Synthroid Interactions
There are 239 drugs known to interact with Synthroid (levothyroxine), along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 219 are moderate, and 20 are minor.
- View all 239 medications that may interact with Synthroid
- View Synthroid alcohol/food interactions (3)
- View Synthroid disease interactions (5)
Most frequently checked interactions
View interaction reports for Synthroid (levothyroxine) and the medicines listed below.
- amlodipine
- amlodipine
- aspirin
- aspirin
- atorvastatin
- atorvastatin
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- gabapentin
- gabapentin
- hydrochlorothiazide
- hydrochlorothiazide
- Lipitor (atorvastatin)
- Lipitor (atorvastatin)
- lisinopril
- lisinopril
- losartan
- losartan
- metformin
- metformin
- omeprazole
- omeprazole
- prednisone
- prednisone
- trazodone
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
Synthroid alcohol/food interactions
There are 3 alcohol/food interactions with Synthroid (levothyroxine).
Synthroid disease interactions
There are 5 disease interactions with Synthroid (levothyroxine) which include:
Report options
More about Synthroid (levothyroxine)
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- Reviews (191)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: thyroid drugs
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Tirosint
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Ozempic
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Euthyrox
Euthyrox (levothyroxine) is used to treat hypothyroidism and to treat or prevent goiter. Includes ...
NP Thyroid
NP Thyroid is used for hashimoto's disease, hypothyroidism, after thyroid removal, thyroid cancer ...
Levoxyl
Levoxyl treats hypothyroidism (low thyroid hormone) and treats or prevents goiter. Learn about side ...
Unithroid
Unithroid is used for hashimoto's disease, hypothyroidism, after thyroid removal, myxedema coma ...
Levothroid
Levothroid is used for hashimoto's disease, hypothyroidism, after thyroid removal, myxedema coma ...
Tirosint-Sol
Tirosint-SOL is an oral levothyroxine (L-thyroxine [T4]) solution that may be used in adults and ...
Thyroid desiccated
Thyroid desiccated is taken to replace the body's natural thyroid hormones and is used to prevent ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
