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Synthroid User Reviews & Ratings (Page 2)

Synthroid has an average rating of 6.1 out of 10 from a total of 192 reviews on Drugs.com. 51% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Synthroid

  • bbyne...
  • Taken for less than 1 month
  • November 14, 2016

For Underactive Thyroid "I was just diagnosed with hypothyroidism on the last days of October of this year.. My doctor prescribed me 50mcg levothyroxine distributed by Mylan. I was only on the medication for 3 days! The medicine made me so fatigued and tired I could hardly go through my day without wanting to pass out and go to sleep. And not only that but my chest was feeling really uncomfortable. It felt like someone had put 20 pounds on my chest and overall having difficulty taking a deep breathe. My doctor then prescribed me the brand name Synthroid with only 25mcg. I had energy like I havent had in a year, but on the third day i was having shortness of breath, my heart was beating so hard& fast &I felt so lightheaded. Seriously, scariest experience i have had."

3 / 10
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  • DeboraL
  • January 7, 2014

For Hypothyroidism, After Thyroid Removal "I had my thyroid irradiated in 2005 due to Grave's disease caused by Hep C treatment (Ribivirin & Interferon). At first I saw an endocrinologist that prescribed Armour Thyroid but loss of job and insurance forced me to go to a free clinic, where I receive Synthroid. The clinic doesn't seem to understand the difference between experiencing low thyroid levels from naturally occurring hypothyroidism, & complete loss of thyroid. My NP says to me, incredulously, "You take an awful lot of thyroid!", & at that time I was only taking 75mcg a day. Finally after three years of 75 to 100mcg, when I felt absolutely crazy (tired, confused, hair loss, cranky, paranoid, angry, enormous weight gain), she now has me on 150mcg which seems not perfect but better."

9 / 10
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  • sd21
  • Taken for less than 1 month
  • March 4, 2015

For Underactive Thyroid "I began taking my Synthroid three weeks ago and I feel great. First I began breaking my 25 mcg pills into quarters and started out taking only a 1/4 pill. I do this in the morning with a glass of water. I am now taking one 25 mcg pill. My sleeping has improved, I have more energy, my skin looks better and my face does not look tired,. I refused to take this drug initially when I was first diagnosed in 2011 because of a bad scare taking the generic brand, so I let my new meds sit for six months before trying this brand. It works wonders for me and being a life-long gym and karate guy, I have more energy to do laps in the pool and do weights too. I have taken iodine and it works ok, but nothing like my Synthroid. Time will tell."

10 / 10
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Frequently asked questions

  • Pebbles
  • Taken for 5 to 10 years
  • October 25, 2019

For Underactive Thyroid "I do not notice any difference with the medicine, I’m still suffering from depression and I have extreme hair loss and weight gain even if I don’t eat more than 1500 calories a day. High protein, low carbs"

1 / 10
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  • Anonymous
  • February 27, 2008

For Underactive Thyroid "If you boil up balsom tea every day for one month you will cut your colestral and your thyroid down to where you dont have to take drugs. Its no quick fix but its a lot better than taking drugs. My wife is going off a lot of drugs and feels a lot better."

1 / 10
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Are you taking this medicine?

  • Anonymous
  • March 17, 2020

For Hashimoto's disease "Synthroid is terrible it fave me an exacerbation of mental health symptoms! Nervous, restless, anxiety, fatigue, constant dark thoughts and depression. My TSH dropped from .50 to .02 and still no symptoms of hyper just the same symptoms of hypo. Weight gain, tired, depression. I thought I was losing my mind! Trying to adjust psyche meds thinking that was the issue didn't work cuz it was the levo causing the problem. It's difficult to separate symptoms of mental health problems from thyroid problems because they can be similar. Got a referral from PCP to see an Endocrinologist. They switched me to Armour. Significant improvement. Levothyroxine stinks! I'd rather take no thyroid medication and suffer the consequences than take Levothyroxine. "

1 / 10
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  • noname
  • October 11, 2013

For Hypothyroidism, After Thyroid Removal "I have been on synthroid for 20 years. My dosage is 100... To the person whose thyroid was removed and dosage is 250... Sounds a bit high. My tsh level was also 2. 54 the last time I went to the doctor and I feel better than I have in a long time. Anytime I feel a little psycho and mean. I know my levels are off."

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More FAQ

  • Anonymous
  • January 18, 2011

For Hypothyroidism, After Thyroid Removal "I was put on Synthroid after having my thyroid removed due to cancer 6 yrs ago. I think I've been put on every dosage there is. I have not felt the same since. I'm always tired, I wake up wanting to rip someones head off, armpits sweat horribly, cry over nothing, depressed, hair loss, always colder or hotter then people around me, no energy etc. but when I talk to my doctor and explain my issues I'm told that I'm fine. (I beg to differ, needless to say I'm going to see a new doctor next visit). Though I'm sure Synthroid is a wonderful medication, it just doesn't seem to be working for me in my opinion... my doctor seems to think different."

6 / 10
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  • Mills...
  • Taken for 10 years or more
  • August 31, 2017

For Underactive Thyroid "I took synthroid for 10 years, I had severe insomnia so also took sleeping pills everyday, I was depressed to took anti depressants everyday, had high blood pressured so took drugs for that. I couldn't focus at work and just getting up in the morning felt like a chore In 2013, I switched to natural desiccated thyroid drugs (NDT). It felt like waking up from a bad dream. I'm no longer depressed, my sleep hasn't been this good in my entire adult life. It's like night and day, I wish more doctors gave their patients the opportunity to try solutions other then synthroid; because clearly, it doesn't work for everyone."

1 / 10
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  • Jenni...
  • Taken for 5 to 10 years
  • July 3, 2012

For Hypothyroidism, After Thyroid Removal "After being diagnosed with hyperthyroidism, had radioactive iodine treatment in 2004. Was put on Synthroid because the radioactive iodine caused hypothyroidism. When this first happened, I had my levels checked every 3 months, and Synthroid levels were adjusted accordingly to fit my needs. We moved the panels to every 6 months for testing, and then yearly. At this point we are at 150mcgs and I feel great. It has been a journey but Synthroid works better for me than the generic, which we tried for a short time. It depends on what works for you and your body. Don't be afraid to let your endocrinologist know if something isn't working for you, you know yourself best. Good luck."

8 / 10
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  • Thyroid...
  • August 10, 2018

For Hypothyroidism, After Thyroid Removal "It was discover that I had a nodule/goiter on one my thyroids and the other wasn't functioning at all. After all the tests, I was put on Levothyroxine generic. I had all the symptoms named in all the other comments. But to come to find out, I couldn't take the generic. I was switched to synthroid and have been on it for over 30 years. I had to get it adjusted correctly, over the years, finally got it settled. All the symptoms gradually went away and I have been doing great since. This one has done the job for me. The only thing I have to say is that once on this medication, the weight maintenance has been constant with good diet and exercise. I have always separated vitamins and thyroid med, vitamins in the morning and meds at night. It has worked so far and feeling great. I will continue on this medication. To all, do not give up. There is something that will work with your body and it will be like a miracle. This was my miracle."

10 / 10
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  • 50yrO...
  • March 29, 2011

For Hypothyroidism, After Thyroid Removal "My surgeon took charge of my Synthroid medicines - big mistake - it was not until I saw an endocrinologist that I found the correct dosage and felt better. It took 18 months to find the correct dosage. I now take 0.2mg Mon-Fri and add 0.05mg on the weekends. This works for me. I had many problems before I got the right dose, and my surgeon said they were not from the Synthroid - he was wrong. I had extreme fatigue, sleeping 10 hours per night and 1 hour in the afternoons. I had trouble remembering things, as well as the inability to concentrate. I was off balance and frequently missed steps and curbs while walking. As well as often feeling like I was going to black out or faint - never did. With the correct dose everything is much better."

9 / 10
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  • Anonymous
  • March 5, 2010

For Hypothyroidism, After Thyroid Removal "I had my thyroid removed almost a year ago and I can agree that while I have not lost any weight using this drug I have not gained any either. I have had horrible mood swings and lost a great deal of my hair. My Doctor refuses to change the dosage because she says "I'm within normal range" whatever that means? I do feel like I'm experiencing memory loss or having problems concentrating."

5 / 10
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  • Bonny...
  • Taken for 5 to 10 years
  • August 6, 2016

For Underactive Thyroid "For the first few years I had my OB/GYN monitoring my thyroid and adjusting my Levothyroxine… What a mistake! I never felt good and come to find out he was doing it wrong. Not doing the right test to monitor my levels and decreasing my dose when he should've been increasing. I started to see an endocrinologist and WOW! What a difference. He switched me to namebrand Synthroid only (which made a difference) and checks my levels twice a year to make sure I'm on the correct dose. I feel amazing for the first time in years!"

10 / 10
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  • Lucky...
  • August 30, 2016

For Underactive Thyroid "MUST be taken at night - and it absolutely seems to work for me. No more brain fog - and for someone who was always a go getter - the brain fog was devastating. No more night sweats either. Those were the worst."

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  • Anonymous
  • Taken for 1 to 6 months
  • May 27, 2012

For Hypothyroidism, After Thyroid Removal "I had half my thyroid out almost three months ago. Started taking medication about five weeks post-op. I have become depressed and stressed. Everything bothers me and I cannot let it go. I go days without sleeping and live on black coffee. I have the shakes and hate everybody and everything. I cannot rid myself of the stress. I do not know if this is the medicine but that is the only new medicine I have been taking."

2 / 10
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  • Harle...
  • February 26, 2011

For Underactive Thyroid "I've been taking Synthroid since October 2010 for my underactive Thyroid and am also a type 2 Diabetic. It is now February 2011 and things are wonderful. After about two weeks, my mood improved. After 6 weeks I was able to get a haircut (prior to this my hair kept breaking off at the ends) and my hair shines again. I've also lost a total of 15.5 pounds and counting. My doctor says it's because the Synthroid has corrected my metabolism. No bad side effects to date (fingers crossed for the future too). I am on a low dose...25mg. Monday through to Friday only...Weekends off."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • March 30, 2015

For Underactive Thyroid "While it brought the TSH into the appropriate range, the exhaustion, lethargy, constipation, etc. was unbearable. For 20 hours out of the day, felt drowsy, unmotivated and sleepy. This is no way to live. Got on Tirosint and what a difference."

3 / 10
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  • I...
  • Taken for 2 to 5 years
  • August 19, 2012

For Hypothyroidism, After Thyroid Removal "My wife is been taking this medication for about 5 years now. she has terrible paranoia is always in a bad mood also, sleep problems, hair loss and irritation. her doctor test for levels all the time and he tells her she is fine, however I do not agree! She goes out drinking when she gets upset."

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  • LoveN...
  • Taken for 6 months to 1 year
  • July 12, 2018

For Underactive Thyroid "Originally my doctor put me on Levothyroxine when I first had symptoms of hypothyroidism. I continue to have the symptoms and ended up putting on a total of 43 lb! I then asked to see an endocrinologist and Bug them to put me on nature thyroid.. do to my persistence they put me on 82. 75 MCG of naturethroid. After 3 weeks of it in my system, I began to have energy again, stomach aches went away, slept better and was able to work out daily again! My new endocrinologist insisted that Synthroid was better then nature thyroid... So I will switch to Synthroid.. stomach aches and fatigue came back.. Synthroid and Levothyroxine don't help."

3 / 10
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  • Nanny...
  • January 23, 2016

For Underactive Thyroid "Before synthroid I was achy and tired. Now I have headaches...bloating...stomach pain...loose stools and the feeling of being in a fog. I'm only on day 4 of the lowest dose cut in half. I'm stopping it. I was put on it before and it made my heart go to sinus tach but the new doctor insisted I try it again! Hell no! I felt better before the medication!"

1 / 10
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  • Sharo...
  • January 19, 2014

For Hashimoto's disease "I've been on Synthroid for over 15 years due to Hashimoto's Disease and also partial thyroidectomy due to a nodule. For anyone who is on the medication and says they are feeling depressed, tired, etc. check into the symptoms of hypothyroidism/Hashimoto's disease as it may be that your medication is not at the right dose. My doctor considers 'normal' TSH to be between 1 and 3 while the AMA lists it as between 1 and 5. When I am at a 4, I do not feel well and have all the symptoms. DON'T just STOP taking this medication on your own as you can have severe side effects, GO back to your doctor and discuss how you feel. I cannot take the generics as they do not work for me. Only SYNTHROID for me! (I'm on 225 a day!)"

10 / 10
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  • Anonymous
  • June 8, 2010

For Underactive Thyroid "I've been on Synthroid (Levothyroxine) for about a year and a half now. They've changed my dose 4 times so far and I'm currently at 100 mcg. Once they keep me on a dose for a bit, I feel okay, but with every change I have a few annoying side effects. I can say that if you take it every day like you're supposed to, it will work eventually. You have to be patient, it won't make you feel great right away. It took me about 3 months. But it helped with my lethargy, weight and even depression. It's pretty good if you take as prescribed. If you stop taking it suddenly, the effects of hypothyroidism come back pretty quickly and severely so I recommend taking it as your doctor states."

6 / 10
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  • Strong...
  • Taken for 10 years or more
  • August 1, 2015

For Underactive Thyroid "Since being diagnosed with "Hypothyroidism"(1999). 1st was given antidepressents for being tired and gaining weight (eyeroll). Have been on 88mcg's of *Synthroid-daily.My blood work has always come back with my TSH at the HIGH-end of normal. Former Dr retired years ago so no continuum of care (walk in clinic). Recently new Dr suggested we adjust meds to bring down the TSH level. Started with 100mcg *Levothyroxine 5 days & Synthroid 88-2 days a week.In a few months time I suffered some pretty severe side effects-EXTREME dizziness/weakness,lack of energy,mood extremes,weight is either climbing or stagnant,racing pulse/heartrate.We checked levels & now TSH reads at the extreme low end of normal.I'm scared please help."

3 / 10
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  • Dore
  • Taken for 5 to 10 years
  • September 8, 2019

For Hashimoto's disease "So sorry some of you are having this experience with Synthroid. I have been on this medication for 8 years now. When I started out with it, I had many of the same symptoms of all of you for about nine months. During that time I went thru 5 medication adjustments. Started out at 25 mcg , then ended up at 100mcg. Then went to taking the 100 mcg 5 times a week and cutting the pill in half two days. What worked for me is the following: -Take exactly the same time every morning -Do not eat or drink anything within the hour after that -Some medications and supplements interfere with the absorption of it. Take them 4 to 6 hours before or after. This is important because Synthroid is a narrow therapeutic dosing drug. In other words, if your dose isn't just right, you will experience all the negative side effects of both hypo and drug side effects. - If your dr isn't willing to adjust the dose for you like my dr has, find another dr."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.