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Trulicity User Reviews & Ratings (Page 3)

Trulicity has an average rating of 5.3 out of 10 from a total of 970 reviews on Drugs.com. 38% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Trulicity

Commonly mentioned side effects
  • Jus...
  • Taken for less than 1 month
  • May 21, 2023

For Type 2 Diabetes "I started taking this medication last week, exactly a week ago today. It has been a horrible experience. The very next morning, I felt extremely nauseous and couldn't eat or drink anything throughout the day. I became so nauseous that I ended up getting dehydrated and started vomiting. I was sick all week long and almost went to the hospital every day. To be honest, I have had my fair share of long hospital visits and was hesitant to go to the emergency room. However, looking back, I should have been there multiple times this week. I'm not exaggerating. The fact that I am starting to recover from this sickness feels like a miracle. I became malnourished because I couldn't keep anything down, and now my body is struggling to absorb nutrients properly. As a result, I am experiencing shakiness, nausea, tiredness, irritability, and an overall horrible feeling that I can't seem to shake off. If you can, please pray for me. Thank you, and may God bless you. I urge you to exercise caution if you decide to use this medication and don't wait for the symptoms to accumulate. If something doesn't feel right, trust your instincts."

1 / 10
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  • Sri...
  • Taken for 6 months to 1 year
  • January 21, 2019

For Type 2 Diabetes "2nd Review: (I did my first review on 2018-10-25). I started Trulicity 5/2018, and for the first 5 months, I thought the gastro side effects may well kill me. I was very close to discontinuing. BUT... My A1C went from 10.6 (yikes!) to 6.4, and as of 1/2019, it is at 5.7 - hard to argue those results. This drug has commanded me to eat differently or face the consequences. In fact, the truth is, I don't eat a lot anymore at all. When I do, it's smaller portions, little grain products, light fiber because I feel full all the time. I've lost 15 pounds. Having made it through 5 months of OMG bathroom NOW issues... The view from the other side is pretty great."

10 / 10
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  • Hap...
  • Taken for 2 to 5 years
  • July 24, 2023

For Type 2 Diabetes "I have been using this medication for over two years and I must say I’m very happy with it. The only side effect I get every now and then is a little nausea, if I eat something with too much grease, it doesn’t have to be fried. Even if it’s baked with lots of cheese, and cheese makes the food greasy, I will get nauseated. The injection site still hurts, other than that, I am happy with it. Because I have some serious issues in my discs that cause me severe pain, I can’t do intense exercises except walking a little at a slow pace. Over the past two years, with the help of this medication and the little walks I take on a daily basis, I have lost well over 150 pounds, and my A1C is down to 5.6. This was a lifesaver for me. I am sad to see so many bad reviews on here regarding this medication. No medication is a miracle ready to happen overnight, and nothing is without side effects, even Tylenol may give side effects to some people. Give it time to work and add other activities into your daily routine."

9 / 10
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Frequently asked questions

  • daw...
  • Taken for 1 to 6 months
  • June 18, 2020

For Type 2 Diabetes "I tried Trulicity for 4 months, the stomach upset and sulfur burps were the worst, not to mention the stomach pain, nausea, and increased my acid reflux. Had to take two Protonix and Prilosec a day and still had heartburn from this injection. It's been 3 weeks since I stopped Trulicity. I am doing much better but still have the burps that I never had before this injection. Depending on what I eat, they turn into sulfur burps. Dropped my A1C from 8.8 to 8.4, lost 8 lbs. But not worth the stomach issues."

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 28, 2020

For Type 2 Diabetes "I took one shot of Trulicity 2 weeks ago. I missed a whole week of work because of nausea, dizziness, fatigue, and vision problems. I can’t think straight. I called my doctor and told her I was not taking this again. It’s been 2 weeks and I still feel horrible! Dizziness and nausea are terrible. Achy all over. How long does this stay in our bodies?"

1 / 10
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  • Bre...
  • Taken for less than 1 month
  • January 17, 2021

For Cardiovascular Risk Reduction "My doctor injected me with a Trulicity pen on Friday in her office. As time has gone on, now Sunday, I'm so sick. I have severe abdominal pain, an extremely sick feeling, threw up once, have diarrhea, terrible sulfur burps, and gas. No appetite, which I suppose is a good thing to a point, but I'm scared to eat due to the nauseating feeling. Overall, I just don't feel good. I cannot wait for it to wear off. I will never take this medication again, these side effects are not worth it."

1 / 10
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40 Report
  • Ste...
  • Taken for 1 to 6 months
  • May 17, 2021

For Type 2 Diabetes "I've been on Trulicity since January of this year, having one dose once a week. It still makes me feel nauseous. My side effects are I can't eat, bloating, diarrhea, painful pain in the lower abdomen. I've mentioned all this to my doctor, and she keeps saying my body just needs to get used to it. Don't think it will ever get used to this."

9 / 10
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37 Report

More FAQ

  • bes...
  • November 3, 2015

For Type 2 Diabetes "I started Trulicity about a year ago because the medication I was on kept crystallizing and was hard to inject. I have lost weight, about 22 pounds, over the course of a year. The biggest things to get used to were the nausea and the diarrhea, but after giving 4 weeks to adjust to the medication, my blood sugar does not spike like it used to, and I felt better. I don't have my usual cravings for anything bad for me, but I do have an appetite. I tell anyone who needs to lose a few pounds and lower blood sugar to stick with it. It will get better. I can't complain about the medication. All anti-diabetic agents cause stomach issues. Hang in there."

10 / 10
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68 Report
  • Zoe...
  • Taken for less than 1 month
  • November 2, 2020

For Cardiovascular Risk Reduction "I was prescribed this for weight loss, and it has been the worst thing ever. Bedridden and unable to work for 6 days now. Vomiting and diarrhea the whole day. Complete loss of control of my bowels. Unable to care for my kids. BP dropped to 74/48 at one stage, been to ED yesterday for IV fluids, but today it's worse than ever! Severe gastric upset, gas, pain, weakness, fatigue. Constant nausea that Maxolon and Ondansetron doesn't touch! I feel so awful! Don't risk this! I have heard of many now who have had these severe symptoms. I have not been this sick in 15 years! Diarrhea every 15-30 mins, using nappy rash cream on my bum now. Nightmare!"

1 / 10
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44 Report
  • Dee...
  • Taken for 6 months to 1 year
  • September 30, 2023

For Type 2 Diabetes "TRULICITY lowered my A1C from 11 to 6.5 in only a few months. At first use, I had mild symptoms like nausea and gas for maybe only the first 2 weeks. Other than that, I only had one bout of constipation that took 4 days to resolve. The constipation made me feel sick and I did have to limit food and was in bed for 2 days, but I figured out why it happened after tolerating the med for several months. I got comfortable with my diet and ate the wrong foods and overate. I ate greasy, sugary, and large portions in the week of the bad constipation. I immediately went back to smaller meals, no sugar, low carbs, and no greasy foods, and I was back on track. This was on the 1.5 MG dose I had been on for a while. People need to know that the harsh symptoms are coming from not regulating their diet and eating/drinking habits. That's why so many people get nausea, vomiting, and so on. You can't eat whatever you please on TRULICITY and expect it to not give adverse symptoms. Big no-no! Don't fool yourself."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • April 5, 2019

For Type 2 Diabetes "Trulicity almost killed me with gassy diarrhea. I was on it for about 4 months. It is a very violent drug. I've been off of it for 3 weeks and still have bad symptoms. Lost around 25 lb from pooping liquid, and I thought I was going to blow up from the gas. While going through this, I have heard of similar symptoms from other friends."

1 / 10
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  • Anonymous
  • February 20, 2020

For Type 2 Diabetes "Injected myself for the first time on a Friday night. Feeling very pleased as my levels dropped to 7s. Sunday arvo out and about with hubby. Started getting bad stomach pains. Just before getting into the car, I started projectile vomiting. It wouldn’t stop. Very embarrassed as this was on the footpath and road, and people could see. Pain still very intense in my abdomen. Got home and still projectile vomiting. Doctor prescribed me medicine to stop the vomiting. That worked, but the pain in my abdomen just intensified more. Had foul sulfur burping as well. Later that night was fully constipated, but did finally manage to go. Thought yay finally no more pain. Wrong! 5 minutes later explosive diarrhea nonstop. I’m still in intense pain, still got diarrhea, haven’t been to work all week. Never ever have I felt such intense pain. Doctors daily and still no relief. WORST medication ever! Stay well away from this torture drug!"

1 / 10
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  • kat...
  • Taken for less than 1 month
  • May 9, 2019

For Type 2 Diabetes "Nope! Trulicity is not for me! Vomiting every day multiple times, nausea, fatigue. I can't even lift my arm to brush my teeth or walk 10 feet without feeling like I'm going to pass out. Heart beating out of my chest. Only had one dose, never again. Poison!!!"

1 / 10
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  • Gen...
  • Taken for 1 to 2 years
  • November 22, 2019

For Type 2 Diabetes "Been on Trulicity for a year now and have lost 35 lbs. A1C is right where it needs to be. I used to take Metformin, and it was a nightmare with having to deal with diarrhea, extreme stomach nausea, and just anytime that I was out and about with errands or out to eat and having to worry or stress if I was going to have to rush getting to a restroom. Trulicity does have its side effects of fatigue here and there. It also suppresses appetite, which is a good thing. Stools are much better other than a spell of diarrhea once in a while, but nothing compared to Metformin. Trulicity is also easier to deal with-just one shot once a week compared to Metformin, where I was pilled to death at 500 mg, 2 in the morning and 2 in the evening, Monday through Sunday, 365 days a year."

8 / 10
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  • Poc...
  • Taken for 1 to 6 months
  • December 21, 2019

For Type 2 Diabetes "Diabetes for 8 years, taking 2000 mg Metformin. Dr. added 0.75 mg Trulicity per week. No real change in BSL (blood sugar levels) - still staying in the 180-225 range in fasting levels in the morning. Not really exercising. No big side effects either. On the day she changed me to 1.25 mg pen, I got a refill on my 0.75 mg pens plus the 1.25 mg pens a day or 2 later. So using the 0.75 mg pens 2x week - this has made the weight drop off and the appetite go down. I've lost 22 lbs in 3 months, which is a good rate and so encouraging to stay at it. No real bad side effects that would make me want to get off Trulicity. Diarrhea seems to come with eating fats. Maybe the 2x week is better for me. I'm only paying about $30 per 4 pen box on my insurance, so it is affordable. Just wonder if I ever had to stop using Trulicity - would the weight and appetite come back."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • March 15, 2019

For Type 2 Diabetes "I have been using Trulicity for about two months now, and it works. My blood sugar used to be between 140 to 160 after work daily. Since I started using Trulicity, it has been between 85 to 95 daily. I have had no side effects and have even lost some weight using this. I have nothing but good things to say about Trulicity."

10 / 10
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48 Report
  • Nik...
  • Taken for 6 months to 1 year
  • October 14, 2019

For Type 2 Diabetes "I started on the lower dosage and had absolutely no side effects. I stayed on that dosage for 8 weeks and started on the higher dosage. Now this new dosage has given me all the side effects. I will say they aren’t horribly bad. I can survive the side effects because my A1C has gone from 9.5 to 6.3."

10 / 10
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43 Report
  • Dot...
  • Taken for less than 1 month
  • September 13, 2019

For Type 2 Diabetes "My doctor attended a seminar and came back and changed my Humalog and put me on Trulicity. I recently had a triple bypass (heart surgery) and was very concerned about this action. I did research on this medication and found it was only tested on animals, not humans. It caused throat tumors in the animals and pancreatitis cancer. I then decided to see if anyone posted any reviews, and there are over 600 hundred. Thank you all for your reviews. You helped me and prevented me from serious complications. I did not take the medicine and called my doctor and informed them of this. You should make your own decision on what to put in your body. Doctors are about money and experiments, and they receive incentives."

1 / 10
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  • Pre...
  • Taken for 1 to 6 months
  • December 28, 2018

For Type 2 Diabetes "The first dose I did okay with, but each dose after it seems to make me sicker. I usually start feeling bad within 24 hours of taking the shot. It started out as just a stomach ache. Last month, I got so sick. I thought I had food poisoning or the flu. It started with burping up a rotten egg taste. My body felt like I was on fire. I was so weak all I could do was lay my head on the trash can and wait to vomit. Then the diarrhea and stomach cramps came. I spent 4 days throwing up and running to the bathroom. I took my shot yesterday and today, the same exact thing happened. I'm so sick. Burping started around 2 pm, by 5 pm, I knew I was going to vomit. By 6 pm, I was vomiting, and I continue to throw up, and the diarrhea has now come as well. I haven't gotten violently ill every time I take the shot, but after two times, I won't be taking it again. I've never felt so sick in my life. My numbers didn't go down enough to make me want to continue on this medicine."

1 / 10
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  • Kik...
  • Taken for 1 to 6 months
  • January 4, 2020

For Type 2 Diabetes "For the love of anything, don't take this if you can avoid it. I've taken Trulicity for 3.5 months now, hoping my body will somehow tolerate it. Not the case. I've lost over 40 lbs. I feel like I have food poisoning every day. Bloated. Diarrhea, constipation, horrid nausea. Now I am starting to vomit. Losing weight is good, but not like this."

1 / 10
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42 Report
  • Dap...
  • Taken for 1 to 6 months
  • September 12, 2019

For Type 2 Diabetes "It's been almost 4 weeks now since I've been on the Trulicity 0.75 mg weekly. I did experience some mild nausea and a few headaches, but overall, my experience has been great. My appetite has decreased a lot. I was advised to stay on the 1000 mg of metformin at bedtime by my endocrinologist, which balanced out the constipation and diarrhea. I am, however, gassy... lol... but I can deal with that. I have experienced some weight loss, but I don't know how much. I see it in my clothing, and I feel much lighter. I also have increased energy."

10 / 10
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43 Report
  • Ell...
  • Taken for less than 1 month
  • April 3, 2020

For Type 2 Diabetes "This is the worst medicine ever, and I’ve taken quite a few. I had to take Trulicity because my insurance won’t cover Victoza without a fight, and this is the second time I’m given low-rated/poorly tolerated medication for this reason. Thanks, Tricare. That same night, I had awful stomach cramping and diarrhea. Then the stomach pain was a little less severe but more persistent. I also suffered fatigue, constipation, bloating, sulfur burps, heartburn, nausea, dizziness, poor sleep, nightmares in addition to the stomach pain. Once it was so bad, it woke me up! I had constipation switched with diarrhea and heartburn for almost 2 weeks, and I stopped the medicine already. It stays in your system for DAYS and still messes with you. It’s awful."

1 / 10
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41 Report
  • Kee...
  • Taken for 1 to 6 months
  • December 1, 2019

For Type 2 Diabetes "I took this medication for 5 weeks. While informing my doctor of the awful side effects that I was having, he kept assuring me that I would soon feel better. After going to the emergency room on 3 different occasions for severe nausea and stomach pain that had me bedridden for almost 2 weeks straight, come to find out that this medication has given me pancreatic cancer. Do not, I repeat, do not take this medication!"

1 / 10
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58 Report
  • Nan...
  • November 12, 2019

For Type 2 Diabetes "I've been a diabetic for 23 years, and for the last 4 years, I've been all over the charts with my A1C. Dr. prescribed Trulicity last week, I should have read the reviews on this site first. I've been sick the last 4 days! I swear I felt it in my lungs the minute it was injected, then the nausea started. I've been in bed the better part of the last 4 days, but between the cramping, dizziness, diarrhea, headaches, and high blood pressure readings, I've decided it's not working for me. It's not worth the misery. I wanted to give it a chance, but I can't live like this any longer. Any food I put in my stomach feels like a sharp pain, it feels like my insides are turned inside out! I'm 58, and I've quit! Life's too short."

5 / 10
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  • Nev...
  • Taken for 2 to 5 years
  • July 2, 2016

For Type 2 Diabetes "I started Trulicity 0.75 mg in December of 2015 along with 1500 mg of metformin. My A1C was 9.3 at that time. My weight was 170 lbs. It is now July 2016, my A1C is 6.2 and my weight is 145 lbs. I lost a lot of weight, simply because I don't eat much now. Trulicity definitely helped with A1C and weight loss, but it totally destroyed my appetite. For this reason, I feel tired, fatigued, dizzy, and lightheaded. My doctor reduced my metformin to 500 mg a day extended release. I was taking the regular metformin before, will see how I do with 1 a day 500 mg extended release... Diabetes totally sucks! Ughhh. I hope they find a cure for it soon. Best wishes and good luck everyone! I will update you on how I do with this new change."

8 / 10
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