Lisinopril and Swelling: What Users Say (Page 2)

• Anonymous
• November 2, 2009

For High Blood Pressure "Been on medication for HBP for 7 months (also taking Bystolic). Had a reaction of angioedema where my face swelled, and then a few days later got hives on my arms and legs. ER doctor explained it's technically NOT an allergic reaction (i.e., not histamine related), so Benadryl will not help with the swelling. Given prednisone and also taking Tylenol. He told me the drug can be taken for decades without any adverse reaction, and then one day, you suddenly get swelling. Having a reaction rules out using any of the ACE inhibitor drugs. Too bad - it was working really well for me. On Cardizem now."

• Noe...
• January 26, 2018

For High Blood Pressure "First time taking this medicine, had an allergic reaction, only took one, and apparently one is all it took. Right side of lip started to swell, took it at 10 pm the previous night, next day, swelling continued to increase. Checked blood pressure often, numbers were lower than what I’ve ever seen. A normal range for me was around 150/99-110, 115/80 afterwards. Although numbers were good, I will not take ever again. Going to try Norvasc."

• OhD...
• Taken for less than 1 month
• September 23, 2017

For Migraine Prevention "I am a long-time sufferer of severe migraines, which interfere with my life. I take propranolol as preventative and Relpax for breakthrough 4-6 times a month. My PCP prescribed a small dose of lisinopril in addition to help. No idea if the drug would have helped migraines. First week, I had small outbreaks of hives I did not connect with lisinopril. Then I had an outbreak that within a day covered my entire body (there were plate-sized hives that overlapped, with smaller outbreaks on top). My mouth and throat began swelling, and I got to the ER ASAP. Very close to anaphylaxis. Learned that this is a known side effect of lisinopril. Package warning is not clear enough."

• Bet...
• Taken for 10 years or more
• May 16, 2018

For High Blood Pressure "Someone I know on this medication had taken it for ten years, ended up in the ER. His face and throat swelled, they were unable to intubate him, so he had a tracheotomy. After being sedated in the ICU for several days, pneumonia set in. Day 6 in the ICU, they gradually awoke him, his stomach was tight and swollen. After an X-ray or CT scan, he was rushed to emergency surgery, he had a bowel blockage, which resulted in perforation. It was leaking into his stomach, they made an incision all the way down his stomach and removed part of his intestine. So he’s been sedated again for 3 more days, they have been waking him a portion of the day. Now he’s spiked a fever of 102. Tomorrow will be 2 weeks in the ICU, and he’s still not off the vent or even been awake for a significant time."

• 271...
• November 19, 2017

For High Blood Pressure "I’ve been taking this drug for about a week (half a pill once a day). I experienced a dizzy feeling, then last night after a nap, I went to the restroom, and to my dismay, when I checked my face in the mirror, the left bottom part of my lip was very swollen. It scared me so much that when I checked my blood pressure, it was 186/114. I calmed down, took a hot shower, and checked my pressure, and it was back to normal. Today, my lip is almost back to normal. I’ll never take this again. Like other reviews I’ve read, I will continue to eat right and exercise. I’m not overweight at all, and I will overcome the condition. Maybe the drug helped to bring the pressure under control, but now I’ll keep it there."

• Med...
• November 23, 2017

For High Blood Pressure "Have been taking lisinopril with hydrochlorothiazide for about a year. Have been experiencing dry cough and dizziness. Also, it has not controlled blood pressure. Recently, have been coughing harder and longer. At my last visit, my doctor changed my medicine, stating that it can cause angioedema. My siblings have had the same experience. Bad drug. Do research before taking any medication."

• Ama...
• January 9, 2011

For High Blood Pressure "I am 27 years old and have been taking lisinopril for almost 2 years for high blood pressure, which also caused very frequent headaches. I was first prescribed 10 mg per day. I had a lot of lightheadedness, and I actually fainted once. My cardiologist then lowered my dosage to 5 mg per day. My headaches are virtually gone. I haven't had a true migraine since I started on the drug. I have woken twice with a swollen eye, which I didn't connect to lisinopril until I read the comments here, but other than that, I've had zero side effects since switching to the 5 mg."

• tnf...
• April 14, 2021

For High Blood Pressure "I was switched to lisinopril from atenolol because it appeared atenolol (taken for years but recent dosage increase) caused a rash on my neck. Started lisinopril 10 mg on a Tuesday, by Friday, the skin around my neck and ears was thickened, blistered, and oozing. Went to the doctor the following Monday - rash still attributed to atenolol. BP still high, the doctor said go up to 20 mg of lisinopril. Took another 10 mg within 2 hours, neck swelling, face, and mouth began to itch. I knew angioedema was a side effect of lisinopril because it happened to my 26-year-old son when he took it for his blood pressure. Went to the ER, was told it was a reaction to the drug. Knee started to hurt at the same time. Within 24-48 hours of stopping lisinopril, rash, swelling, and skin thickening began to go away. Within 3 days, skin still red, but all blistering, flaking, and raised areas were gone. Knee pain has not gotten better and is actually worse when I try to stretch or exercise. Horrible experience."

• tnf...
• April 14, 2021

For High Blood Pressure "I was switched to lisinopril from atenolol because it appeared atenolol (taken for years but recent dosage increase) caused a rash on my neck. Started lisinopril 10 mg on a Tuesday, by Friday, the skin around my neck and ears was thickened, blistered, and oozing. Went to the doctor the following Monday - rash still attributed to atenolol. BP still high, the doctor said go up to 20 mg of lisinopril. Took another 10 mg within 2 hours, neck swelling, face, and mouth began to itch. I knew angioedema was a side effect of lisinopril because it happened to my 26-year-old son when he took it for his blood pressure. Went to the ER, was told it was a reaction to the drug. Knee started to hurt at the same time. Within 24-48 hours of stopping lisinopril, rash, swelling, and skin thickening began to go away. Within 3 days, skin still red, but all blistering, flaking, and raised areas were gone. Knee pain has not gotten better and is actually worse when I try to stretch or exercise. Horrible experience."

• Anonymous
• May 24, 2023

"My mother has been having health issues that all seem to have started since she took the drug Lisinopril. About 2 weeks later after starting the drug, she developed really bad swelling of the face and neck and was rushed to the local ER on Friday, 4/28/2023. She was diagnosed with drug-induced angioedema and noted on a CT scan to have almost complete blockage of the airway. She was immediately told to STOP this drug and was admitted to ICU for 2 days and then remained hospitalized for a week for IV Benadryl and IV steroids to get the swelling down. She was then released from the hospital on 5/4/2023. Throughout her time home, my mother has had to take Benadryl daily and Pepcid for continued side effects of the Lisinopril even since stopping it on 4/28/2023."

• Anonymous
• May 24, 2023

"My mother has been having health issues that all seem to have started since she took the drug Lisinopril. About 2 weeks later after starting the drug, she developed really bad swelling of the face and neck and was rushed to the local ER on Friday, 4/28/2023. She was diagnosed with drug-induced angioedema and noted on a CT scan to have almost complete blockage of the airway. She was immediately told to STOP this drug and was admitted to ICU for 2 days and then remained hospitalized for a week for IV Benadryl and IV steroids to get the swelling down. She was then released from the hospital on 5/4/2023. Throughout her time home, my mother has had to take Benadryl daily and Pepcid for continued side effects of the Lisinopril even since stopping it on 4/28/2023."

• Anonymous
• March 5, 2009

For High Blood Pressure "Becomes ineffective after some time. One of the side effects is extreme swelling, which is very unfortunate."

• Poe...
• Taken for less than 1 month
• September 6, 2016

For High Blood Pressure "Sore throat, severe allergy symptoms, loss of appetite, body aches, chest pain, facial swelling, blurred vision, dry cough, headache, weakness."

• Anonymous
• October 14, 2009

For High Blood Pressure "After months of dry cough, finally ended up with a severe allergic reaction, including urticaria (hives) over most of my body for four months, and got angioedema - tongue and face swelled up."

• Anonymous
• August 24, 2009

For High Blood Pressure "I have acquired swelling, edema in both ankles."

• Anonymous
• August 24, 2009

For High Blood Pressure "I have acquired swelling, edema in both ankles."

• Gre...
• Taken for less than 1 month
• September 16, 2016

For High Blood Pressure "Horrible side effects. Angioedema and cough, itchy skin. Dangerous medicine."