Irbesartan and Fatigue: What Users Say

• Bug...
• Taken for 2 to 5 years
• January 30, 2019

For High Blood Pressure "I plan to go off of Irbesartan as soon as possible after reading these reviews. I am a young 71-year-old female and have been on 300 mg of Irbesartan for approximately 6 months after quitting Valsartan. So excited tonight after reading all of these reviews! I feel like maybe I can get to feeling well again! I have had so many stomach problems in the later years since starting Valsartan and even much worse after going on Irbesartan - aching, bloating, burning, and nausea. I have had such horrible foot, hip, and leg cramps also. I get only a few hours of sleep each night. I used to be such a very energetic person and I have been so very tired since going on these medications, maybe even a little depressed. There's so many things I want to get done and I have had such low energy, which is not like me. I have had problems driving at night from the horrible glare of headlights and night blindness. I am, however, so very appreciative of these reviews! Thank you!"

• ren...
• Taken for 5 to 10 years
• September 18, 2019

Irbesartan for High Blood Pressure "I have been on Avapro for 5 years. At first, it didn't control blood pressure. Then the doctor increased the dosage to 300mg. I have noticed over the years depleted potassium readings. My side effects are: I urinate often, I am now having pain in my hands, constant tiredness, overall lack of energy, and lack of interest in things. I am also feeling depressed and irritable. I am going back to my doctor to have me taken off this drug. I feel like the side effects are increasing with more drugs in your body for longer periods of time of taking it."

• Ger...
• Taken for 1 to 6 months
• March 23, 2019

For High Blood Pressure "Been on Irbesartan for about 6 weeks and am experiencing fatigue and sleeping a lot during the day. Also experience some dizziness and feel like I am in a fog. I split the pill in 2 and take 75 mg per day. My numbers are better but it is not a miracle and they do fluctuate. I am at a crossroads as of what to do because my quality of life is not good. It has been several years since I tried a blood pressure med and the last time I went through several before giving up. Since I recently had an AFib episode I thought it was time to settle on one. I don’t think any will agree with me so don’t know what I am going to do."

• Ste...
• Taken for 1 to 2 years
• January 7, 2020

For High Blood Pressure "Have been on this drug irbesartan for 1 1/2 years. Although it has reduced my blood pressure, the side effects were intolerable. Shoulder tendinitis, severe joint and muscle pain, urination issues, weight gain, swelling in my mouth, and fatigue. Am 70 years old but felt like I aged ten years. Stopped taking it 28 days ago. Taking Bystolic now and all of these side effects have gradually gone away. Irbesartan is awful, would not recommend it for anyone."

• jud...
• December 12, 2009

Irbesartan for High Blood Pressure "After 1.5 years of taking 150 mg of Avapro to control my blood pressure, I realized that what started out as fatigue developed into my becoming almost non-functional shortly after taking it... feeling totally exhausted, sleepy, and poor balance issues. Didn't control pressure well either."

• Mar...
• June 10, 2010

Irbesartan for High Blood Pressure "I have been on Avapro for about a week and do not really have any noticeable side effects. Beta blockers are much worse for making you tired. Avapro seems to have helped my blood pressure a little, but not as much as my beta blockers. The only thing I noticed is a dry cough, but I am not sure if that is the Avapro or allergies. I take 100 mg of CoQ10 once a day, and that has helped with the side effects of the beta blockers, and it may be helping me not see side effects of Avapro. For anyone who feels fatigue and takes blood pressure medication, try CoQ10, it's got low risk for side effects and tends to help bring back energy levels that are partially caused by depleted CoQ10 when you take blood pressure medication."

• Roy...
• October 7, 2016

For High Blood Pressure "Yes, my BP went down a little, but the side effects were so dreadful I had no choice but to give this drug up after 4 wks. Almost immediately, I began to feel lethargic, and within days, despite also making me feel bloated, I lost my appetite, and the reflux set in big time. Eventually, my urine turned a dark yellow, I often felt light-headed on getting up, and my energy levels dropped so low that I could barely put one foot in front of the other on a trip to the city (I can normally walk/jog 3 miles for exercise). I came off them 3 days ago, and my energy levels are nearly back to normal, but, because my liver was having difficulty processing the drug, its bilirubin levels remain off the scale (nearly 10 times the norm), and I now have jaundice."

• Bet...
• Taken for 1 to 6 months
• October 29, 2018

For High Blood Pressure "Just switched to calcium channel blocker type meds over this type. Valsartan (now recalled) and irbesartan both caused weird nausea issues (mostly exertion-induced - couldn't exercise in any way without feeling nauseous) and general malaise after about 2 months of use. Lightheadedness kicked in at about 4-5 months, and started to get significantly worse after about 1-2 weeks of manifestation."

• Mon...
• Taken for 1 to 2 years
• May 15, 2023

For High Blood Pressure "Taking this medication as the combination irbesartan + hydrochlorothiazide. After graduating from 150 mg to 300 mg dosage, I find this medication does no longer control my BP. Side effects are fatigue, stomach pain, and nausea. Unfortunately, I can't take calcium channel blockers as an alternative because of the painful side effects of edema."

• Med...
• Taken for 1 to 6 months
• September 24, 2014

For High Blood Pressure "Controls blood pressure great, but having side effects like constipation, gout, leg cramps, sleepiness, and general fatigue."