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Xyzal and Tiredness: What Users Say (Page 2)

Reviews for Xyzal

Commonly mentioned side effects
  • Jen...
  • Taken for less than 1 month
  • May 22, 2017

For Allergies "First time using Xyzal last night for allergies. Normally, I take Benadryl, but wanted to give this product a try as it's new OTC. I only took half a pill at bedtime. Yes, my allergic symptoms cleared up, but WOW did it make me tired. I'm thankful I have the day off, as I don't know how I could function at work. I expected some drowsiness, but this far exceeds the effect of a full dose of Benadryl."

7 / 10
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  • MeL...
  • October 9, 2017

For Allergies "I've had such a mixed experience with this drug. On the one hand, it kicked a sinus allergy-induced migraine I had for days that hadn't responded to other medicine. Once I started taking it on a daily basis, however, it made me extremely tired and sore. I tried taking halves, and it isn't so bad that way, but ultimately led to a lupus flare, which made me realize it was having a stronger effect on my body than I'd realized. Now missing work from it. Take with caution!"

5 / 10
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  • Pra...
  • Taken for 1 to 6 months
  • May 30, 2022

For Allergies "I took Xyzal for a couple of months, stopped and restarted this spring. Since restarting, I was getting more fatigued and achy, little by little, with almost a drugged/hungover feeling most every morning. It would take me until late afternoon to feel somewhat functional. I chalked this up to other issues (hormonal, life changes, work stress), but then stumbled upon something that discussed such side effects with allergy medicines. After doing extensive research, I've found these effects are not as uncommon, or random, as they first appeared. After stopping about two weeks ago, I don't have the exhaustion, body/joint pain, and drugged feeling every morning. It has been a marked, and remarkable, difference. Granted, I still have allergies...but I'll gladly take those over feeling like I was 137 years old. I was getting afraid that something else was happening or that if this was just 'aging,' I wasn't going to make it much longer! I'm feeling much better now this medicine is out of my system."

2 / 10
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Frequently asked questions

  • J K...
  • February 14, 2018

For Allergies "Started taking it in 2017 after the owl ads on TV. It does work, and it does produce a mild tiredness hangover effect the next day-though it is less pronounced than Benadryl's next day hangover. I took one tablet a day for a month and started noticing the hangover getting stronger, so I cut down to half a tablet. I started noticing a very quick and aggressive angry response from me to any type of provocation or annoyance-yikes! I stopped taking it immediately after noticing this side effect after 2 months of taking it. I now take a 1/4 tablet with a Mucinex, when allergies flare up, and this seems to work better with no pronounced anger or hangover."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • September 9, 2019

For Allergies "Took Xyzal at 8:00 pm last night, and it is now noon the next day, and I am still having trouble keeping my eyes open. The box warned it could cause drowsiness, but I am beyond drowsy-extremely tired."

3 / 10
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17 Report

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  • UMa...
  • Taken for less than 1 month
  • October 10, 2019

For Urticaria "I felt like I had lockjaw, felt tired and sleepy, my tongue was swollen, I kept pinching the side of my tongue every time I chewed my food, itchy, yellow urine."

1 / 10
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  • Anonymous
  • July 29, 2009

For Allergies "I tried this drug, but it made me very tired. I was so tired and slept for like 3 days until I realized the drug was doing it. So I can't take it, or I'll sleep for 20 hours at a time."

5 / 10
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32 Report
  • pla...
  • March 29, 2017

For Allergies "I suffer from severe allergies and thought I would try something new. I have taken this going on two weeks, and all I feel is tired and sleepy - placebo medication?"

1 / 10
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  • Anonymous
  • September 6, 2009

For Allergies "Works very well to help with my allergies. I recommend use at night, as it did tend to make me very tired."

9 / 10
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24 Report
  • Jim...
  • Taken for less than 1 month
  • April 3, 2021

For Urticaria "Worst antihistamine ever. It clears up sinuses and even some post-nasal drip, but it makes one extremely tired and achy the next day. Not motivated to do anything. I took it 3 days, never again."

1 / 10
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  • Ary...
  • June 4, 2017

For Allergies "I have been taking Xyzal for about a week now, and it appears to have made an improvement concerning my allergies; however, I am feeling overly tired."

7 / 10
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  • Sug...
  • February 20, 2017

For Allergic Rhinitis "Really tired and sleepy throughout the day. I take medicine in the evening."

10 / 10
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  • Joa...
  • Taken for less than 1 month
  • April 16, 2018

For Allergies "This drug made me so tired and a little depressed after 2 doses in 2 days. Also, it dried my eyes so much that I could barely get contacts out, which led to eye pain and infection."

1 / 10
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  • Ano...
  • September 17, 2017

For Allergies "This was prescribed to my elderly mother. After taking it for about a month, she began to have hallucinations, as well as feeling extremely tired. We will make sure she never takes this again."

2 / 10
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  • Deb...
  • May 25, 2017

For Allergies "This product does not help me at all. Do not buy it, waste of money, it just makes you tired."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.