Skip to main content

User Reviews for Xyzal to treat Urticaria

Xyzal has an average rating of 7.4 out of 10 from a total of 41 ratings for the treatment of Urticaria. 71% of reviewers reported a positive effect, while 20% reported a negative effect.

Xyzal Rating Summary

7.4/10 average rating

41 ratings from 44 user reviews.

Compare all 94 medications used in the treatment of Urticaria.

10
29%
9
34%
8
7%
7
7%
6
0%
5
0%
4
2%
3
0%
2
2%
1
17%

Reviews for Xyzal

Windsicle · Taken for 1 to 6 months July 3, 2019

“I have suffered from hives as well as intense itching without rash for 15+ years. It is getting worse with age (I'm 34). Touching random objects, anything laying on or against my extremities, heat, etc. Went to allergist finally as I thought I was having severe food allergies - they diagnosed me with urticaria, turns out I have no allergies, just 'reactions'. I told them antihistamines have never worked for me, but they said with this condition it may be needed up to 4 times a day. I started with zyrtec twice a day, which helped but I was too sleepy. I have been on 1.5 xyzal am, 1 pm for over a month now and am mostly itch free for the first time I can remember. Can't believe OTC medication was all I needed for this endless nightmare.”

9 / 10
Was this helpful?YesNo
Lot · Taken for 1 to 6 months January 26, 2020

“I have a chronic urticaria that is triggered by fluorquinolones. Xyzal works almost instantly to calm the pruritus, however the sleepinss makes me drink five coffees per day to function. Hope I will be able to get off it pretty soon.”

9 / 10
Was this helpful?YesNo
YusY September 2, 2015

“If ever there is an award for the most irritating/embarassing illness, urticaria would (must?) definitely be a contender. Diagnosed with chronic urticaria about a month ago, and suffered immensely (redundancy at play here :). Nothing really worked, until a dermatologist prescribed Xyzal about a week ago. Told to drop all forms of medication - anti-histamines and ALL supplements, among others - and just take Xyzal. Hives acted up on first two days but have been free (almost) of hives for five days. Early days, but keeping fingers crossed that this will be a permanent solution. Will update.”

8 / 10
Was this helpful?YesNo
coriiic · Taken for 5 to 10 years December 9, 2014

“This medication is excellent! I have had horrible angioedema (a type of urticaria where the hives form under the skin) since I was ten years old from an autoimmune disease and have gone through several different medications, but this once has worked the most effectively. And I can tell how well it works because when I forget to take it, the hives show up within about 12 hours after the missed dose and once I remember to take the missed dose, within about two hours, it feels as though I never had angioedema at all.”

10 / 10
Was this helpful?YesNo
alyiov June 4, 2017

“I suffered from hives caused by friction, sunlight, temperature change, exercise, and showering for over 10 years, getting increasingly worse as I got older. I hardly had a life -- I couldn't exercise or go outside without breaking out in painful, burning hives. Claritin, Zyrtec and Benadryl only helped a little. When I was finally prescribed Xyzal by an allergist my life was changed! As long as I take it every day, I rarely get hives. I still get some if I run or am in the sun without sunscreen, but aside from that, I'm free! I am so thankful for Xyzal, and no longer living in fear every day being ruined by hives. The first few days I was drowsy, so I take it only at night.”

9 / 10
Was this helpful?YesNo
Janee · Taken for 1 to 6 months July 13, 2019

“I decided to try Xyzal when I was unable to calm the itching I have. A full tablet seemed to really dry me out. I was thrilled to see the tablets are scored! The this means that it has the same dose on each side of the score. Much greater experience taking half. Lots of people don't know that is reason it is scored. Half a Xyzal helps so much! The cost is better when you have twice the dose in a bottle!! I'm really glad it's available.”

9 / 10
Was this helpful?YesNo
Anonymous September 8, 2008

“I have suffered from hives for almost a year now. I have tried every antihistamine on the market and was almost about to give up ever finding something that could help relieve the hives. Finally my doctor put me on Xyzal and it is the only antihistamine that has ever worked for me. I've tried some other medicines and none of them seem to do anything. Since I have been on the Xyzal I have hardly had any outbreaks and if I do I hardly ever suffer from severe itching and discomfort. I've been taking it everyday now for almost 4 months with no serious side effects. I would recommend that anyone suffering from chronic urticaria try Xyzal.”

9 / 10
Was this helpful?YesNo

Frequently asked questions

Anonymous August 25, 2011

“I have had hives my entire life. I finally saw an allergist and he did tests. He took me off of all medicines and put me on Xyzal. I took the Xyzal three times and I have not had a hive since. Seriously. I had my first hives at 4 months and had hives everyday for forty six years. I do not know what Xyzal did but it fixed me. I stopped taking Claritin and Benadryl and Zyrtec. Took Xyzal for three days. It made me VERY sleepy. I can't even take a normal Benadryl dose without falling asleep, though. I had to take liquid Benadryl, one teaspoon, if I wanted to stay awake. I slept twelve hours with my first dose of Xyzal and about 8 hours with the two successive doses. Then, I never had a hive again.”

10 / 10
Was this helpful?YesNo
patient 712 · Taken for less than 1 month August 10, 2015

“I broke out in itchy red welts that the doctor first thought was insect bites. It continued even after I stayed indoors. I also have alopecia ariata which is auto immune. I took xyzal and after just 2 days, the itching and welts lessened and by day 5 I did not form any more welts.”

8 / 10
Was this helpful?YesNo
Adim7 · Taken for 1 to 6 months July 3, 2018

“Xyzal is horrible. I’ve spent the last 4 years of my life suffering due to side effects of antihistamines. These drugs are all the same thing. They make you feel annoyed, depressed, anxious, exhausted, dizzy, and just like absolute garbage! I thought xyzal, being the “newer and better” drug it was marketed to be, would be the miracle to save my life. However, it wasn’t. This drug is just as bad as the rest, possibly even worse. Also, keep in mind that xyzal is no different than Zyrtec. It’s literally just the left half of Zyrtec, the part of it that actually works. It’s the same drug. If Zyrtec sucks for you, xyzal will too. Honestly I’m gonna go back to claritin. It doesn’t stop my hives completely but I am at least not a psychotic depressed maniac on it.”

1 / 10
Was this helpful?YesNo
VMR · Taken for 1 to 2 years May 12, 2018

“I developed Hives after gallbladder surgery. Benedryl worked on the surface for about 8 months. Then I went to an allergist and she had me stop all meds for allergies. That night I thought I was going to die. Lips were swollen eyes were and I didn't sleep. The next morning was back at the dr. and was nebulized in the office for 4 hours. She prescribed Zyzal 10 mg at night, and Singulair in the morning as needed. Worked wonderfully. I can played around with dosage taking at night. I can go 1 night without it and I have to take it the next night. 72 hours with out a dosage and I will have a breakout start. Told the Dr. that I will take this the rest of my life, and I don't mind.”

10 / 10
Was this helpful?YesNo
Estelle A. February 23, 2011

“It has been 2 years since I've suffered with Chronic Hives. Like many on this board, nothing has worked. After a severe outbreak of hives, and a visit to my Doctor, he put me on Xyzal. I can say I'm about 95% hive free. I still have some hives but they're not as many or as large. It is very early with this treatment to say that it will continue this way. But, for the first time, I am hopeful. I will return to this forum to give updates.”

9 / 10
Was this helpful?YesNo
Anonymous August 16, 2009

“I suffered for a year with Uticaria. I tried steriods and several other allergy medications. To no avail. Finally after seeing many Doctors, one gave me Xyzal to try. The first day I took it I had almost immeadiate relief. My hives, swelling of joints and what I called "attacks" (could not stop sneezing, feeling my throat close and face start to swell up) all but disappeared. I have been taking Xyzal daily for almost 2 years and have experienced no side effects whatsoever. It gave me my life back.”

9 / 10
Was this helpful?YesNo
Anonymous December 4, 2012

“Hives and itchy skin and very bad hand itch that cased to to scratch. I used to get them every other day for 2-3 hours I used to lock myself in the room and itch and itch and itch then. I was told about Xyzal from my father-in-law. Life is so good with Xyzal. I only wish this medicine is known to more people who suffer from itch and hives that make life so painful. But when Medicine like Xyzal is created. It's very good medicine that can cure allergies or itchy skin. I just take one tablet every 2 days and sleep like baby and feel the best next mooring.”

10 / 10
Was this helpful?YesNo
Anonymous October 7, 2009

“I have had Severe Chronic Hives for a little over a year. So many Allergists/Immunologists gave me everything including XYZAL (but once a day combined with other medicines) did very little to help. A Dermatologist said to stop all other and take XYZAL in morning and night and now my Hives are 95% cleared. I'm am at a point were I feel the hives are manageable and I can work without the heavy AntiHistimines that make me so Groggy.”

9 / 10
Was this helpful?YesNo
MLB0609 June 25, 2009

“I have had chronic hives for a year and a half. It's awful. I have been taking Xyzal for almost a year now. Xyzal works to eliminate the itching and rashes, but it makes me very tired. If I take it during the day I feel tired. If I take it before bed I have difficulty waking up and getting started. It also makes me feel down, just not myself. I have not found anything better to help with my rash outbreaks so I do continue to use it.”

7 / 10
Was this helpful?YesNo
Anonymous May 13, 2010

“I have suffered from hives for over 30 years. No medicine helped. I had them for 3 years straight, 24/7. My hives have come back about 4 different times, lasting up to a year. I have been on Xyzal for about 2 months. I take Benadryl, then an hour later I will take the Xyzal. I take Benadryl at bedtime. This is the first time in the 30 years that I feel they are under control. For anyone with chronic hives, its worth a shot. I have no side effects as of yet. They do not make me tired either.”

10 / 10
Was this helpful?YesNo
Sick of Hives... January 22, 2011

“I have been suffering with Auto Immune Chronic Urticaria with Angioedema since August 2010. I am so over these HIVES. I was also diagnosed with a mild case of (ITP) Idiopathic Thrombocytopenia (low platelet count) in August as well. Since then I have been on a roller coaster with these hives. One day I am hive free, the next day I wake up with swollen lips then a few days later my arms, back and legs are covered in hives. Since August I have been on Benadryl, Atarax, Singular, Zantac, Zyrtec, Claratin, methylprednisolone just to name a few. A few days ago I looked on the internet and saw Xyzal. I immediately called my allergist and asked for it. I couldn%u2019t believe that it was $113.99 for 30 tabs. It was worth a try. Today is day number three on the medication and I do notice a BIG difference. I still have a few hives here and there but overall, it is a LIFE SAVER to me. I have not noticed any major side effects so far. I have been a little drowsy and I am shocked at that because NOTHING makes me sleepy. I have a feeling my Hubby will have to put this one in the budget! ”

8 / 10
Was this helpful?YesNo
Anonymous December 9, 2009

“I have suffered with severe hives for more than 8 years. About one year ago my fourth doctor discovered I had H-Pylori. After treatment I remained hive free for almost 8 months. This summer minor reoccurances started back but are controlled with one Xyzal at night, not 100% effective but close to 85%.”

Was this helpful?YesNo
Reborn November 30, 2009

“Within two days of starting this drug my Delayed Pressure Urticaria, DPU, came under control. It controls it so far to about at the 95% level. I had a couple of major flare-ups the first day I took it, but I suspect the levels had not built up in my blood yet. I have had one headache but unknown if this drug caused it. My allergies are also under control. The Urticaria still appears a little but much less in size, scope and no itching or raised welts. No feelings of tiredness for me, in fact it kind of speeds me up. I'm amazed that a cousin of Zyrtec can do so much more. Zyrtec didn't touch the hives before, even when taking up to triple the normal daily dose. If you have hives give it a try.”

9 / 10
Was this helpful?YesNo
Anonymous June 16, 2010

“I started developing an outbreak of rashes all over my body about two years ago. Since then my GP has prescribed the usual antihistamine cetirizine and hydroxyzine. I noticed my rashes didn't subside totally after I took them both, but when I was prescribed Xyzal, I noticed it lowered the inflammation of my skin and the itchiness level was greatly reduced too. Since then I have been taking Xyzal together with Atarax and I find it to be quite effective as a combination. I have been taking Xyzal on a daily basis ever since. My rashes come back sometimes, but I have no choice since there are no newer antihistamine other then Xyzal. My doctor has never prescribed me Allegra.”

7 / 10
Was this helpful?YesNo
Saly71 June 18, 2017

“It has been the only antiallergic that really works for me. I take it every other day. It is just fantastic and so happy that now is over the counter, now I can get the 80 tablets bottle and not deal with insurance and is cheaper than the out of the pocket payment that I used to pay.”

10 / 10
Was this helpful?YesNo
MollieH April 7, 2017

“Have used it only 4 days. The first night I felt quite sedate and went to sleep easily. The following nights were just the opposite Have great difficulty settling down and getting to sleep. I take it about 9 pm and would like to be asleep by 11:00.”

4 / 10
Was this helpful?YesNo
mstaylor December 3, 2009

“My itchy skin due to Psoriasis was reduced by 80% when I started taking Xyzal. Nothing I have taken over the years has come close. It doesn't make me sleepy like Atarax or Benadryl. A great bonus is it works for 24 hours. I'm able to sleep through the night without any annoying itch.”

9 / 10
Was this helpful?YesNo
Anonymous November 20, 2009

“My 16 year old dughter was prescribed this medicine and after two doses became exhausted. She could not remember anything she learned in school. Said it was effortful to walk, although she walked normally. She described herself as feeling like she was in a dream state. I discontinued the drug and within 24 hours she felt normal.”

1 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

Learn more about Urticaria

IBM Watson Micromedex

Symptoms and treatments