Imipramine User Reviews & Ratings (Page 3)

Brand names: Tofranil

Imipramine has an average rating of 7.3 out of 10 from a total of 79 reviews on Drugs.com. 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Imipramine

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Cro...
Taken for 1 to 6 months
May 8, 2024

Imipramine for Depression "Started with 25mg of Tofranil and worked our way up to 75mg. It has been very effective for my depression/anxiety. At first, it made me a little drowsy, but that is no longer the case. I take it midday now. Blood pressure and pulse are within the normal range. No side effects besides a slight increase in appetite."

10 / 10

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2 Report

Was...
May 27, 2019

For Depression "This drug does something that affects one's entire body. I'm far more worried now that my heart will stop than about the depression that this med was given for. Nearly 45 hours since the last dose and I still can't feel my skin. Horrible, horrible drug."

1 / 10

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13 Report

Shr...
Taken for 2 to 5 years
November 10, 2020

For Depression "Imipramine - started it way back in 1982 for clinical depression and took it for 5-6 years. It gave me sleep paralysis and hypnagogic hallucinations, waking and lucid dreams too. I remember telling my psyche about the sleep paralysis (SP), he didn't know why it was happening. Of course, back then, nobody knew what to call it, and I couldn't find out anything on my own until the early 2000s on the internet. Go figure. Occasionally, I'll still have an episode of SP, under stress. The medicine was great for my depression and ADHD, mucked up my dream life though. Not worth the risk if I had to do it all over again. I did enjoy the waking dreams though and the OBEs."

7 / 10

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9 Report

jse...
Taken for 10 years or more
September 18, 2021

For Panic Disorder "People are so different! I've been on Imipramine/Tofranil now for 44 years. It literally saved my life and career. Endogenous (from within) not Reactive Anxiety/Panic/Depressive Disorder from my mom set in around 19 years old. Periodically, I would quit only to get slammed and take months to get better again. Then I tried the new stuff, Prozac."

10 / 10

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4 Report

Imi...
Taken for less than 1 month
November 13, 2022

For Primary Nocturnal Enuresis "Side effects are horrendous. I would rather wear a pad! Side effects: hot flashes, neck pain, muscle spasms, decreased sensation left hand/arm, dizzy, hypotension when standing, and no instruction about weaning off."

1 / 10

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3 Report

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Kat...
Taken for 1 to 6 months
January 26, 2021

For Irritable Bowel Syndrome "I started taking the 10 mg of imipramine in September 2020 for my IBSD. I was told to take it at night because it makes you drowsy. I had the total opposite reaction. It kept me up at night and did not make me drowsy at all. I ended up switching to take it in the morning instead. By November, I noticed that the low dosage was not helping much with my IBSD. My doctor upped my dose to 25 mg, and I started having horrible night sweats. I was waking up every hour at night drenched in sweats. Other than that, this medication really worked for my stomach when the dose was at 25 mg. I wish I did not have this horrible side effect!"

7 / 10

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5 Report

Rin...
Taken for less than 1 month
January 5, 2024

For Depression "I have started imipramine. I am just a little doubtful about most of the medicine, especially anti-depressants (SSRIs), causing bad psoriasis and acid reflux. So, I am trying imipramine now. In a time duration, I will let you know the feedback."

8 / 10

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2 Report

HRW...
Taken for 10 years or more
February 23, 2025

For Panic Disorder "Dramatic and long-lasting suppression of panic disorder with very low dose Tofranil: 10-25 mg QD. No apparent side effects at this low dosage, but full benefit. Can be taken QHS to avoid early morning panic attacks. Dosage may vary from person to person."

9 / 10

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0 Report

Kam...
Taken for less than 1 month
February 17, 2016

Imipramine for Depression "Waste of 75 bucks. My mood only increased slightly, and in exchange I got terrible bouts of dizziness and vertigo. Most of the time I felt like I'd been shot with a tranquilizer dart. Horrible experience. After only a week or so, I started to get nausea as well, so I had to stop. I regret spending money on this med."

2 / 10

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16 Report

Anonymous
April 26, 2010

Imipramine for Depression "Best and least expensive. Came off Celexa because of side effect. Be patient, it works in about 3 weeks."

10 / 10

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113 Report

Joc...
January 27, 2011

For Irritable Bowel Syndrome "Great for irritable bowel syndrome, but I've gained a lot of weight."

7 / 10

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48 Report

Dun...
April 17, 2008

For Pain "I have been on imipramine for over 2 years and found it good for pain relief combined with gabapentin. The only problem I have encountered is weight gain, as it tends to increase my appetite."

8 / 10

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52 Report

Jus...
Taken for 2 to 5 years
August 16, 2024

For Depression "This is an old medicine, but for me, it works so much better than any other antidepressants."

10 / 10

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3 Report

Lil...
Taken for 1 to 2 years
March 1, 2021

For Depression "Imipramine reduced my symptoms of depression significantly. It worked very well in my case."

10 / 10

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11 Report

Sam...
August 1, 2013

Imipramine for Panic Disorder "Nightmares, hard to sleep."

4 / 10

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28 Report

Che...
Taken for less than 1 month
September 17, 2016

For Panic Disorder "Helps with the panic disorder. But I haven't slept in 3 days. Is this medication a stimulant?"

4 / 10

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20 Report

Jus...
Taken for 5 to 10 years
September 21, 2024

For Panic Disorder "I feel in my case, and I have bad panic disorder, that this medication works just as well as benzos do."

10 / 10

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2 Report

Jus...
Taken for 5 to 10 years
September 6, 2024

For Depression "I think, for me, this is the best medication of the antidepressants that works best for me."

10 / 10

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2 Report

Pat...
Taken for 1 to 6 months
February 28, 2022

Imipramine for Depression "I have been on it a few months and feel great. Was put on this for IBS and depression. Been great so far!"

9 / 10

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6 Report

ric...
Taken for less than 1 month
December 5, 2022

For Primary Nocturnal Enuresis "Terrible constipation on the lowest dose. Miralax did not even help. Very bad dry mouth also."

1 / 10

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3 Report

Not...
December 6, 2016

For Panic Disorder "Very bad side effects on day 6, and I have to stop taking. Nausea all the time. Headaches. Dizziness. Nervousness. Tired constantly. On a very low dose."

1 / 10

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12 Report

Anonymous
March 10, 2023

For Irritable Bowel Syndrome "Great. It's better than amitriptyline in case of side effects, i.e., confusion, sedation, etc."

8 / 10

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2 Report

Liv...
Taken for 5 to 10 years
February 9, 2021

For Pain "I started on imipramine 25 mg, 6 years ago. I’m now up to 150 mg and it has worked great until the last month."

10 / 10

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4 Report

Spe...
February 12, 2017

For Panic Disorder "Did not work, only made me very tired."

7 / 10

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9 Report

Ajm...
August 16, 2019

For Depression "Very bad. Less effective. More side effects. Not good for adults."

1 / 10

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6 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.