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Golimumab and Tiredness: What Users Say

Brand names: Simponi, Simponi Aria

Tiredness: mentioned by 10 users (6.5%)

Based on user experiences from 155 Golimumab reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 10.3%
pain 6.5%
tiredness 6.5%
dizziness 5.8%
psoriasis 5.2%
headaches 4.5%
itching 4.5%
rash 3.9%
swelling 3.9%
blurred vision 3.2%

Reviews for Golimumab

Commonly mentioned side effects
  • V V...
  • Taken for 2 to 5 years
  • October 2, 2020

For Rheumatoid Arthritis "I have been on this for about 5 years and have had RA for 40 years and tried lots of medications. But this one works for me the best. I also take Methotrexate with this, and I have been free from illness over the past 3 years. I am only tired the week that I get the infusion, and then I am fine after that. Glad to be able to move like I want to most of the time."

10 / 10
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31 Report
  • gre...
  • Taken for less than 1 month
  • May 11, 2017

For Rheumatoid Arthritis "I had my first infusion today. No ill effects with the exception of exhaustion...additional, that is, as I already am sleeping 16 hours per day. Not sure how a person is supposed to make a living with this advanced RA. I am hoping that Simponi will resolve that in the near future. I will let you know when things start to work and I can return to the land of the living."

1 / 10
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31 Report
  • Qwa...
  • February 3, 2017

For Rheumatoid Arthritis "Yesterday, I got my 4th injection in 4 months at home by a nurse! I think it's working very well so far... I have taken many other types of medicines over 7 years with big side effects for RA. I have had Ulcerative Colitis for 15 years and took some meds for that. Because of side effects, I began a very stringent diet (specific carbohydrate diet). I eventually got better, and all UC symptoms stopped. Years later, I went off the diet and was soon reduced to suffering immensely with undiagnosed RA symptoms. I believe my diet contributes to my symptoms. I know food chemicals can cause inflammation, and I know UC is a cousin to RA. I come from generations of alcoholics and am recovering for 27 years. Sugar is a deadly and strong addiction. Today, I was lethargic."

9 / 10
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28 Report

Frequently asked questions

  • Chr...
  • Taken for 1 to 6 months
  • January 4, 2020

For Psoriatic Arthritis "Was doing fine for about 12 weeks. Then I broke out with a whole new form of palmoplantar pustule psoriasis, and my regular plaque psoriasis came back almost vengefully to the point where my skin feels like it is burning. I had my first infusion in August, then again the second one 4 weeks later, and by the middle of my 8-week stretch was when these rashes happened. My first three days after the infusion, I experienced vomiting and extreme tiredness, but overall I felt fine. The second infusion was pretty much the same, but then all this happened. I am so sore on my hands and feet it feels like I am walking or touching broken glass. I have to wear vinyl gloves to keep the moisture on my hands and keep my feet wrapped with non-stick gauze and taped and covered so I don’t develop a secondary type of infection from something else. I can’t take the pain, so my husband has pushed me to hire a cleaning lady to do my housework because all I am able to do is lay around. This is no way to live."

1 / 10
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18 Report
  • Anonymous
  • Taken for 1 to 6 months
  • March 17, 2022

For Rheumatoid Arthritis "I started Simponi infusions. Just recently, my first infusion was fine, made me a bit tired, but no side effects and no effects at all. My second infusion was 3 weeks ago. I again was tired after the infusion, but I was more tired than usual. I started not feeling real great. The next day, I felt even worse. I believe every side effect that this drug has, I had: fever, cold chills, nausea, extremely fatigued, headache. My whole body has and still is swelled up 2 times more than normal, having trouble breathing. I then ended up with a sinus infection and then pneumonia. Let me say that I have been dealing with RA/Fibromyalgia for the past 23 years. I have been on everything and anything that is available. Suffice to say, nothing has worked for me. However, I never had any side effects to this magnitude with the others. I am glad this works for others and was really hoping to finally get some relief, but I guess my body is rejecting this medication, so I feel I had better listen to it."

1 / 10
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11 Report

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  • Tuc...
  • August 9, 2016

For Rheumatoid Arthritis "I have had 3 infusions, and I am tired all the time and just want to sleep. My vision has also been more blurry. I understand the immune system can be lower on Simponi. I now have shingles on my face, and I had the shingles vaccine two years ago. I have had RA for 33 years, and Plaquenil has helped me more than anything as far as stiffness and pain. I have been taking it for at least 20 years. I also take Celebrex and methotrexate."

2 / 10
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24 Report
  • dre...
  • Taken for 1 to 6 months
  • February 20, 2023

For Rheumatoid Arthritis "I had my first infusion and was totally exhausted after it. Within two days, though, I felt fine. My hands are not as stiff, and I can feel a difference in my feet. I am getting my second infusion this week and hope it continues to improve my rheumatoid arthritis symptoms."

6 / 10
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7 Report
  • Han...
  • Taken for 1 to 6 months
  • September 22, 2019

For Psoriatic Arthritis "I received Simponi Aria infusions from 12/2018 to 6/2019. I’ve had 4 UTIs, the last infection on 9/2019 went to my kidneys. I was hospitalized with sepsis. Now I’ve been referred to a hematologist due to high myelocytes. I always feel sick, tired, weak... I’ve also been prescribed Lipitor for extremely high cholesterol. I’m a vegetarian and eat healthy. I’ve never had these problems prior to Simponi Aria infusions."

1 / 10
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14 Report
  • rrs...
  • December 5, 2017

For Psoriatic Arthritis "I was on Remicade infusion for 7 years, I had wonderful results for 6 years, with PSA flares slowly creeping back in the 7th, but not unmanageable. Rheumy switched me to Simponi. After 2 injections, while my skin is still clear, the PSA is raging. I am in terrible pain. I spoke to my Rheumy once, and she said to give it a chance. Calling her again this morning. The pain and exhaustion are debilitating and affecting every aspect of my life. I asked her about Taltz and Cosentyx, but she wanted to keep me on a TNF blocker. I'm ready for change."

1 / 10
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13 Report
  • Ani...
  • Taken for 1 to 6 months
  • July 1, 2022

For Ankylosing Spondylitis "Used for psoriatic arthritis and ankylosing spondylitis. Seriously multiplied my pain by at least 10, psoriasis was also much, much worse than I’d ever had it previously. Extremely tired, asleep more than awake, terrible pressure felt on the top of my head daily, stuck with it for 5 months in the hope it would settle. No such luck in my case… could say it was worth trying, however, it really, really wasn’t. Wish I never used it at all."

1 / 10
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4 Report

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