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Trulicity and Headaches: What Users Say (Page 3)

Reviews for Trulicity

Commonly mentioned side effects
  • der...
  • Taken for 1 to 6 months
  • June 13, 2017

For Type 2 Diabetes "Addendum to May 31st post: I'm still taking Trulicity .75 mg/.5 mL dosage, approaching week 5. My blood sugars continue to improve; fasting blood sugars 110-130; 2-hour post-meal blood sugars"

9 / 10
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  • tex...
  • Taken for less than 1 month
  • September 15, 2018

For Type 2 Diabetes "My A1C as of yesterday was an 11.5. Doctor prescribed a dosage of 1000 mg of metformin twice a day, and he started me on Trulicity 1.5. First shot was yesterday at about eight in the evening. My glucose readings have been under 125 (three times) since then. Not even 24 hours have passed. This is before eating. However, after about 18 hours after Trulicity, I have severe nausea and a headache. The kind that makes you shiver. Hoping it'll ease. Yes, hunger is diminished. I'm happy with the lower readings."

8 / 10
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  • Cha...
  • September 19, 2015

For Type 2 Diabetes "I was told that this would cause gastroparesis, and it has. 7th week on it, and it is so bad that I can't sleep. Bloated abdomen and sharp cramping pain in upper abdomen. No appreciable impact on daily blood sugar. No weight loss, rather a gain. Muscle tightness in neck and head, leading to headaches. I was doing okay with daily Victoza, but insurance wouldn't cover it and made me switch."

2 / 10
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14 Report

Frequently asked questions

  • mrs...
  • Taken for 1 to 6 months
  • April 13, 2017

For Type 2 Diabetes "Have been on Trulicity for the last 8 weeks, and apart from the odd light stomach cramp and less frequent but a little more severe headache, I haven't had any of the side effects that other people have mentioned. I have noticed a decrease in appetite, and as such, my portions have reduced, although I am now eating regularly where I wasn't before. My sugar levels at some stage were around the 14-15 range (130+), but since taking this, my morning levels before breakfast are between 9 and 11 (75-97), and my before evening meal levels are between 5.3 and 8 (34-64), depending upon what I have eaten during the day. In the last week, I have started a low carb, higher fat diet, which is where the lower readings have come from. On 0.75 at present."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 17, 2019

For Type 2 Diabetes "Took my first dose last week; I was prepared for nausea after the shot, but not for days of nausea. I was nauseated and could not stand for more than 10 minutes without having to lay back down. I started taking it on a Friday afternoon, thank goodness, because I would not have been able to go to work. I had a headache too (and I rarely have headaches). I was out of commission Saturday and Sunday; it was all I could do to go to work on Monday. Tuesday I started feeling better but had stomach pains. I did have a decreased appetite, but who doesn't when you're so nauseous? And I've lost two pounds, but I can't eat when I'm sick at my stomach. So, now it's time to take a second dose, and after reading all the comments, I don't think I want to lose another weekend."

5 / 10
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  • bpl...
  • Taken for 1 to 6 months
  • September 28, 2017

For Type 2 Diabetes "Second day after taking Trulicity, my ear turned bright red on the top, was hot to the touch, and was burning. Also, had a little headache. Called the doctor and was told to try another dose. The next week, got the red ear and burning sensation almost immediately, felt bad. At the third week and fourth weeks, had the red ears and burning down the sides of my throat. Fifth week had such a burning down the sides of the neck and throat, just could not move. Left work and covered up my head and slept. Couldn't eat. Did not take another dose. Did not have the nausea or other things I have seen listed, did have loss of appetite, didn't even want to drink anything. Has anyone else had the burning red ear tops or neck and throat?"

1 / 10
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  • bee...
  • Taken for less than 1 month
  • April 26, 2018

For Type 2 Diabetes "I am borderline diabetic. I didn't know that Trulicity needed to be refrigerated, which the manufacturer should print in bold letters on the box. Anyhow, after calling the pharmacist, he told me it was okay to take. I didn't feel any side effects until the second day. I woke up in the middle of the night and could not go back to sleep, and then the rest of the day felt lethargic. The next few days, I felt queasy and had no appetite. It seems like the symptoms come in the morning. I experienced gas pain that felt like I'd been kicked in my stomach. Today is day five, and I feel like I have the flu with mild fever (body aches, headache, etc.). I am still queasy, and I don't want to eat except saltine crackers. I am disappointed because I spent money on this, and I have three more injections, which I am not going to take. I can understand maybe a day or even two for side effects, but not all week. How is one supposed to function and go to work?"

2 / 10
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More FAQ

  • JLI...
  • Taken for less than 1 month
  • June 15, 2021

For Type 2 Diabetes "Nothing but positive results so far. Three injections over three weeks (once per week on Mondays) along with twice daily metformin 2000 mg per day and my sugar has gone from 421 to 106. Only complaint or side effect is the day of injection I do get a mild headache, but other than that, I feel fantastic."

9 / 10
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  • She...
  • Taken for less than 1 month
  • August 10, 2019

For Type 2 Diabetes "I take four Metformin and Trulicity, and every two weeks or so my stomach cramps like I have a virus, and then I throw up. TMI, but this looks like clear saliva mucus that comes up. Then sweat, and I have headaches throughout the night. I backed off Metformin to two to see how it goes."

3 / 10
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  • Suz...
  • Taken for less than 1 month
  • December 28, 2022

For Type 2 Diabetes "This drug feels like you are taking chemo. Was that the point? I wake up at 1600 and go to bed at 1900? After not eating for two days? I can't eat for waves of nausea and vomiting. I have a headache, tightness in my abdomen, shaking and fainting! Medical industry practicing again with toxic substances. And the worst part is, my numbers were already on the decline without side effects! The only explanation I can come up with is insurance companies don't make money now that insulin is going to now be $30.00 a month! Not $800.00, and this monstrosity is $1,000! Wrong direction for one out of ten 'cured' of diabetes."

1 / 10
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  • Mar...
  • Taken for less than 1 month
  • July 4, 2021

For Cardiovascular Risk Reduction "My doctor suggested I go on Trulicity as I had to lose weight and prevent my insulin resistance from becoming diabetes type 2. I am also taking Metformin 750 x 2 a day. This is my first week. Yes, I had headache, nausea. I also realized I have acid reflux if I eat processed foods or fried foods. That leads me to eat healthier and much less, thus I'm losing weight. I feel better this morning, and I mean better from the symptoms but also better than how I usually feel in the morning; more energetic, more focused! But I am super terrified from the reviews I am reading here, which are mostly negative. And I don't want to cause any serious issues to myself just trying to prevent diabetes. Anyway, good luck to everyone here and great health!"

5 / 10
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  • She...
  • Taken for 1 to 6 months
  • April 28, 2018

For Type 2 Diabetes "My fasting blood sugar was 199 on metformin, so I started Trulicity 5 weeks ago, and my sugars have come down some but are still 166 fasting. Is it worth all the side effects that I am now experiencing? I am not sure. The gas pains in my stomach are horrible, and I developed headaches and went to the doctor, and my blood pressure has skyrocketed to 200/110. I am now on a third blood pressure medication. My legs are aching, and I have heartburn every day. Have not lost any weight."

3 / 10
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  • TCa...
  • Taken for 1 to 6 months
  • September 20, 2017

For Type 2 Diabetes "Was on 0.75 for a month as supposed to boost this up to 1.5 - 0.75 was not too bad, weight loss, bit of headache now and then. When I started 1.5 everything went wrong. I would have a rock-hard lump for 3 or 4 days where I put the needle in. A side effect was a feeling like 'hives', constantly scratching my belly raw around the point of impact. Some vomiting, speech was off - more harsh, I work nights and lights were bothering me, also contributing to headaches. Been off it 2 weeks now and numbers have gone from 8-9 back to 13's, but all the side effects are gone and I feel better. That is what counts to me."

1 / 10
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  • TCa...
  • Taken for 1 to 6 months
  • September 20, 2017

For Type 2 Diabetes "Was on 0.75 for a month as supposed to boost this up to 1.5 - 0.75 was not too bad, weight loss, bit of headache now and then. When I started 1.5 everything went wrong. I would have a rock-hard lump for 3 or 4 days where I put the needle in. A side effect was a feeling like 'hives', constantly scratching my belly raw around the point of impact. Some vomiting, speech was off - more harsh, I work nights and lights were bothering me, also contributing to headaches. Been off it 2 weeks now and numbers have gone from 8-9 back to 13's, but all the side effects are gone and I feel better. That is what counts to me."

1 / 10
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  • Jay...
  • December 8, 2017

For Type 2 Diabetes "This is week 3 of me taking Trulicity, it started off okay, finally seeing blood sugar under 200. Loss of appetite, lost a few lbs, BUT then came the headaches, orange urine, bad stomach cramps, and now my foot has been swollen for a week. I went to the ER, they said I was fine. Could be side effects of the Trulicity and told me to check with my doctor. I was on Januvia, glipizide and never had these kinds of side effects. Metformin makes me so sick. I'm going to my doctor today to prescribe something else, as I can't deal with the Trulicity."

3 / 10
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  • BAM...
  • Taken for less than 1 month
  • September 6, 2021

For Type 2 Diabetes "I took 1 injection of Trulicity, 0.75 mg on August 18, 2021. Several hours later, I had a terrible headache, the back of my neck hurt, my shoulders and arms hurt too, nausea, and no appetite whatsoever. Fourteen days later, my heart rate went up, four days later, it went up again. I read that increased heart rate is a side effect of Trulicity, so I wonder how long it takes to completely clear my system? I took my one injection 18 days ago, and I read that Trulicity has a half-life of 5 days, so how many days will it take to get out of my system?"

3 / 10
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  • Oma...
  • Taken for less than 1 month
  • July 6, 2021

For Type 2 Diabetes "I took my first injection of Trulicity one week ago. I will never take it again. I've had severe stomach pain, diarrhea, painful acid reflux; keeping me up all night, headache, lethargy, depression, and now...a rash has shown up on both legs. This truly has been a nightmare week. And, to think that it will take a month to leave my system!"

1 / 10
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  • Joh...
  • Taken for 1 to 6 months
  • July 6, 2021

For Type 2 Diabetes "Marginal works at reducing my BGL and too many side effects to consider staying on Trulicity. I have had headaches, constipation, fatigue, and an overall feeling of sickness since I started on 1.5 Trulicity a month ago. After 4 treatments, I am done with trying this as a means to help my type 2 diabetes. Personally, I just concluded that Trulicity made me feel worse than any positive effect it had on my diabetes."

2 / 10
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  • Ger...
  • December 14, 2017

For Type 2 Diabetes "Awful heartburn, belching, headaches, nausea, and absolutely no appetite, lost over 7 lbs in 4 weeks, could not afford to lose weight. Worst medication I have ever been on. The only good thing about it was it did bring down my blood sugar levels."

3 / 10
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  • Van...
  • Taken for 1 to 6 months
  • July 12, 2021

For Type 2 Diabetes "Well, I've been luckier than some. No vomiting and only diarrhea when I ate too much cheese. I've been on it for 4 weeks, and the first week was terrible - waves of nausea and bad headaches. The nausea has gotten better, but the headaches continue, and I have pain consistently in my upper jaw on both sides (nerve issue?). I am really trying my best to tolerate this drug because it has dropped my glucose levels by half, and I've lost 11 lbs. We will see - the headaches and jaw pain are pretty bad. I can live with the nausea."

8 / 10
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  • Kel...
  • July 6, 2021

For Type 2 Diabetes "So I will be going on my 4th week of using Trulicity. I have had quite the experience. For the 1st 2 weeks I thought I might not be able to go through with it due to side effects of diarrhea, nausea, headache, feeling of being carsick, no appetite. Then finally it subsided. I have been taking a new high blood pressure med and metformin 750 mg 2 times a day. All started the same day so I thought maybe the combination of new pills all at once had done me in. Well, I missed a day of metformin and blood pressure meds on accident as I am not used to taking pills every day. And omg!! Diarrhea and sick since. Like my body is getting used to it all over again. I am happy with the no appetite though."

9 / 10
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  • Kez...
  • Taken for less than 1 month
  • January 30, 2020

For Type 2 Diabetes "Newly diagnosed Type 2, put straight onto this drug, Trulicity. Bad side effects: nausea, headache, dizziness, no appetite, blurred vision. Getting off this, never to take it again."

1 / 10
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15 Report
  • KKV...
  • Taken for less than 1 month
  • January 11, 2019

For Type 2 Diabetes "I had to quit taking Trulicity. It gave me stomach pain, nausea, headaches, and mood swings. Trulicity also dragged my blood sugar down every afternoon below 60. Never again!"

1 / 10
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16 Report
  • Jlt...
  • Taken for less than 1 month
  • January 8, 2016

For Type 2 Diabetes "The drug from hell... For the first 3 days, severe nausea, mega headaches, vomiting.... I will not take another injection."

1 / 10
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23 Report
  • Tak...
  • Taken for less than 1 month
  • February 16, 2020

"This drug, Trulicity, is terrible. Do not take this drug. Stay away! Made me feel horrible. Vomiting, dizziness, no appetite, weak, headaches. I will never take this again."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.