Skip to main content

Methenamine and Depression: What Users Say

Brand names: Hiprex

Depression: mentioned by 3 users (2.9%)

Based on user experiences from 105 Methenamine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bad taste 5.7%
burning 3.8%
difficulty urinating 3.8%
bladder issues 2.9%
depression 2.9%
diarrhea 2.9%
headaches 2.9%

Reviews for Methenamine

Commonly mentioned side effects
  • Lif...
  • Taken for less than 1 month
  • September 15, 2019

For Urinary Tract Infection "I was prescribed Hiprex a week ago to help control painful recurring UTIs. About 3 days after taking it, I started to feel and look exhausted, and I’ve had trouble getting and staying asleep at night. I look in the mirror, and my eyes are lifeless, and I have circles under my eyes. Even my family has commented on how bad I look (Mom said the spark is gone from my eyes). I’ve also had urine dribbling into my underwear out of nowhere (I’m wearing a pad for the first time in my life), sharp pains in my urethra, and increased urination. I’ve also felt extremely depressed and have been emotionless since this med (very strange, feelingless mood). There is absolutely a correlation between Hiprex and how I feel and look. I believe this is a dangerous drug. I’m going to call my doctor on Monday to see if I should stop, and he’ll probably say yes out of abundance of caution, and then I’ll be back to recurring UTIs. Can’t win for losing."

2 / 10
Was this helpful?YesNo
50 Report
  • Lif...
  • Taken for less than 1 month
  • September 15, 2019

For Urinary Tract Infection "I was prescribed Hiprex a week ago to help control painful recurring UTIs. About 3 days after taking it, I started to feel and look exhausted, and I’ve had trouble getting and staying asleep at night. I look in the mirror, and my eyes are lifeless, and I have circles under my eyes. Even my family has commented on how bad I look (Mom said the spark is gone from my eyes). I’ve also had urine dribbling into my underwear out of nowhere (I’m wearing a pad for the first time in my life), sharp pains in my urethra, and increased urination. I’ve also felt extremely depressed and have been emotionless since this med (very strange, feelingless mood). There is absolutely a correlation between Hiprex and how I feel and look. I believe this is a dangerous drug. I’m going to call my doctor on Monday to see if I should stop, and he’ll probably say yes out of abundance of caution, and then I’ll be back to recurring UTIs. Can’t win for losing."

2 / 10
Was this helpful?YesNo
50 Report
  • Ros...
  • Taken for less than 1 month
  • January 9, 2020

For Urinary Tract Infection "It is working for me after coming off antibiotics I took for 2 years, but I feel strange, slight moodiness, but at least the pain has gone for now. I’ve been taking it for over a week, just half a tablet twice daily. I’m more tired than usual and feel slightly apathetic, but apart from that, ok."

8 / 10
Was this helpful?YesNo
38 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.