Is ezetimibe a statin drug?
Can you take ezetimibe with other cholesterol lowering drugs?
Medically reviewed by Melisa Puckey, BPharm. Last updated on Oct 18, 2020.
No, ezetimibe is not a statin drug, it is from the drug class cholesterol absorption inhibitor
Ezetimibe and statins are cholesterol lowering drugs that work different ways to reduce cholesterol.
- Ezetimibe has its effect in the small intestine where it blocks cholesterol from being absorbed, so there is less cholesterol being delivered to the liver.
- Statins lower the amount of cholesterol and lipoproteins that the body produces, by inhibiting an enzyme called HMG-CoA reductase. Statins also increase the LDL receptors on liver cells which increases the amount of LDL-cholesterol that can be absorbed out of the bloodstream and then the LDL-cholesterol is disposed of by being broken down.
- Ezetimibe is not a statin medication, it is a cholesterol absorption inhibitor.
- Ezetimibe,fenofibrate and statins are cholesterol lowering medications.
- Ezetimibe can be taken together with statins or fenofibrate as their cholesterol lowering effects are complementary.
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