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Irbesartan Dosage

Medically reviewed by Last updated on Apr 28, 2021.

Applies to the following strengths: 75 mg; 150 mg; 300 mg

Usual Adult Dose for Hypertension

Initial dose: 150 mg orally once a day

Maximum dose: 300 mg orally once a day

Usual Adult Dose for Diabetic Nephropathy

Target maintenance dose: 300 mg orally once a day

Use: Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (greater than 300 mg/day) in patients with type 2 diabetes and hypertension.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Dose Adjustments

Volume and/or salt depleted patients:
-Initial dose: 75 mg orally once a day


-FETAL TOXICITY: If pregnancy is detected, discontinue this drug as soon as possible. Drugs that act directly on the renin angiotensin system (RAS) can cause injury and death to the developing fetus.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Hemodialysis: Initial dose: 75 mg orally once a day
Peritoneal dialysis: Data not available

Other Comments

Monitoring: Monitor serum potassium and renal function periodically.

Patient advice: Females of childbearing age should be informed of the consequences of exposure to this drug during pregnancy; ask these patients to report pregnancies as soon as possible.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.