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User Reviews for Cymbalta

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Cymbalta Rating Summary

User Ratings
10
   
19%(11)
9
   
16%(9)
8
   
14%(8)
7
   
9%(5)
6
   
9%(5)
5
   
9%(5)
4
   
0%(0)
3
   
4%(2)
2
   
7%(4)
1
   
16%(9)
6.3/10 Average Rating
58 Ratings with 52 User Reviews

What next? Compare all 61 medications used in the treatment of Major Depressive Disorder.

Reviews for Cymbalta to treat Major Depressive Disorder

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"In the last couple of months since starting this med, I've noticed I've felt and acted a lot better. My caregiver has remarked how much better I'm doing. I'm even thinking about leaving the house, which is very unusual for me. No side effects that I've noticed but I rarely have any. So far so good. Hope it will work for me for a long time."

mommymouse (taken for 1 to 6 months) July 10, 2018

6 users found this comment helpful.
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"I’ve been on this med for 4 years (I’ve been on every dose but I’m now on 60mg) and have tried a number of other medicines including: Lexapro, Paxil, Wellbutrin, amitriptyline, and Abilify just to make a few. I was diagnosed with MDD, GAD, and Panic Disorder in 2011 (when I was 18). I’ve been on a lot of drugs and this one has been the best one for me so far. I mean of course I’m not cured or anything but it makes life much easier and it doesn’t make me as pessimistic and gloomy about life. I still have bad days and I’m still struggling with apathy and things like cleaning and showering but I do it and my life isn’t as bad as it could be so I really can’t complain.* *disclaimer: I’ve been in outpatient treatment twice and go to therapy once a month so that plays a roll as well I think."

   
7.0

Jujubee93 (taken for 2 to 5 years) June 19, 2018

3 users found this comment helpful.
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"Cymbalta worked quickly to reduce depressive symptoms, ie. Deep sadness, lack of motivation, adheadonia,etc in that I would rate it a 10. I had been on it about 1.5 yrs & was taking 120 mg /day when my Dr didn't call in my Rx for a week. I had no idea why I felt so icky. I called my neighbor and he diagnosed me with cymbalta withdrawal via the Internet .Nobody told me that this drug has physically addictive properties. The symptoms abated once I took 60 mg. So I stuck with 60 mg a day & called my Dr for a taper. It is awful ! To all those that have just started Cymbalta know this - you have @ least a 50/50 chance of having " discontinuation syndrome " on dose reduction. Read the site on Eli Lilly's hx with Cymbalta lawsuits. Read everything you can before you take your next dose The world is so unpredictable. Do you want to carry the burden of addiction &withdrawal in a time of crisis, insurance changes, medical illness or injury ? I don't."

   
1.0

Mary S April 16, 2018

7 users found this comment helpful.
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"This medicine gave me nothing but brain zaps and nausea. This medicine has a very short half life so make sure to take your meds within 20hrs or you will feel sick all day long. Getting off this medicine was worse than getting on. It took me months to get the nausea, brain zaps, insomnia, and headaches to stops."

   
2.0

Zae (taken for 1 to 2 years) April 8, 2018

2 users found this comment helpful.
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"I have tried so many medications for my depression and anxiety and nothing had worked. I was hospitalized as I was feeling suicidal and the Dr thought right away that Cymbalta would work for me. It did! I also suffer from migraines which have improved as well. Starting up on the med was okay, but after 4 weeks I developed insomnia that lasted six months and finally went away. The meds also make me crave sweets in the evenings and I never had a sweet tooth before. I’ve heard other similar stories. My anxiety has also improved and I am currently tapering off of Clonazepam. I continue to get healthier on this medication. It offered me the crutch I needed to take care of myself, practice coping techniques learned in therapy, and get better."

   
9.0

Zenbound (taken for 1 to 2 years) February 9, 2018

4 users found this comment helpful.
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"I have Gen. Anxiety and Major Depressive Disorder. I took this med 5 days. I would not recommend this to anyone. The side effects were unbearable. I'd talk about mine but they already cut them. They rushed the testing time for side effects and rushed thru FDA. This med is also found addictive so come down dose slowly if you need to stop. God bless to those ppl that it helped."

clueless18 (taken for less than 1 month) January 11, 2018

4 users found this comment helpful.
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"For the past year and half I have been on Cymbalta. This medicine has made a significant amount of difference. It helps a lot with depression and nerve pain. Working with a dedicated nurse practitioner and medical team they make a difference. She is a pleasure to work with and provides options for her patients. The Cymbalta reduces the nerve pain. It helps with depression and anxiety. Thank you for the awesome recommendation and support."

   
10

Josh D (taken for 1 to 2 years) October 10, 2017

13 users found this comment helpful.
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"Was prescribed Cymbalta 1.5 years ago to treat Major Depressive Disorder. Helped lessen the sadness caused by depression, but also made me numb emotionally. Decided to taper off of Cymbalta, while being advised by my physician, and the withdrawal symptoms were terrible. Currently still on 30mg (down from 120mg) and going to look for easier ways to withdraw. Would not recommend Cymbalta to anyone, as I feel I was doing better before I started the medication, and the withdrawal symptoms aren't worth it."

   
3.0

Zack T (taken for 1 to 2 years) September 9, 2017

9 users found this comment helpful.
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"I was prescribed Cymbalta in August 2016. I was told it was one of the antidepressants that had little side effects. This drug made me extremely tired, almost lethargic, & I gained 20 lbs a matter of 8 months, despite eating healthy. I am a very health conscious person. I lost a lot of hair. My husband actually asked me if I was pulling my hair out. If I missed a dose of this medicine, I literally felt like I had the worst flu ever. I had the chills, diarrhea, achey, etc. I just got off this medicine but am extremely depressed from all of the effects of it. I am now larger than I have been since being pregnant & my hair is thinning. I warn people to avoid Cymbalta at all costs!!!!"

Anonymous (taken for 6 months to 1 year) May 31, 2017

17 users found this comment helpful.
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"although OK when I first stated to take this 30mg caps, then increased to 60 mg daily...after some years , I am showing more signs of tiredness, confusion, anxiety, hot flushes, and forgetfulness and general mental decline, and still get depressed, among symptoms....am truly concerned about this, as is my Husband and children (as I am not yet 65 yrs old)...and have always been in good health. I do not smoke, do drugs, and very seldom drink alcohol...."

   
6.0

Anna - Rose S May 15, 2017

11 users found this comment helpful.
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"I started this drug back in the summer-ish of 2016. I was given 30 mg, which, let me say, was [at the time] The Holy Grail. I lost a bunch of weight, because it had helped me feel good enough to stop emotionally eating. Started on 60 mg, and it felt like a placebo. I accidentally stopped taking it for about 5 days and experienced physical withdrawals which I wasn't warned about until I googled. I'm currently weening myself off of it, because I refuse to be a slave to this or any other drug."

   
2.0

purple reign (taken for 6 months to 1 year) April 13, 2017

12 users found this comment helpful.
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"I married a great man. I put this man through hell . I'm 34 was 32 had a hysterectomy and here came menopause. I was living hell. I felt every bad feeling you could possibly feel. For no reason. Finally this Feb 2017 I snapped. I don't remember much other than trying to kill myself. I almost lost my family. I reached out for help my Dr put me on 30mg then 60 now 120. The 1st day I felt brand new. My face was numb but that's it. Everything is brighter better warm and I have love in my ❤ Thank you for saving me!"

   
10

Kansas Kim March 6, 2017

37 users found this comment helpful.
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"I was diagnosed with depression when I was 18 (now 31). I began taking Prozac, which was effective at first, but then it plateaued. My doctor prescribed me 60mg of Cymbalta back then, and that dose has been effective ever since. For a short time, my doctor lowered it to 30mg, and I became severely depressed. Once it was raised back to 60mg, I was a whole new person again. I highly recommend this miracle drug!"

GinaBoBina February 3, 2017

26 users found this comment helpful.
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"Have been on multiple antidepressants in my lifetime, all were duds. They caused weight gain, fluctuating moods, extreme sadness. My doctor has recently prescribed me 20mg of Cymbalta, after 2 weeks I will switch to 40mg, 20mg in the morning and 20mg in the evening. After reading reviews online I am hopeful, as everyone has reviewed it mainly positive. Currently after being on it for 5 days I am experiencing MAJOR nausea. I can barely breathe without wanting to throw up everywhere. Thankfully, a coworker has given me "phenergan", which is used for nausea, but it is a prescription pill. I called my doctor and explained that this has helped, and she refused putting me on another prescription just to treat the side effects of Cymbalta. SOS!"

   
5.0

Gigi F (taken for less than 1 month) January 10, 2017

11 users found this comment helpful.
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"I am a 33 year old female recently prescribed 20mg of Cymbalta for Major Depressive Disorder, Generalized Anxiety Disorder, and PTSD. This medication has rapidly stabilized my condition and greatly contributed to better mood regulation. In less than a week, Cymbalta alleviated suicidal thoughts and my level of distress in response to triggers. Intrusive memories and fearfulness have been very minimal. Daily crying episodes are significantly reduced. Short term side effects included nausea, sharp decrease in appetite, and fatigue. Ongoing side effects are dizziness, afternoon drowsiness, loss of appetite, and weight loss. Dizziness is manageable if I drink water throughout the day. No sexual side effects experienced while on this drug."

   
8.0

Anonymous (taken for less than 1 month) December 27, 2016

27 users found this comment helpful.
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"Cymbalta was a real game changer for me after a lot of trial and error with other antidepressants. It was prescribed to me in 2006 during a major depressive episode in my early twenties that required inpatient hospitalization. The results were remarkable. In a span of 24 hours, I had much greater mood regulation and was not ruminating on negative thoughts. Cymbalta was also helpful in developing healthy eating patterns after a period of binge eating. The appetite suppressing effect made it easier for me to modify portions and lose the weight I'd gained. I took Cymbalta for two years. The only lasting side effect was afternoon and evening tiredness. Titrating off the medication went well except for some nausea that eventually resided."

   
8.0

Anonymous (taken for 2 to 5 years) December 16, 2016

37 users found this comment helpful.
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"This was the most helpful antidepressant for me (previous were Prozac, Wellbutrin, Lexapro, and Effexor). I was getting along with people, working out regularly, and had no side effects except for a bit of drowsiness depending on when I took it. Eventually I was diagnosed with having a bipolar component and so now I'm taking Lamictal with it. Overall a pretty potent and good medication."

   
8.0

roger_d_1989 (taken for 2 to 5 years) November 7, 2016

15 users found this comment helpful.
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"I can not take this medication due to the fact that you use dyes, I am allergic to them and can not take them, yet manufactors seem to think there is no problem with using dyes. Why not use natural materials like beet juice for color, get away from the dyes, they are not healthy for us."

   
1.0

Brandies September 6, 2016

9 users found this comment helpful.
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"Do not give to people under 18 the black box warning is true I was put on this when I was 16 (i'm 19 now) and it made me want to kill myself to the point of hospitalization. Even though that side effect may be rare it does happen. Do not think it won't happen to you or your child because it's so rare. Im blessed to still be alive today. It makes you messed up beyond words. Should never be given to young kids. It ruined my teenage years. It ruined it!!!I am dead serious too!!!"

   
1.0

Macyyyy (taken for 2 to 5 years) July 9, 2016

12 users found this comment helpful.
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"I had been on Zoloft for 8 years before it just stopped working. Doctor switched me to Cymbalta and I was very fortunate that it worked, really well for 6 years. Unfortunately, my insurance company switched approval for this to the generic version, which absolutely is not the same. It slowly started losing efficacy. So my doctor had to increase my daily dosage (on the generic version) from 60 mg to 90 mg. At 60 mg, I had didn't have sexual side effects, but I did at 90 mg, which was not acceptable to me. So back down to 60 mg I went. Now I'm having "break through" symptoms again: anger, irritability, lack of interest in things. I'm not sure what I'll do, but I'm pretty sure I have to switch meds completely again."

   
9.0

Time for a new med (taken for 5 to 10 years) June 21, 2016

20 users found this comment helpful.
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"So I gave it an ok review score because it did make feel less depressed. However, as a whole I think cymbalta is bad for you and can lead to terrible health consequences. The side effects I experienced while taking the drug (30 mgs for 6 months) were horrible and I gained a ton of weight which didn't help the initial cause of me wanting to take the drug - depression (when you don't feel confident your less happy, what can I say). A few lbs to become a happier person is ok, but it really made me gain weight and also made me tired, nausea, sweaty, and experience muscle spasms. Along with this, withdrawing was horrible. I wish big pharma would be less money hungry and focus on creating effective medications with reduced side effects."

   
6.0

cymbaltaisbad June 8, 2016

11 users found this comment helpful.
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"I took this medication for a year and a half,it worked great for my anger issues but did very little for my depression...It also worked well for my fibromyalgia...The down fall for me was feeling like a zombie 24/7,to the point of not even having energy to clean my house,have a shower daily or even brush my teeth...I just didn't care about anything at all...Not a good way to live "

   
5.0

Janeypooh (taken for 1 to 2 years) May 29, 2016

19 users found this comment helpful.
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"I started cymbalta at 24 and I'm now 32... I changed to them after I had my first born but from 18 years old I was on Luvox! Yes first year or so I felt the cymbalta helped me a lot. More then the Luvox ever did. But for about a while now I really have noticed the bad things.... I get a migraine if i haven't taken one by 6pm. I get snappy and angry if I just miss one day... Last yr i Kept forgetting to take my scripted into get filled. After a few days I was yelling and crying and dug myself in a hole! I couldn't get out of bed the war in my head was so bad! My fam even called doctors on me because they were that worried.... The doctors advice was to go back on my cymbalta and start councelling! I want to change it but I hate it!"

   
2.0

LizaMac84 April 30, 2016

13 users found this comment helpful.
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"I have had depression as far back as I can remember, diagnosed with GA and major depression along with PTSD due to two life changing events I went though. I've tried zoloft (did nothing ) Effexor XR ( Made me sleep 24/7) Celexa ( caused SEVERE anxiety attacks) and just started Cymbolta, on day 7 and I can't believe how much better I already feel at 30mg 1x day. I also just had 2 major back surgeries and am learning to walk again at age 35, yet despite my trials, I feel happier, positive, lowered anxiety etc. First day I did have severe throwing up spells, but that's gone, low appetite still but a good thing for me, INCREASED sex drive & sleep like a baby. I take it at 8 everyday. Good luck, everyone's different!"

   
10

Abelslove80 (taken for less than 1 month) April 8, 2016

48 users found this comment helpful.
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"I was put on this med due to degenerative arthritis in my neck and depression, (I was taken off the other mood meds and swapped to just this) For two weeks I took 30 mg, which didn't seem to help much, I also suffer from headaches/migraines. I was upped to 60mg which after the 3rd day was the first time in over 40 years I didn't wake up with a headache. It's been 4 days now with no headache, I have a bit of a humming in my ear, like when an amp is left on, but I'll take that over headaches any day, occasionally I've had the runs, but not sure if this is med related. I have noticed an improvement in my mood, also, I should mention also started seeing a Chiropractor for the first time and she's also done some miracle work on the neck."

In My Opinion (taken for less than 1 month) February 7, 2016

19 users found this comment helpful.
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