Lurasidone and Depression: What Users Say (Page 2)

• Pol...
• Taken for 1 to 6 months
• April 12, 2016

Lurasidone for Bipolar Disorder "Worst medicine for bipolar I have tried, it made me extremely angry and irritable. I got extreme hot flashes that got worse during the night, which prevented me from sleeping. It also made me feel more depressed and I actually gained weight on it. The withdrawals weren't that bad but the hot flashes haven't gone away completely. Not a good drug for me personally but I hope it works well for others."

• Juj...
• Taken for 1 to 6 months
• November 18, 2019

Lurasidone for Bipolar Disorder "I never heard of Restless Legs Syndrome till being on Latuda for 6 months. I have bipolar and after taking 40 mg for two months, increasing to 80 mg and then dropping to 40 mg after 5 episodes of restless legs, developed worse depression and insomnia I have ever experienced, had to stop taking Latuda after the 6th episode of worse Restless Legs Syndrome. After 4 hours of another Restless Legs Syndrome torture, crying on the floor, my husband drove me to the hospital."

• You...
• Taken for 1 to 6 months
• December 17, 2020

Lurasidone for Bipolar Disorder "Not liking this medicine so far. It’s the only one that has literally made my bipolar episodes and depression like 10,000 times worse. And the longer I stay on it, the worse it is. Which is weird because when I first started it at a low dose, it worked wonderfully, but then it randomly stopped working, and now it’s just completely working against me. This medicine confuses me, and not in a good way."

• A1a...
• Taken for less than 1 month
• November 6, 2019

Lurasidone for Bipolar Disorder "I have only just started Latuda for Bipolar I, it's been 4 days. I was previously on Abilify for 1 month, and the side effects were horrible for me. I was restless, had blurred vision, was depressed, headaches, etc., from day 1. My psychiatrist switched me from the Abilify to Latuda 40 mg, and I feel really good so far. I have no side effects at all except mild sleepiness, and I feel very consistent within myself. I would give it 10/10, but as I said, it's only been 4 days, so I don't want to get my hopes up. But so far, so good! I still feel a little down sometimes, but have none of the side effects I did with Abilify, so I'm hoping with time I will have even more improvement. I'm so thankful, as I couldn't survive another day on Abilify. Latuda seems to be what works for me. I hope you all find what works for you!"

• Kae...
• Taken for less than 1 month
• September 15, 2018

Lurasidone for Bipolar Disorder "It makes me go off on these rage-filled tangents and tantrums - that scare my family and me. But whenever I tell them the Latuda makes me feel this way, they ignore what I say, and so does the pdoc. I am so depressed, I have gained 20 lbs+ from taking it. I don't like this med, but nobody listens to me."

• I...
• June 19, 2016

Lurasidone for Schizophrenia "I have been taking this medication for 2 years now. The first year, it worked like a wonder pill. Minimal side effects such as nausea and drowsiness after ingesting it. Sometimes I would have a feeling of impending doom, like if my life was going to end after I took the pill. Later, this medicine turned out horrible. I don't know what a night's sleep is. It causes me severe insomnia. I feel always tired, even after sleeping 15 hours. I'm suffering from severe depression from this medicine. It makes me irritable and angry. It drains me of motivation. The only thing I can say good about this medicine is that it has caused me no weight gain whatsoever. This medication drains me from being able to live life."

• Mik...
• Taken for 1 to 6 months
• November 18, 2018

Lurasidone for Bipolar Disorder "The first 2 weeks or so on 60 mg, I had terrible akathisia, I'd be on all fours pounding the ground trying not to scream because it was so bad. It got upped to 80 mg, and I started taking it as the last thing before going to bed, which helped. I'm almost 2 months in and am tapering off because it's caused anxiety, it's messed up my gait, and I don't walk normally now. It makes me talk slow and slurred, I get random muscle jerks in my legs somewhat frequently, and it makes me feel absolutely apathetic about everything. I feel like my emotions are completely flat, I'm not sad but also not happy, just flat."

• Anonymous
• Taken for 1 to 6 months
• March 3, 2023

Lurasidone for Schizophrenia "Latuda sucks. I was only on 20 mg once a day for 4 weeks and on 40 mg once a day for 2 weeks. This med made suicidal ideations worse, and I ended up self-harming. I had facial muscle spasms, paranoia, and anxiety, and the depression worsened. I had to take leave off work because of all of this. Before, I was on risperidone, and I was tired at work, so I asked for a new medicine so I could work more hours at work without being tired and falling asleep standing up. I'd take that overall, this nonsense Latuda gave me. Now, I haven't worked for 2 months. I'm behind on bills. I am on permanent disability, but that's not something anyone can live off of. It's why I need this job and why I need medicine that will help me so I can work more than 4 hours a day."

• Lee...
• September 24, 2015

Lurasidone for Bipolar Disorder "Recently diagnosed bipolar. I was on Latuda 40 mg and felt good. After two weeks of the 80 mg that my psychiatrist prescribed me, I started to notice severe depression. It would occur about 30 minutes after taking. I was even having suicidal thoughts, which has never happened to me. The first night I stopped taking it, I did not feel depressed at all. The med just didn't work for me. We are going to try Abilify next."

• Lau...
• Taken for 6 months to 1 year
• January 12, 2016

Lurasidone for Bipolar Disorder "I started Latuda 11 months ago (20 mg, then 40, now 60), and I think all it does is trigger hypomanic episodes with dose increases, and when those end, I end up feeling more depressed than ever. The depressive episodes on Latuda have been some of my worst in over three years, and the hypomanic episodes seem to last longer than usual. I also get ridiculously restless, having trouble falling asleep, but then having trouble waking up (I sleep through alarms for over an hour). I thought I found the drug for me, but I'll be seeing my psychiatrist soon to switch. At least it worked well for a while?"

• Mik...
• Taken for 6 months to 1 year
• April 5, 2016

Lurasidone for Bipolar Disorder "Suffering from Bipolar I, I was prescribed Latuda. Over a 1-year period of taking the drug, I lost motivation, became depressed, and bordered on suicidal. With a lifetime of struggling with mania and anxiety, I've never been suicidal until taking this drug. It's also a tier 3, so it will run your most expensive copay or thousands a month without copays."

• Mik...
• Taken for 6 months to 1 year
• April 5, 2016

Lurasidone for Bipolar Disorder "Suffering from Bipolar I, I was prescribed Latuda. Over a 1-year period of taking the drug, I lost motivation, became depressed, and bordered on suicidal. With a lifetime of struggling with mania and anxiety, I've never been suicidal until taking this drug. It's also a tier 3, so it will run your most expensive copay or thousands a month without copays."

• GBl...
• Taken for 6 months to 1 year
• March 21, 2016

Lurasidone for Bipolar Disorder "I am bipolar II and have been taking Lamictal 200 mg for the past year with great success, but I started experiencing severe depression after a manic episode. My psych prescribed Latuda about 9 months ago. In the beginning, I was on 40 mg and I began to feel better, but my psych thought if 40 mg was good, 60 mg was better. Well, that turned me into a zombie. My whole body slowed down. I became extremely claustrophobic, like I was going to stop breathing. I had to take it at night with dinner because it knocked me right out. I had my psych reduce my dosage to 40 mg, then to 20 mg. However, now that I'm on 20 mg, I still feel some depression, so I don't know if it's worth being on. I do get Latuda for $15 a month using their savings card with my insurance."

• Anonymous
• Taken for less than 1 month
• June 24, 2020

Lurasidone "20 mg Latuda for 1 week, 40 mg for 1 week for major depression. Came from Geodon and went right back to Geodon. Latuda gave me active/vivid borderline nightmares every single night. It made me more depressed than I have been in years. Traumatic memories that I haven't thought about in years came back out of nowhere without trigger! These episodes would happen 5-8 times randomly throughout the day constantly. I was crying and begging to be able to get off it. Two weeks was too long on this drug. Be careful, you all!"

• Laz...
• Taken for 1 to 6 months
• April 28, 2021

Lurasidone for Bipolar Disorder "After many different medications, my APRN started me on Latuda 40 mg. At first, I started having depressive episodes with periods of uncontrollable crying. We increased the dosage to 80 mg a month ago. I am now calling out of work because of an uncontrolled fear of work. I have lost interest in everything and cry uncontrollably. I find myself contemplating suicide, only to break down and cry thinking about my kids. This medication is horrible! I hope I can correct this soon, the feelings are paralyzing me."

• Laz...
• Taken for 1 to 6 months
• April 28, 2021

Lurasidone for Bipolar Disorder "After many different medications, my APRN started me on Latuda 40 mg. At first, I started having depressive episodes with periods of uncontrollable crying. We increased the dosage to 80 mg a month ago. I am now calling out of work because of an uncontrolled fear of work. I have lost interest in everything and cry uncontrollably. I find myself contemplating suicide, only to break down and cry thinking about my kids. This medication is horrible! I hope I can correct this soon, the feelings are paralyzing me."

• Lis...
• April 15, 2013

Lurasidone for Bipolar Disorder "Been on Latuda 40 mg for about three weeks. I'm still having some depression, sadness, but not nearly what I was when I first started on it. My psych doc and I are considering a jump to 80 mg, but I'll be trying to get pregnant soon. Other than that, I think it's doing okay."

• Lis...
• April 15, 2013

Lurasidone for Bipolar Disorder "Been on Latuda 40 mg for about three weeks. I'm still having some depression, sadness, but not nearly what I was when I first started on it. My psych doc and I are considering a jump to 80 mg, but I'll be trying to get pregnant soon. Other than that, I think it's doing okay."

• jen...
• Taken for 6 months to 1 year
• April 5, 2013

Lurasidone for Bipolar Disorder "Latuda took away the voices, but caused me to have bad thoughts and depression, especially at night. It, however, allowed me to lose 20 lbs. I discontinued it and started on Geodon last week, my mood has dramatically improved, and I feel great. Hopefully, it doesn't cause weight gain."

• Bip...
• Taken for 6 months to 1 year
• January 20, 2017

Lurasidone for Bipolar Disorder "I had been on Seroquel since 1997 and had gained a lot of weight. I also had the side effects of type 2 diabetes, high cholesterol, etc., from taking it so long. But Seroquel worked for me. So in an effort to lose weight and the 'bad' side effects, I switched to Latuda. Latuda didn't do squat for me in the sleep department, so I ended up taking a half pill of Seroquel and a dose of Latuda. This worked well for about a year. I lost a ton of weight and my overall health improved. However, I slipped into a major depressive episode in less than a year and had to go back to the 'tried and true' Seroquel. Feeling better, but gained back a lot of weight. Never thought a drug marketed for BP depression would make me depressed."

• bar...
• Taken for 1 to 2 years
• October 9, 2022

For Schizoaffective Disorder "I have been on Lurasidone for the past twenty months and find it wonderful. It is used in conjunction with my main antipsychotic, which is Paliperidone monthly injection. I chose Lurasidone because of it being weight neutral. With any other antipsychotic, I gained huge weight. For seventeen years, I've battled with other antipsychotic medication and couldn't find the right combination for me. While in the hospital, my doctor recommended Lurasidone to help reduce my weight, and it worked brilliantly. I lost all my excess weight, and my intention was to be solely on Lurasidone, but as my dosage increased from 40 mg to 80 mg, I found myself getting more and more depressed. This caused me to keep the Paliperidone injection and use Lurasidone of 40 mg nightly along with an antidepressant. I'm now very stable with this combination. No more voices in my head, no more hospital admissions. I'm very alert during the daytime and get proper sleep at night. Finally, I'm me again, and I'm healthy and fit."

• ran...
• Taken for less than 1 month
• September 28, 2017

Lurasidone for Schizophrenia "This is the worst drug I ever took prescribed for schizotypal personality disorder and major depression by one of my past psychiatrists. I don't even understand how this helps other people at all. The psychiatrist thought it might help me, according to her, it was because I mentioned 'anger,' which was very black and white of her. Um, hello...I have severe depression, yet she goes ahead and prescribes me an antipsychotic that shouldn't have been prescribed to someone with depression like me. So, I go on a very low dose, after three days of walking like a zombie, barely able to keep my eyes open, agitated, worse depression, I developed convulsions when trying to sleep on the third night, screaming, crying in pain, barely able to breathe and was rushed to the hospital, given Ativan to calm me down, stopped Latuda entirely."

• Caf...
• Taken for 1 to 6 months
• September 11, 2017

Lurasidone for Schizophrenia "I have been on it about a month. I've lost all motivation to do anything other than sleep. I'm nervous all the time. I can't feel my left hand. I have nightmares every night. I've lost all desire to eat. My vision is blurry. My psychiatrist is of no use as he only works three hours a week since he's borrowed from another program, and I have no way to get in touch with him. This is why I don't trust doctors."

• Car...
• Taken for less than 1 month
• October 31, 2019

Lurasidone for Bipolar Disorder "I’ve literally only been on Latuda for 3 days, and ever since I started taking it, my vision is messed up, I feel sick to my stomach, and emotionally I feel kind of numb. Not sure if these will go away, but I start a new job soon, so hopefully it gets better. Fingers crossed."

• Mel...
• November 15, 2017

Lurasidone for Bipolar Disorder "This drug was a terrible experience for me. It worsened my depression and anxiety symptoms, but one of the most unbearable parts was the restless leg syndrome. I couldn't sleep. I would lay awake for hours with the craziest feeling in my legs. Brain fog. I slowly was weaning off and then quit cold turkey because I wanted this OUT of my system! All in all, do NOT recommend."