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Ezetimibe for High Cholesterol User Reviews (Page 4)

Brand names: Zetia

Ezetimibe has an average rating of 3.8 out of 10 from a total of 137 reviews for the treatment of High Cholesterol. 24% of reviewers reported a positive experience, while 62% reported a negative experience.

Reviews for Ezetimibe

  • Marga...
  • Taken for 6 months to 1 year
  • August 5, 2021

Zetia (ezetimibe) "I was diagnosed with PAD and given statins which caused severe brain fog and confusion to the degree that my spouse though I had dementia. I changed to ezetimibe to reduce high cholesterol, but even though it is not listed for Zetia I still get the brain fog, although not quite as bad, I am afraid to stop taking them, has anyone suffered the same effects? I am also taking clopidrogal and high blood pressure medication. I am 79 years old."

3 / 10
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24 Report
  • debs
  • Taken for less than 1 month
  • November 9, 2019

"My Dr. warned me that I may get stomach problems on ezetimibe, but I wasn't expecting the runs for hours on end and stomach pain. I've stopped it as I'm not sleeping, and I'm constantly burping, and it tastes awful. I messed up my bed and clothing."

1 / 10
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33 Report
  • bob
  • Taken for 6 months to 1 year
  • December 17, 2020

Zetia (ezetimibe) "I started taking Ezetimibe in Feb. 2019. I cannot tolerate statins. After 10 months, I started to develop joint pain, muscle weakness, a runny nose, and was very tired. I checked my blood pressure. It was 213 over 120. I decided that Ezetimibe could be the problem. I stopped taking Ezetimibe. After 2-1/2 days, my blood pressure dropped to 152 over 94. I feel 100% better. There is a question that my liver could have been damaged."

1 / 10
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27 Report

Frequently asked questions

  • Milag...
  • Taken for 1 to 2 years
  • December 6, 2019

"My doc believed my LDL and total cholesterol were too high. I was on Simvastatin 40 mg. He added a script for 10 mg Ezetimibe. Three months later on Simvastatin 40 and Ezetimibe 10, my total cholesterol improved from 216 to 116. LDL improved from 137 to 46. I was on a Paleo diet (no fruit) before and after Ezetimibe. Now all cholesterol measures are well within normal range."

10 / 10
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32 Report
  • Sitinin
  • Taken for 2 to 5 years
  • February 22, 2018

"Was on Zetia 10 mg daily for four years. Underwent numerous scans, testing, ultrasounds, and vascular studies to determine why I was having severe leg cramping every single day (worse at night). I discontinued Zetia by myself, and my legs had a 100% return to normal. Unable to take statins due to joint pains but was assured this med was not the same."

2 / 10
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39 Report

Are you taking this medicine?

  • JJano
  • Taken for less than 1 month
  • November 4, 2020

"I was on Zetia for a month but my hip burned so I stopped, much like other statins I had tried. I tried it again later and after a month both my hips burned. I stopped Zetia and the burning improved. It has been 6 months and my right hip still burns, and sometimes my left. I am done with statins. No drug is worth side effects like this. I will exercise more."

1 / 10
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26 Report
  • Mare
  • August 1, 2020

"Been taking ezetimibe 10 mg about 3 weeks. I do get occasional diarrhea, but my biggest problem is the bloating. My stomach looks like I'm pregnant, and I hate that feeling. I don't have any other symptoms."

5 / 10
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27 Report

More FAQ

  • Meena...
  • Taken for 1 to 6 months
  • November 1, 2021

"I have been on statins for the last 4years. Was placed on Crestor last dec and I had serious adverse effects like dizziness, loss of balance by taking just 2 times later placed back on Lipitor 20mg and then since 9 Sept. Lipitor was reduced to 10mg and Ezemitib 10mg was added. Now I have severe joint and muscle pain with mood swings which I can't explain. How often should liver function tests be taken especially when I have cholecystectomy done? What other options are there to reduce high LDL? With no family history of diabetes I now have high levels of HBA1C 6.5-7.2 thanks to statins. Can anyone reading this reply me? I will be very thankful. Take care all Statin users."

1 / 10
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20 Report
  • Melanie
  • Taken for 1 to 6 months
  • August 5, 2024

Zetia (ezetimibe) "8/2/24 My experience with Zetia has been unexplainable. My numbers were very high, and now, after being on it for 3 months, they are very low. So low I had my doctor do another blood test because I thought the test results were wrong. The second test, done a week later, was even lower. Now I am concerned they will get too low. All statins I was put on caused severe cramping: arms, legs, feet, hands, under my rib cage, back. The only side effect I have with Zetia is possible cramping in my forearms when I stretch and my calves. I also have had hair loss. Now taking Rogaine to see if that helps. I am 75 years old, so lots of complaints may be from just getting old."

10 / 10
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2 Report
  • Cindy
  • Taken for less than 1 month
  • May 20, 2019

"My cholesterol is/was at 235, and through a Doppler, discovered my left interior carotid artery is 100 percent occluded, but got somewhat lucky with some strong collateral arteries. My doctor immediately put me on statins...a big no-go on all of them, each one I tried (5) had horrible side effects immediately. Fog-like state, shortness of breath, muscle cramps, depression, it was terrible. One of my sisters was put on Zetia with no side effects, and her cholesterol went from over 300 down to 80. I begged my doctor to let me at least try it, and I've just passed the 1-week mark with just a couple of small side effects: tingly legs twice and bloating. So far, I love this ezetimibe, however, the proof will be in 2 months when my cholesterol is rechecked. I am a 65-year-old female."

8 / 10
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30 Report
  • Barbara
  • Taken for 1 to 6 months
  • August 2, 2021

"Extreme weakness after taking it 2 months. Then extreme hunger but unable to eat much. After stopping for 7 days, all symptoms stopped. PA said it could not be causing my symptoms because they did not appear at first! I stopped any way and after 7 days I am almost OK."

1 / 10
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19 Report
  • GCano
  • August 11, 2020

"I have been taking Ezetimibe, generic for Zetia, for one year with no side effects. With drug RX card I pay $25.00 every 90 days. My collesteral is down to 200 from 238, I still have to little good cholesterol but its better than the pain I get with Statins."

7 / 10
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23 Report
  • Rick
  • Taken for 1 to 6 months
  • July 27, 2019

"I am on Ezetimibe 10 mg together with Simvastatin 20 mg for four weeks. In the meantime, I stopped Fenofibrate 134 mg. It seems effective to reduce LDL-Cholesterol by 25%, total cholesterol by 30%. Don't know why my triglyceride level was cut in half from 200 to ~100. So far, don't have much side effect, but will watch in the next 3 months."

6 / 10
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27 Report
  • Aggies
  • Taken for 6 months to 1 year
  • June 13, 2024

Zetia (ezetimibe) "I took 10mg of Zetia for high cholesterol for a period of time. Later, I needed heart surgery and was off of it for a period of time. When I resumed the medication, I realized how bad it made me feel, even at a low dose, nothing specific, just general fatigue."

5 / 10
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3 Report
  • Dennis...
  • Taken for 6 months to 1 year
  • October 9, 2016

"I was reading this blog with interest. I'm a Canadian. You are being ripped off in the U.S., I am sorry to say. I am on 5 mg of Crestor and 10 mg of ezetimibe, and I do not have insurance. In Canada, our social health insurance pays for the doctor but not prescriptions unless you are a senior. The cost of these two drugs together is just under $20.00 per month. Yes, not $200.00, but $20.00. I suggest you vote to put pressure on the drug manufacturers to reduce their pricing structures. And by the way, I have tolerated both with no side effects, and my cholesterol numbers for total are very low. My cardiologist is happy, and so am I."

10 / 10
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36 Report
  • Lilypad
  • Taken for 2 to 5 years
  • April 29, 2019

"After having a TIA (transient ischemic attack), I was put on Avandia, which works well. Now I've been given ezetimibe to go with it, and the pain in my legs hurts. Every night I'm tired with headaches all the time. Thinking of dropping it. PS I have swollen ankles too."

4 / 10
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26 Report
  • Steve
  • Taken for 1 to 6 months
  • March 10, 2021

"Sore shoulders, and neck pain. Taking this with a statin and I stopped the ezetimibe after two months. It has been two weeks off the drug and still sore, although not as bad, read that it can take up to two months for your muscles to heal."

1 / 10
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19 Report
  • Michele
  • Taken for 6 months to 1 year
  • December 4, 2018

"I wasn’t sure if I could stay on Zetia at first because my blood pressure was lower than usual (78/56), and I had shortness of breath with extreme fatigue. I secretly took only half a pill and half of my blood pressure medication for a while (not recommended). Almost a month later, everything leveled out, and I’m now taking a full dose of both meds with none of the problems listed. I had a lipid panel at the 4-month mark, and my values were all normal, and my LDL dropped 28 points. Best of all, recent lab work shows my liver enzymes as normal, and this was the first medication that didn’t elevate them into the triple digits. I have a bit of back pain along the spine, but nothing major. I’m not sure if it’s the Zetia or just me. Unless it gets unbearable, I’m gonna stay the course. $30 for the generic 90-day supply with insurance. Very pleased so far."

10 / 10
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26 Report
  • LensD...
  • Taken for 1 to 2 years
  • April 4, 2024

"I had elevated LDL but a good level of HDL. I take this medication every other day or just before meals that might be overly fatty. It has brought my LDL down 30 points and my total is now under 200. I have had no side effects."

10 / 10
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4 Report
  • Mik
  • November 3, 2020

"Have been unable to tolerate statins so doc recommended Zetia. The headaches from Zetia are intolerable. I am stopping them. If I don’t I will end up damaging my kidneys by taking too much ibuprofen just to get through the day."

1 / 10
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18 Report
  • Beeth...
  • July 2, 2019

"Has lowered bad cholesterol and raised good cholesterol , but - Not sure if ezetimbe ( 10 m.g. ) or other medications . Feel completely exhausted , can not tolerate statins ( pain ) Changed PCP's ( a Endocrinologist put me on this medicine + Synjardy X-R + amiloride < due to low potassium) also Blood Pressure medications - Lisinopril 20 mg + Amlodopine Besylate 10 mg ? Over medicated ? Have appointment with PCP tomorrow to discuss . Had very recent Metabolic Profile + Hgb A1C = 5.7 so good BP - 127/67 pulse 67 I take BP medication Lisinopril and Amlodopine Besylate at night as too tired if take in day . I take Synjardy and Ezetimbe and Amilirodine in morning , from Endocrinologist last July and great diabetic control med- diet and Home testing NOTE I have Lost > 40 + pounds since August 2018 and dropped from 44 waist to 36-38 I am a male - Yes I adjusted diet but not that radical , Help ? Panic ? Will post > But (IMO ) medication ('s ) cause of fatigue. ?"

7 / 10
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22 Report
  • Ali...
  • Taken for 5 to 10 years
  • October 6, 2023

"I added Zetia, 10mg, to my 40mg daily Crestor, and it drastically improved my HDL (I was routinely around low 40s, and with Zetia, it went to mid 50s). My LDL was also improved (was 120+/-, and with Zetia, it went below 100). I have had no side effects with either of the medications."

9 / 10
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6 Report
  • RJPKe...
  • Taken for less than 1 month
  • October 24, 2017

"Reduced LDL by about 25%, good. But made me feel terrible, disrupted my already tenuous sleep. I tried it 3 times, same result each time. Too bad, as it works to reduce LDL. Need to try something else."

3 / 10
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24 Report
  • TMano
  • Taken for less than 1 month
  • July 5, 2018

"Starting taking ezetimibe 10mg on 7/1/18. Diarrhea and pain in left side of back by 7/4/18. Taking this along with Simvistatin. Can't continue on the ezetimibe with the back pain especially so will stop until my Dr. & I can figure out another alternative as the Simvistatin 20mg alone not doing it."

1 / 10
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22 Report
  • JonP
  • Taken for 10 years or more
  • November 13, 2021

"Tc was 320. Was on statins and zetia for 10 years til I decided to try whole food, plant-based diet (WFPB). TC dropped to 146, TG:60,APOB:86. Wanted to get APOB down under 70. Worked brilliantly. I’ve NEVER had a reaction to Zetia and am only too happy to be back on it. I consider arterial health as being a prime longevity factor and want to ensure no hardening from any causes."

10 / 10
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11 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.