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Ezetimibe for High Cholesterol User Reviews (Page 3)

Brand names: Zetia

Ezetimibe has an average rating of 3.7 out of 10 from a total of 133 reviews for the treatment of High Cholesterol. 23% of reviewers reported a positive experience, while 64% reported a negative experience.

Reviews for Ezetimibe

  • jack
  • Taken for 6 months to 1 year
  • April 18, 2019

"I put up with night pains, for the first 6 months, now I have chest pain and arm pains when working and moving my arms. Memory and concentration seem to have become an annoyance. Just know, when you suddenly stop using ezetimibe, the side effects do not suddenly stop."

2 / 10
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46 Report
  • Georg...
  • Taken for less than 1 month
  • September 17, 2020

"I am a 68 yr old female. 4 days ago I started this drug ezetimibe with Rosuvastatin, because of diabetes 2 and heart problem. I immediately experienced severe stomach pain, bloating, gas, nausea, diarrhea, light headed, painful urination and muscle cramping. As of today I will cease the use of this drug, pain in lower abdomen is horrendous. I just looked up the side effects of this drug and all of the above are listed!"

1 / 10
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36 Report
  • BANGIE
  • Taken for 2 to 5 years
  • October 6, 2014

Zetia (ezetimibe) "Combining the Zetia with low dose Atorvastatin has produced good results with my cholesterol numbers. My Cardiologist added it to my regimen about 4 years ago and it has not added any side effects other than in the wallet. "

9 / 10
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74 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • November 11, 2021

Zetia (ezetimibe) "I am in perfect health except for my cholesterol and my numbers and remain the same for 15 years after the second day of taking Zetia I knew I would destroy my health. I felt like my face has been beat by baseball bat, I was sick with fever chills and had labored breathing. I flushed the bottle down the toilet and went online to these patient testimonials to discover the side effects that are not mentioned in the guidelines. I have had a nasty sweat all day today. I cannot wait for this horrible drug to get out of my system. Why would I take something that's going to clog my sinuses when I can't breathe and I have clogged sinuses or take something that's going to give me respiratory distress. I always get respiratory illness if I'm sick."

1 / 10
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26 Report
  • molly
  • Taken for less than 1 month
  • February 11, 2021

Zetia (ezetimibe) "I was put on zetia when I could not take statins because of severe muscle pain. Three weeks in I started having pain in my elbow and both shoulders I stopped the medication so I ended up taking it less than one month. Six month later after stopping the medication and still the pain did not go away"

1 / 10
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31 Report

Are you taking this medicine?

  • Sue
  • Taken for 1 to 6 months
  • October 2, 2018

"My doctor recommended I try ezetimibe and said I might experience some joint/muscle pain. Within 10 days, I had severe lower back pain and needed physio and a chiropractor for 3 weeks of therapy. I stopped this medication and returned to my doctor who assured me that this medication does not cause localized pain in one specific area. So I agreed to restart ezetimibe and within another two weeks had severe knee swelling and pain and again my doctor does not believe ezetimibe is the cause. However from reading some of the above comments, it sounds as though others have experienced similar localized pain. I now have to get an X-ray of my knee and more medical treatment. I’m not 100% sure ezetimibe is the cause but I’m not convinced it isn’t either."

2 / 10
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  • Regre...
  • Taken for less than 1 month
  • September 6, 2020

"Don’t take this medication. I started taking it 2 weeks ago and have lost function in my left shoulder. I wish I had caught on sooner but now even though I haven’t taken the drug for a few days, I’m still wearing a sling and can barely use my left arm. I’m not sure if the damage is permanent."

1 / 10
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More FAQ

  • Patti
  • Taken for less than 1 month
  • October 9, 2019

"Doctor put me on this to lower cholesterol, I'm a person with 3 heart stents second day I took it got all kinds of side effects, trouble breathing stomach pain and terrible swelling headache cramping of muscles. Don't understand why he would do that as it says doesn't mix well with blood thinners, stay away from this drug if possible, very dangerous "

1 / 10
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  • Nicole
  • Taken for 1 to 6 months
  • May 26, 2023

Zetia (ezetimibe) "46yrs old. I had high cholesterol of over 300 and have been taking Lipitor 40mg for 7 years. A Cardiologist added Zetia 10mg to my Lipitor. To bring down my overall cholesterol. Starting taking it on July 7th, 2022. I didn’t have side effects right away. By August I developed a pain on the left side of my neck that over time nothing I took would get rid of the pain only dulled it. During that time my menstrual cycle was not consistent and I became very fatigued over time. To the point, I was exhausted by the end of the day. Which caused me to gain weight. In November 2022 I just stopped taking it to see if my neck pain would go away and two weeks later it was gone. A month later my menstrual cycle was back to normal and within the last 30 days, I’m not as fatigued as I used to be while working. Yes, it did lower my LDL and brought my overall cholesterol number down within 3 months. But keep in mind I have had high HDL and perfect triglycerides numbers. Prior to taking this and still do!"

3 / 10
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  • GaryBB
  • August 24, 2017

"Multiple statins over years caused severe muscle aches in lower body, fatigue, stomach pain and scary loss of memory and focus. Took months but dramatic improvement after stoppage. Have talked to many people with identical experiences. Been on ezitimibe two months. Experiencing pain and swelling in left hand, wrist and forearm, body fatigue, sudden short bouts of liquid diarrhea, waking up during night sleep absolutely drenched and awash in perspiration, loss of muscular strength and increasing loss of mental focus. Talked today to a friend having comparable symptoms. Stopping this drug immediately."

2 / 10
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51 Report
  • Great...
  • August 5, 2016

Zetia (ezetimibe) "Dropped total number down 86 points teamed only with red yeast rice supplements. 10 mg per day with dinner. I live in Phienix so can't tell if Zetia causing sweat or Phx heat but it has worked great. Very active life and no known side effects. Mail prescription plan costs 40.00 for 90 days."

10 / 10
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56 Report
  • GranE
  • Taken for less than 1 month
  • October 18, 2020

"Had high cholesterol for over 40 years & runs in family. Statins for 12 months took a year out of my life even when given different ones the side affects were intolerable. Recent blood test showed still too high LDL so prescribed ezetimibe as told not a statin and only side effects in less than one percent of population and possible only side effect would be diarrhea. Day 1, All good Day 2 some diarrhea in morning, by afternoon headache which got worse all through night and into day 3. Day 3 pains in upper shoulder, legs, nausea and still really bad headache. Ginger tabs eased the nausea but nothing fixed the headache and awake all night. Day 4 worse than day 3 so have stopped. I have always reacted to prescription meds, always get the side affects but would rather have a quality of life with high LDL than feel like this. Have not heard of any other alternatives."

1 / 10
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30 Report
  • Rob
  • Taken for 1 to 6 months
  • August 16, 2021

"Started taking Ezetimbe about two months now terrible side effects to start with but just thought my body would get used to it ,what a mistake as I never felt so ill in my life . Shoulder pain, stomach pain, chest pains ,most of all its the feeling of being ill fuzzy head not just with it . Stopped taking now for two days still getting symptoms hope I can get back to my normal self soon . I would rather have high cholesterol than take this pill that makes you feel like rubbish."

1 / 10
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  • Charlie
  • Taken for 1 to 6 months
  • April 28, 2019

"Ezetimibe caused serious insomnia problems with resulting tiredness all day. I also had a constant low level anxiety and mild depression while taking it. My brain didn't function as well- forgetting to do routine things (like put the milk back in the refrigerator as an example). It took me a while to realize that it was the medication causing these symptoms because they can be caused by simple increases in stress, etc."

1 / 10
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  • Jake
  • Taken for less than 1 month
  • July 12, 2021

"After 2 or 3 days I became so dizzy and or lightheaded. Didn’t think it was the new med, I went to ER thinking it was a sinus infection and was prescribed amoxicillin for 7 days nothing, as I was the same if not worse. Went to Primary’s office and was told to discontinue ezetimibe and what do you knowI getting better. I’ll be reading this site much more before starting new meds.."

1 / 10
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  • Silky
  • Taken for 6 months to 1 year
  • May 22, 2020

"I’ve been taking Ezetimibe 10mg every day for 8 months and have good results. My doctor tried a statin before that made me sick, I was dizzy and couldn’t think clearly - raising my blood sugar over 300 for a week. I’m type 1 diabetic 20 years and had to take this option and am grateful no longer having complications. My HDL and LDL are above average now. I’m also on a low carb mostly vegetarian diet."

10 / 10
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31 Report
  • EAano
  • Taken for less than 1 month
  • October 5, 2020

"I have decided to stop taking this horrible medicine, I been taking this medicine for my cholesterol, and my joints, hands, legs, and feet hurt so much that I can even sleep. This medicine should not be prescribed if the quality of life is going to be this poor."

1 / 10
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  • Janie
  • Taken for less than 1 month
  • March 27, 2023

Zetia (ezetimibe) "I was hoping this would work as I am statin intolerant. I began belching nonstop and had chest pain. I have never felt like this before. Quitting my one cup of coffee a day and anything else known to aggravate GERD had no impact. I also had leg pain starting from the buttocks all the way down through the arches of my feet. I rarely get ocular migraines but started to get them frequently. I’m off of it and feeling much better. A glass of wine or coffee does not bother me. It was the medication."

1 / 10
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  • Marmite
  • July 3, 2021

"I started on ezetimibe 4 weeks ago after trying 5 different statins. Since starting this med I keep telling my doc I get very dizzy and sleep for England I.e slept 15 hrs today and extreme dizziness. Think I will leave tablet off from tonight as I can’t tolerate the way I feel. Since my heart attack 2 years ago I have not felt right all down to medication think I’d rather have a shorter life with no meds as all these meds cause more problems. Does anyone else feel dizzy constantly on these meds ?"

1 / 10
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  • Rubba...
  • Taken for less than 1 month
  • September 12, 2018

"I am a Diabetic, so of course the doctors automatically say I have to be on cholesterol medication. My LDL is only 116, so just over the within range for the lab tests. Tried statins in the past and the cramps were unbearable. Well after 4 days on this drug and I feel like I have not slept in weeks. I have lost 5 pounds in the short time, the severe diarrhea is keeping me up at night, and I have developed a rash on my chest. Also my joints and muscles are really sore, and my chest feels very tight. Like I could not do anything that would elevate my heart rate. Also feel dizzy and lightheaded, but that could be because I have not slept much due to running to the bathroom multiple times at night. I will be stopping medication as of now! I do not have a gallbladder, and they state in there consumer guide that it is safe for patients who do not have gallbladder. If you do not have your gallbladder, really think hard before trying this."

1 / 10
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  • bob
  • Taken for 6 months to 1 year
  • December 17, 2020

Zetia (ezetimibe) "I started taking Ezetimibe in Feb. 2019. I can not tolerate statins. After 10 months I started to develop joint pain, muscle weakness, runny nose and was very tired. I checked my blood pressure. It was 213 over 120. I decided that ezetimibe could be the problem. I stopped taking Ezetimibe. After 2-1/2 days by blood pressure dropped to 152 over 94. I feel 100% better. There is a question that my liver could have bee damaged."

1 / 10
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  • Riodosa
  • Taken for 5 to 10 years
  • August 4, 2018

"I have been on this number of years - maybe 7. I think the Ezetimibe was effective on reducing the cholesterol as designed however, I have had bouts of diarrhea for years like my stomach explodes and out it comes. The doctors have not come up with a cause and/or a solution. Lately I have reason to believe it is caused by the Ezetimibe that I take. It seems to come on me about 2 or 3 hours after I take it. Anybody else have this problem?"

6 / 10
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37 Report
  • Marga...
  • Taken for 6 months to 1 year
  • August 5, 2021

Zetia (ezetimibe) "I was diagnosed with PAD and given statins which caused severe brain fog and confusion to the degree that my spouse though I had dementia. I changed to ezetimibe to reduce high cholesterol, but even though it is not listed for Zetia I still get the brain fog, although not quite as bad, I am afraid to stop taking them, has anyone suffered the same effects? I am also taking clopidrogal and high blood pressure medication. I am 79 years old."

3 / 10
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21 Report
  • Flygirl
  • Taken for less than 1 month
  • February 23, 2018

"I was taking the name brand Zetia for many years after trying 5 different statins that caused leg cramps that had me jumping out of bed at night and no way to stop the horrendous pain. No, pickle juice and hot showers didn't work. Things were going well with the Zetia until my insurance company refused to cover the drug this year and said I had to take the generic ezetimibe. What a disaster! It was like doing a colonoscopy prep every day. I couldn't leave the house because I was constantly running to the bathroom with severe diarrhea that lasted about 8-10 hours until the drug wore off. It made it impossible to even go to work. I couldn't eat anything without it running right through me (that's how it controlled the cholesterol--nothing stayed with you). Frankly, I'd rather take NOTHING than go through that again."

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  • ejn
  • Taken for 1 to 6 months
  • March 18, 2017

"I have used this for a few months as I cannot take a statin due to muscle pains. During this period I developed a stiff shoulder that later progressed to a frozen shoulder. Worse, I had problems with focussed thinking, and because of my lack of focussed thinking I only noticed this at 6 weeks. As I am a teacher, I immediately quit using it. I was lucky this happened in the school holidays. I have no idea what it did for my cholesterol, as the second side effect I noticed was such that I felt unable to continue it."

2 / 10
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42 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.