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Cymbalta for Depression User Reviews (Page 3)

Reviews for Cymbalta

Commonly mentioned side effects
  • JDh...
  • Taken for less than 1 month
  • September 25, 2016

"My outstanding physician and another member of the team recommended Cymbalta. I switched over from Zoloft and this medication works quite well. I suffer from Anxiety, Depression, PTSD, and severe nerve pains. The side effects have been quite minimal. I'm more involved in the community through volunteer activities, working, and accomplishing my goals. I'm more social and interactive. My depression and anxiety have decreased by at least 60 percent. My body pain has decreased. I'm more physically active, eating healthier and just more upbeat. A special thanks goes out to my physician, his team, and a fantastic representative who also recommended Cymbalta. Thank you for reading my review."

10 / 10
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  • Hut...
  • Taken for 2 to 5 years
  • January 30, 2017

"Good drug, not many side effects. It was the only one that worked for me, and I reckon I've tried every antidepressant on the market. Took 60mg for 2 years, didn't find it too hard to come off, was a bit grumpy for a couple of weeks, that's it. Also helped with my neck and nerve pain."

8 / 10
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  • R X...
  • Taken for 1 to 6 months
  • August 30, 2018

"Cymbalta is the only antidepressant that works for my depression & anxiety. With it, I feel calm and can think clearly and logically. I don’t catastrophize. I don’t get dark thoughts. Essentially no side effects. This drug radically changed my life for the better. A wonder drug."

10 / 10
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Frequently asked questions

  • one...
  • July 21, 2019

"I started Cymbalta for my depression as Zoloft wasn't able to keep up. I also have myofascial pain syndrome, fibromyalgia, bursitis, sciatica, SI joint dysfunction, osteoarthritis in my left knee and right hip. Cymbalta pulled me out of the horrible depressive spell, but it really calmed my fibro and myofascial pain. Like 85% better. Worse in the summer, so I'm experiencing it still helping me but a pain flare-up trying to fight through. I'm susceptible to migraines, Cymbalta has not given me headaches. When I first took it, it really knocked me out, made me feel gross, so I learned to only take it at night, and it really helps me sleep. Only two bad things that have happened are forgetting to take it, the next day, I'm pretty miserable and feel slightly out of it. The other is, stay sitting up after taking it to make sure it does not dissolve in my esophagus, or I get severe pain and diarrhea. I'm on 60mg since February, and I still feel good. I've never had anything help my chronic major depression like this has."

9 / 10
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  • myo...
  • April 29, 2018

"I started on 30 mg and am currently on 60 mg - first few days on it were awful, with bad insomnia, nausea/headache, fatigue. However, after ~5-6 days, most symptoms subsided (except the insomnia, which I use melatonin for). It's been about 2 months and I have to say this medication has been life-changing for me in terms of my mood/thoughts. I used to have such dark thoughts and a negative outlook on life, assuming the worst in people and hating everything about myself. That has completely changed and I can say for the first time in YEARS that I feel truly, completely, happy. This happiness is different because it persists even when not-so-great things happen in my life. I will say that the anxiety still lingers but honestly its effects on my depression make the anxiety super tolerable. I hope this medication works for others the way it worked for me - time will tell as far as how long this will last."

9 / 10
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  • Hap...
  • January 18, 2013

"I've been on Cymbalta 3.5 months for depression and I am very pleased to report that I feel even better now than I did the first 2.5 months. I had some gastro distress, dizziness, brain fogginess, and fatigue. All of my negative thoughts are gone, except near my menstrual cycle, I can laugh and cry again and am much better equipped to handle the stresses of life. I feel like I am finally back to normal. I'm posting for those of you just getting started on this medication. Give this medication some time, the side effects improve every month and it wasn't until I hit the three-month mark that I really felt better."

9 / 10
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  • Lau...
  • Taken for 1 to 6 months
  • October 13, 2024

"I am so happy to have found this medication. I took a genetic test that showed SSRIs were not as effective as an SNRI, so I switched to Cymbalta from Lexapro and Wellbutrin. I have had no side effects, and I feel better, anxiety and depression have subsided, and the arthritis pain I had is virtually gone. I couldn’t be happier! I take 60 mg per day."

10 / 10
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More FAQ

  • Cal...
  • Taken for 10 years or more
  • July 6, 2023

"I have been on Cymbalta for well over 10 years and have had excellent results. I am a retired physician, but when I practiced, I prescribed a lot of Cymbalta, and my patients loved it. It also helped my fibromyalgia patients. I still believe after all these years that it is still a great medication."

10 / 10
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  • Dan...
  • Taken for 1 to 6 months
  • October 16, 2015

"I've been taking Cymbalta for about 3 months now, and I can tell a drastic change in my overall mood, stress levels, pain levels, and energy. I started out on the 30mg, but requested an increase to 60mg after talking to my doctor. It was a great decision, and I'm finally beginning to feel the effects. I wake up smiling. Something I never thought I would do! And the good mood continues throughout the day. I also have chronic pain in my back, and I have noticed that the pain, which was a level 7 out of 10, is now about a 3. Amazing! That in itself is enough to keep me in a good mood. It was a bit difficult the first 2 months with the side effects and finding a good dose, but it is worth it in the end for sure."

10 / 10
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  • MEW...
  • Taken for less than 1 month
  • November 25, 2023

"Have been suffering from chronic lower back pain, torn cartilage in kneecaps, hip bursitis, and pain after 3 shoulder surgeries. Just kind of lost hope in feeling better. Lost interest in everything. Asked doctor for Wellbutrin, but because of the pain, he thought Cymbalta was a better fit. I was worried about gaining weight. Started 3 weeks ago on 20mg. I have no pain in my back, the swelling I've had for 5 years in my legs is gone, I’ve slept a full 8 hours every night. I notice a change in my attitude, mood, activity level. In just 3 weeks, I’ve lost 9 pounds, and feel like my old self. Life-changing!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 1, 2020

"I was diagnosed with PMDD and was prescribed Cymbalta. I don’t know if I’ve ever been so sick in my life: nauseous, vomiting, diarrhea, insomnia, loss of appetite, dry mouth, and all of this after one dose. Never again."

1 / 10
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  • Anonymous
  • October 28, 2014

"I was on this medication earlier this year and had to stop it because of cost and insurance. I have since been approved for medical assistance and my doctor has once again prescribed Cymbalta for my anxiety and depression. I had no side effects like I did with just about every other antidepressant under the sun. This has saved my life."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 18, 2016

"Over the years, I have tried a lot of different antidepressants. Some have been absolutely terrible for me and others have been alright, but Cymbalta has been life-changing. I was initially very worried about taking Cymbalta after all of the horror stories, but it has worked wonders for me. It really is an amazing drug!"

10 / 10
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  • JB8...
  • April 22, 2008

"Cymbalta I felt more like myself (Unlike Wellbutrin) and it made me focus more at school/work. The cons to the drug, (had to wait 3 days to fill my prescription) thus if you quit cold-turkey, you could have severe brain zaps (it feels like an electrical current running through your brain and it occurs a few times per hour when the withdrawals begin). Also, it didn't give me a burst of energy like Wellbutrin did, but Cymbalta made me feel more emotional towards others (rather than being numb to the world)."

8 / 10
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  • Som...
  • Taken for 6 months to 1 year
  • October 11, 2020

"I had been diagnosed with depression. I started with Cymbalta 30 mg for about 20 days and then switched to 60 mg for 6 months. This month I switched to 90 mg for more results. The change in my life was absolute. I feel a different man. I can do simple things (that I couldn't, like going shopping or having a haircut). My efficiency in my work is upgrading, etc. Thank you, Cymbalta. You saved my life. Negative effects: I have a little pain sometimes, and I have problems to ejaculate with my woman. Additionally, I eat more because I do more... 9.5/10 (9) for me."

9 / 10
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  • Kri...
  • Taken for 1 to 6 months
  • July 16, 2024

"I'm a 33-year-old female and was recently switched from Paxil to Cymbalta 60mg for depression/anxiety, Clonazepam 0.5 twice a day for panic disorder/PTSD, and Cyproheptadine 4mg for weight gain. This combination of medicines has been the best thing that ever happened to me. I was suffering for a long time. I no longer have racing/repetitive thoughts, no more panic attacks, sleep well, no depression. At first, I did have extremely dry mouth for about a week and a half. I had vivid dreams for about a month and a half that I couldn't tell if it was happening in real life or a dream, lol. I had excess sweating and hot flashes for about 2 weeks. All this has since stopped, and I feel great. I'm up to 118 lbs, look and feel amazing!"

10 / 10
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  • Fab...
  • February 16, 2019

"I am on day 3 and I am feeling better than I have in years. My Mom died in 2016 from breast cancer and my brother died in 2017 in a motorcycle wreck. My brother-in-law had a heart attack in 2018 (they bypassed him and he’s ok!) and his mom passed away from brain cancer this year. Also, a family friend just the other day. I have been convincing myself I could do this without help, but it became too much. (I have a teenage daughter) :) I decided I had to try something. I know it’s only 3 days, but if I feel this good now, I know it will get better! Thank you, Cymbalta!"

10 / 10
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  • Mar...
  • Taken for 1 to 2 years
  • May 22, 2020

"I tried SSRI (paroxetine) for a couple of years on and off. I was off the drugs for a couple of years, and then I decided to try the SNRI drug, first Effexor and then Cymbalta/Duloxetine. I took it for about 2 years. Taking this drug felt horrible. When I finally managed to get off of it (with extreme withdrawal symptoms), immediately after getting off the drug, I had leg pain and tingling in my feet and was diagnosed with Type 1 insulin-dependent diabetes. I was 30 at the time and have no history of diabetes in my very large extended family. I would love to hear from anybody with more to say about this… Something tells me my usage of SSRIs and mainly the SNRI is what brought about my T1D diagnosis. Anybody else with a similar story? What are your thoughts about this? Thanks."

1 / 10
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  • Dif...
  • Taken for less than 1 month
  • March 14, 2015

"My gosh... I can't say enough about this medication. I suffered through a series of traumatic events one three years ago, and felt that my dulled emotions were simply situational. Eventually, it got to the point where I couldn't maintain a clean house, missed deadlines, isolated myself from friends and others, and would pray that I wouldn't wake up some mornings. This is the first antidepressant I've tried, 30mg dose. Aside from slight appetite suppression, I've experienced no side effects. I've been on it almost a week, and I notice I awaken without that heavy depressive weight on my chest. The feelings of failure, the crying jags, and the crippling anxiety are diminishing already."

10 / 10
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101 Report
  • Anonymous
  • July 9, 2008

"I've taken Cymbalta for almost a year and it was great for depression. After finally getting to a place in my life that I did not believe I needed the antidepressants anymore, I decided to go cold turkey. This day marks the 7th day of not taking anything and I must say the detox is horrible. Talk to your doctor before going off this medication, as it has some terrible effects when coming off of it suddenly."

8 / 10
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155 Report
  • Tre...
  • Taken for 6 months to 1 year
  • September 30, 2019

"The most important thing I want to share here is that it is the most addictive substance I have ever taken (and I have tried at least 100 different drugs). It's not addictive because of the benefits it gives. It's addictive as anything because when you forget to take a pill, all hell breaks loose. I highly do not recommend this to anyone. If you consider taking it, DO NOT! UNDER ANY CIRCUMSTANCES. Better to be sick from your illness than to get another illness because of this medicine. Do some online research about Cymbalta, it hurts worse."

1 / 10
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  • tlw...
  • Taken for less than 1 month
  • September 16, 2013

"I love Cymbalta! I take it with 150mg of Wellbutrin XL. I am on 30mg at this time and in another week my Dr. wants me to up it to 60mg. I finally feel happy and have lots of energy. Combined with the Wellbutrin I have not gained any weight. Life is finally good again."

10 / 10
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  • Mat...
  • Taken for 2 to 5 years
  • September 16, 2019

"This drug has changed my life and probably saved it. I take only one 30 mg a day, but it does the job. I suffered from anxiety to the extreme, days on end without sleep. Anxious days are gone, thanks, Cymbalta."

10 / 10
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  • K55...
  • Taken for 1 to 6 months
  • February 4, 2020

"I have anxious depression, and I have been taking this drug for about one month. I started at 30 mg for a week and then switched to 60 mg until now. The first few days were horrible, I was sleeping about 12 hours per day and had a feeling of nausea, but finally, after a few days, everything was fine. Anxiety is totally gone, and I don't feel exhausted from my mood. I feel more powerful, and my mood is much better, but in any case, I am not happy. I also sleep very well. I will stick to this medicine. I recommend following doctors' prescriptions."

9 / 10
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60 Report
  • Anonymous
  • November 3, 2008

"Been taking 30mg since September 12th. Just had to go up to 60mg on October 28th. I love this medication. I have been on antidepressants for over 10 years, and this is the absolute best. I no longer occupy my time by thinking about how much life sucks but by figuring out the things I want to do that I haven't."

10 / 10
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141 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.