because of Brexit. I live in N. Ireland and have no problems getting the prescription, so I don’t understand why it’s not available. I also take Waterfall D-mannose 2 daily on the advice of my urologist."

8 / 10
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21 Report
  • Ros...
  • March 1, 2017

For Bladder Infection "I have a lot of bacteria going on in my system all the time, and the UTIs are constant and horrendous. Like others have stated, I just can't be on antibiotics all the time, so I have been trying other things. D-mannose powder is wonderful, but it's quite expensive, and when I'm really bad, it doesn't always work. Just discovered the Hiprex tablets over the counter here in Australia at the chemist. I looked it up on the net for information and how it works and didn't feel really comfortable about the substance turning to formaldehyde in the gut."

8 / 10
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41 Report
  • Met...
  • Taken for 5 to 10 years
  • September 28, 2014

For Prevention of Bladder infection "I've used Mandelamine/Methenamine for 7 years, and it works for me. I never get less than a year between infections, but I am now 2 years and 9 months without an infection after previously trying almost every medicine available with mixed results. Sometimes I'd get a breakthrough infection after 2 months, and other medicines would last 5 weeks, being taken every day. I've had no bad effects, taking 1 MG at bedtime, but I do drink the glass of water with it. I get overnight discomfort if I don't."

10 / 10
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42 Report
  • Gab...
  • Taken for 1 to 6 months
  • April 9, 2024

For Bladder Infection "This all started back in June 2023. I got a UTI that would not go away, finally, it did after 5 days of Bactrim. Then I got another infection in September, and this is when I realized this is more serious and dangerous. I got another infection in February 2024 and decided to start Hiprex right after I finished antibiotics. A lot of my urine labs would come back negative, and doctors did not want to prescribe antibiotics, so I had to get antibiotics overseas. I took the antibiotic which calmed my symptoms and started Hiprex. It has been 2 months on Hiprex, and I have been doing great! It is still too early to tell, but I am thankful just to have 2 months where I had my life back. Hopefully, it keeps working long-term. Will come back with updates!"

10 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.