Irbesartan and Tiredness: What Users Say

• Bug...
• Taken for 2 to 5 years
• January 30, 2019

For High Blood Pressure "I plan to go off of Irbesartan as soon as possible after reading these reviews. I am a young 71-year-old female and have been on 300 mg of Irbesartan for approximately 6 months after quitting Valsartan. So excited tonight after reading all of these reviews! I feel like maybe I can get to feeling well again! I have had so many stomach problems in the later years since starting Valsartan and even much worse after going on Irbesartan - aching, bloating, burning, and nausea. I have had such horrible foot, hip, and leg cramps also. I get only a few hours of sleep each night. I used to be such a very energetic person and I have been so very tired since going on these medications, maybe even a little depressed. There's so many things I want to get done and I have had such low energy, which is not like me. I have had problems driving at night from the horrible glare of headlights and night blindness. I am, however, so very appreciative of these reviews! Thank you!"

• ren...
• Taken for 5 to 10 years
• September 18, 2019

Irbesartan for High Blood Pressure "I have been on Avapro for 5 years. At first, it didn't control blood pressure. Then the doctor increased the dosage to 300mg. I have noticed over the years depleted potassium readings. My side effects are: I urinate often, I am now having pain in my hands, constant tiredness, overall lack of energy, and lack of interest in things. I am also feeling depressed and irritable. I am going back to my doctor to have me taken off this drug. I feel like the side effects are increasing with more drugs in your body for longer periods of time of taking it."

• Jel...
• Taken for 10 years or more
• March 4, 2016

Irbesartan for High Blood Pressure "I am 63 years old, and inherited high blood pressure from my mother. I have been taking Avapro for about 15 years. Initially, it was 150mg, but recently, as 2 years I have been on 300 mg. Initially, after the increased dose, I had such back muscle/bone pain, it felt as if an elephant had sat on me. My doctor changed my medication to a beta-blocker, but that did nothing to bring my blood pressure down. What annoys me after reading everyone's feedback is I have been struggling with exhaustion for years, muscle pain, lightheadedness when standing, fainting even landing up fainting at work, with the ambulance being called. Not the doctor, nor the hospital mentioned the side effects of this medication."

• Mar...
• Taken for 6 months to 1 year
• January 13, 2019

For High Blood Pressure "I’ve been on irbesartan for 6 months now, and I have found that it really doesn’t help my BP. My values are around 138/85/75. And that is not consistent, sometimes I take it and it could be 135/81/68, and five minutes later it's 143/90/81. I have severe tinnitus, extremely tired, sore muscles, and my joints are hurting, especially my shoulder like I have bursitis. I have neck pain and a weird feeling in my throat all the time. I need to find something else, I can’t do it anymore!"

• Dre...
• Taken for less than 1 month
• September 13, 2018

For High Blood Pressure "I was given 150 mg of this medication for moderate high blood pressure. I’ve never had a negative reaction to any medication until this stuff. While I realize everyone is different, this stuff shouldn’t be allowed on the market. I only took it for 3 days but I can’t even begin to tell you how terrible it made me feel. Anxious, extremely tired - yet inability to sleep at all (up 100% of the night), brain fog, feeling like a zombie, and weird buzzing feeling. This is a terrible medication and I don’t suggest anyone take it."

• Joh...
• Taken for 1 to 2 years
• July 31, 2018

For High Blood Pressure "I've been taking irbesartan for about 1 year. I went from taking 300mg to 150mg, and now I break the pill in half. My blood pressure is not consistent. I'm always tired, have muscle aches, ankle swelling, headaches, palpitations, experience dry cough periodically, blurred vision, night sweats, and uncontrollable anxiety. I wish I had read the comments prior to starting taking the pills."

• Sca...
• June 13, 2012

Irbesartan for High Blood Pressure "I have taken Avapro 300mg for over seven years for BP 140/98. Since I began my annual physical exams consistently show BP 170/110. Like many other reviews, I initially found that Avapro 300mg, taken first thing in the morning, made me feel very tired and sleepy. As a policeman, I considered it dangerous to be on the job in this condition. The solution was to take it at night, just before bedtime, when I want to be sleepy. By morning, I wake up feeling great. By the end of my stressful day, I think my BP may be a little higher (understandably), but by then I am home to relax. I have, at times, within an hour of taking the dose, had 'blind staggers' after I stand up quickly or dozed off without realizing I had, but no other side effects."

• Oll...
• Taken for less than 1 month
• September 6, 2015

For High Blood Pressure "I have only been taking this drug for two weeks, but despite the fact that my BP is definitely down, I have been ultra lethargic, my eyes have become very sensitive to bright lights, my back is aching, my bursitis has flared up again, my tinnitus is really loud, and I have been very arthritic for the last week. Where is my quality of life?"

• 2bl...
• May 6, 2010

Irbesartan for High Blood Pressure "I have been taking Avapro for more years than I care to remember. It did not do the trick in lowering my blood pressure alone, so a diuretic was added to the mix. I get so tired I can hardly stand to stay awake. I am so lazy, I don't feel like doing anything, and I don't even care. I started researching and found this site, perhaps this tiredness is from Avapro. I will talk to my doctor."

• 2bl...
• May 6, 2010

Irbesartan for High Blood Pressure "I have been taking Avapro for more years than I care to remember. It did not do the trick in lowering my blood pressure alone, so a diuretic was added to the mix. I get so tired I can hardly stand to stay awake. I am so lazy, I don't feel like doing anything, and I don't even care. I started researching and found this site, perhaps this tiredness is from Avapro. I will talk to my doctor."

• hus...
• January 2, 2010

Irbesartan for High Blood Pressure "I have been taking Avapro for at least 2 years and I'm noticing muscle weakness, tiredness, dizziness, and an overall feeling of laziness. It seemed so subtle that it just kind of happened, and I believe it is the Avapro. I also get swelling of joints, wrists, knees, and ankles. Also, several cases of painful gout. My blood pressure is about 135/85. I'm going to go off Avapro for a week and see if all these painful symptoms go away. I only take 75mg a day. I would never recommend this medicine. I play tennis 2 times a week but the pain seems to be too much."

• jud...
• December 12, 2009

Irbesartan for High Blood Pressure "After 1.5 years of taking 150 mg of Avapro to control my blood pressure, I realized that what started out as fatigue developed into my becoming almost non-functional shortly after taking it... feeling totally exhausted, sleepy, and poor balance issues. Didn't control pressure well either."

• Anonymous
• Taken for 10 years or more
• July 12, 2012

Irbesartan for High Blood Pressure "I am a 33-year-old who has experienced high blood pressure ever since starting work after graduating from University. I also have a Thyroid condition and always just assumed this was the entire cause of my tingling in the hands & feet and constant issues with tiredness. The tingling sensation predates the Avapro, but the ongoing issue with tiredness could also be attributed to the Avapro. I have been on Avapro for the last ten years. I am off Avapro now as my blood pressure is now normal."

• Des...
• Taken for 5 to 10 years
• January 24, 2018

For High Blood Pressure "I am so glad I found this site. I have been on irbesartan for several years and have had a dry cough, sweating, tiredness, increased urination, trouble sleeping, sometimes shortness of breath, muscle cramps, and general lack of interest in things. After reading these reviews, I feel sure that these symptoms must be down to the irbesartan. My doctor put me on to this drug because strokes are in my family. I'm going to stop taking the tablets whilst monitoring my blood pressure."

• Anonymous
• November 30, 2009

Irbesartan for High Blood Pressure "I have been taking Avapro for 5 years and I don't like it so am looking for another drug. My GP thinks if the side effects are bearable, don't change anything. I don't like the dizziness, cold feet, dry throat, and tiredness it produces. It has also depleted my potassium levels and I wonder if the arrhythmias I have been having are related to prolonged use."

• Ear...
• December 23, 2007

Irbesartan for High Blood Pressure "I have been taking 150mg Avapro for 3 months, and the doctor is raising the dosage to 300mg. Since starting this medication, I do experience more than usual tiredness and muscle ache, especially in the neck and shoulders. It has lowered my blood pressure, sometimes too low in the 80/45 range."

• Ton...
• March 9, 2010

Irbesartan for High Blood Pressure "I've been taking 150mg samples for almost 2 weeks. The medication (Avapro) increased my tiredness levels, which are quite high with fibromyalgia and Sjogren's day-to-day. Normal anxiety is heightened as well and is almost unbearable in its severity. I am experiencing no lessening in my blood pressure readings. I plan to discuss this medication with my PCP during my scheduled follow-up visit. It's quite expensive too."

• Roy...
• October 7, 2016

For High Blood Pressure "Yes, my BP went down a little, but the side effects were so dreadful I had no choice but to give this drug up after 4 wks. Almost immediately, I began to feel lethargic, and within days, despite also making me feel bloated, I lost my appetite, and the reflux set in big time. Eventually, my urine turned a dark yellow, I often felt light-headed on getting up, and my energy levels dropped so low that I could barely put one foot in front of the other on a trip to the city (I can normally walk/jog 3 miles for exercise). I came off them 3 days ago, and my energy levels are nearly back to normal, but, because my liver was having difficulty processing the drug, its bilirubin levels remain off the scale (nearly 10 times the norm), and I now have jaundice."

• Tfr...
• December 28, 2017

For High Blood Pressure "This medicine has not lowered my blood pressure much in 4 months. I feel weak, tired, very hard to breathe, like I have asthma, which causes me to panic and get anxiety, and when it's cold out, I have chest pains walking fast, headaches, and some kind of weird swollen feeling in my throat and tonsil area all day that seem to ease up if I take a Halls menthol, but soon comes back. It also feels like I have angina, and on the days I forget to take my pill, I feel wonderful. No side effects. I can breathe, no swollen feeling, nothing. I guess it's time to look for a different med. Losartan did almost the same thing but not as intense."

• Ric...
• March 4, 2008

Irbesartan for High Blood Pressure "I initially used 150mg a day with no actual results in lowering BP. Doctor recommended a combination with Felodipine 5mg and Metoprolol 50mg, and the combination produced results in lowering my BP to 115/75 on average. Side effects are tingling in the palm of my hands and excessive tiredness. I will test discontinuing irbesartan, which produces the unwanted side effects."

• ros...
• April 16, 2009

Irbesartan for High Blood Pressure "I started taking samples of 150 mg Avapro and have been using it for 4 weeks now. With the medication, my blood pressure runs 135/78, which is okay for a 72-year-old. I am now having knee and one hip pain and have noticed I am much more tired than usual. I am going to try some relaxation, slow breathing exercises, and will see if I can come off the Avapro."

• alm...
• August 29, 2009

Irbesartan for High Blood Pressure "I have been on Avapro for about 6 months. My blood pressure is better, however, I am extremely tired. I have tried taking the medicine (300 mg daily) every other day. I am going to try 150 mg and see if I tolerate it better. I do not want to try another new medicine."

• Kar...
• January 24, 2011

Irbesartan for Diabetic Kidney Disease "I've been taking Avapro to prevent diabetic kidney disease, as I only have half of one kidney left after two bouts of kidney cancer. So far, so good. The Avapro has lowered my blood pressure also - sometimes goes a little too low, which is when I feel tired. Other than that, I have no noticeable side effects. However, my doctor will have to find some other medication to protect my remaining partial kidney because my insurance company won't pay for Avapro anymore - even though my doctor says nothing else works as well."

• Off...
• Taken for 1 to 2 years
• July 7, 2021

For High Blood Pressure "I took 75 mg to control spikes over 200 systolic. It did that. It also made me tired and mildly depressed. Then I started losing my ability to recall memories and experiences, which gave me nightmares. It was so bad I felt my personality was going away. I finally quit, and I started remembering things within two or three days. It made me emotional. My blood pressure is dangerously high, but none of the other drugs are a good alternative. They denied the fact that a physical problem could cause this, but my tests showed adrenal gland, kidney, and liver problems, as well as small blood vessels and a narrowed artery. Surely, repairing this stuff is a better option for us patients than certain dental causes by drugs."

• Jan...
• Taken for 10 years or more
• September 20, 2021

Irbesartan for High Blood Pressure "I have taken Avapro for years, and lately, my BP is over the top, so put on zircol. All this has been too much. I feel a new change is needed, as I have tiredness, sore muscles, bones, in fact, whole body. They say exercise, how, when you are so tired? When the pump goes to 230, I know I am in trouble. Thank you for your review."