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Diphenhydramine User Reviews & Ratings (Page 4)

Brand names: Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Diphen, Benadryl Children's Allergy, Sleep Tablets, Diphenhist, Calm-Aid, Nytol, Sominex, Unisom SleepGels, Dormin, Diphenyl, Buckley's Bedtime, DPH, Valu-Dryl, Altaryl, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, ConRx Allergy, Dicopanol, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphedryl, Diphen AF, Diphen Cough, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Diphenadryl, Genahist, Aller-G-Time, Sleep Tab II, Nytol QuickCaps, Trux-adryl, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Hydramine, Silphen Cough, Diphenylin, Hydramine Compound, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Allermax, Diphendryl, Twilite, Banaril, Aler-Tab Siladryl Allergy Sleep-ettes D Diphenydramine Quick Melt Diphenmax Ben-Tann Dytan Vanamine PD Pharbedryl Histaprin Z-Sleep Aurodryl Children's Allergy Unisom SleepMelts Simply Sleep Complete Allergy Relief Dytuss Miles Nervine Scot-Tussin Allergy Sleepwell 2-nite …show all brand names

Diphenhydramine has an average rating of 5.5 out of 10 from a total of 547 reviews on Drugs.com. 43% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Diphenhydramine

Commonly mentioned side effects
  • ric...
  • March 23, 2023

Diphenhydramine for Insomnia "I have used this product for two weeks now and have found absolutely no difference in my sleep pattern. I am still taking nearly an hour to get to sleep, then waking two or three times during the night."

1 / 10
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8 Report
  • Luc...
  • Taken for less than 1 month
  • February 6, 2020

Diphenhydramine for Insomnia "Have been taking Nytol for 2 weeks now since severe flu knocked my sleep pattern out, having no effect at all, it is absolute rubbish. Don't make me feel sleepy at all, if anything, the opposite - spend many hours awake staring at the clock! Have tried taking one early in the evening and one before bed as advised, still doesn't work... Oh, and they smell funny and taste even worse, they are going in the bin - waste of money."

1 / 10
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18 Report
  • Zzz...
  • Taken for less than 1 month
  • September 26, 2022

Diphenhydramine for Insomnia "Desperately in need of sleep and decided to take ZzzQuil tablets. This product DOES NOT WORK! I tossed and turned, horribly restless, could not get any sleep! Heart pounding, pulse at high speed! Vicks must remove this product, like now!"

1 / 10
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10 Report

Frequently asked questions

  • Sic...
  • Taken for 1 to 6 months
  • June 7, 2019

For Nausea/Vomiting "Have nausea often, especially if I undereat one day. I'll be nauseous and have trouble eating for days on end. I've been given Zofran, Phenergan, and Bentyl at the ER. When those ran out and the nausea didn't, I looked on the web and saw Benadryl recommended. It's worked very well for me every time! You will most likely be pretty sleepy, though. Plan on some nap time."

9 / 10
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16 Report
  • lab...
  • August 24, 2008

Diphenhydramine for Insomnia "After trying several different sleeping aids, I ran across Compoz in K-Mart. I hadn't seen it anywhere else, so I thought I would give it a try. I got a good night's sleep for the first time in quite a while. I still take it occasionally and still get that good night of sleep. You can't take it every night for an extended period of time, or it won't work as well. I can promise you that."

8 / 10
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34 Report

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  • JJF...
  • Taken for 1 to 2 years
  • October 20, 2020

Diphenhydramine for Insomnia "I consider ZzzQuil a low-level sleep aid, and that is all I need. It works great for me. I have no problem falling asleep. I often wake up and can't go back to sleep for 90 minutes. But if I take a 1/2 dose of ZzzQuil, I can fall right back to sleep. It does not leave me hungover. My wife and I both take it very often. Probably too often. I'm slightly worried that I am addicted to the non-addictive ZzzQuil LOL."

9 / 10
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13 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • October 17, 2020

Diphenhydramine for Insomnia "I have tried everything non-prescriptive for sleep, and Sominex really works. I am 6 ft and normal build and only need 1/4 tablet. I've worked out this is the optimal dose for me, so I can still function well in a busy job the following morning. Anything more than 1/4 tablet and I feel too groggy to function properly the next day."

9 / 10
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13 Report

More FAQ

  • Dow...
  • September 26, 2010

Diphenhydramine for Insomnia "I really like Unisom SleepGels. I work at night, so sometimes I have difficulty sleeping in the mornings. They help me get the sleep I need, with no grogginess. And I only take them when I'm too hyped up to go to sleep, but I need to sleep."

9 / 10
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32 Report
  • The...
  • Taken for 1 to 2 years
  • August 13, 2022

Diphenhydramine for Insomnia "I'm in constant pain as waiting to be called in for hip replacement, so just cannot sleep. Also, even though I'm tired, my brain just will not turn off. SOMINEX is a brilliant over-the-counter pill that lets me sleep ALL night. I take half to one pill when I go to bed, as I like to read before sleeping. I start feeling relaxed and ready to sleep after about an hour, and then before I realize it's morning. I wake up fine with no problems at all. I shall continue taking these - I'm 70 years of age - till I meet my maker."

10 / 10
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9 Report
  • dip...
  • May 3, 2010

Diphenhydramine for Insomnia "Works excellent if you haven't built a tolerance to it. After a few days of use, you may find the medicine is less effective than it was when you first used it. Benadryl knocks me out quite quickly when I use it, the only problem I have with it is that I tend to oversleep or wake up groggy the morning after, which is generally relieved with some sort of caffeinated beverage."

7 / 10
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33 Report
  • Big...
  • Taken for 6 months to 1 year
  • October 31, 2017

Diphenhydramine for Allergic Rhinitis "I have allergic rhinitis. Was prescribed Zyrtec, Allegra, and Flonase, and I couldn't get relief. A pharmacist suggested Benadryl, and it's the only med that works. Took a generic brand, and all hell broke loose. Went back to the original, and I'm feeling much better."

9 / 10
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21 Report
  • Jem...
  • Taken for less than 1 month
  • January 22, 2019

Diphenhydramine for Insomnia "I took half of one for a transatlantic flight - it worked well. I woke up at 5 a.m. to land, took a train from Newark to Manhattan, fell asleep for a further delicious three hours once I reached a bed. That would have been impossible without the Sominex. A whole one seems like madness!"

8 / 10
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17 Report
  • Anonymous
  • July 25, 2009

Diphenhydramine for Insomnia "I love Unisom SleepGels. I can't go to sleep and then can't stay asleep. This has fixed that with no grogginess next morning, no matter if you sleep 4 or 5 hours or 8 or 9 hours and feel the same. No hallucinations or anything. Best yet, it's over the counter and cheap."

10 / 10
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38 Report
  • DE1...
  • October 16, 2009

Diphenhydramine for Insomnia "After having scripts for lots of different benzodiazepines and sleeping pills, I still rely on this a couple times a month. The only problem is, after a couple of days, it loses its effectiveness. It is perfect for sleep and not feeling drugged."

9 / 10
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34 Report
  • Boo...
  • Taken for less than 1 month
  • July 23, 2020

Diphenhydramine for Insomnia "I tried this Sominex for sleeping, and it's absolutely useless, tbh. Save your money. I've seen people review they take half a tablet, and they sleep great. Don't know how. I take 2 tablets and have zero effect whatsoever."

1 / 10
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18 Report
  • Mor...
  • November 15, 2015

For Nausea/Vomiting "I tried everything yesterday to stop throwing up acid. I went from Nexium to Zantac to Pepto to Tums, nothing helped, and it all just came back up an hour later. Thankfully, my brother is a paramedic and told me about how they use Benadryl for their nausea patients, so I took 3 of the 25 mg tablets, and it worked!!"

10 / 10
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24 Report
  • las...
  • Taken for 6 months to 1 year
  • September 5, 2017

Diphenhydramine for Insomnia "I have used ZzzQuil off and on for a year or so to help me fall asleep. I have noticed that on the nights that I take it (1/2 dose), the next day I experience head shaking tremors that I have to consciously control, especially when I drive. I will no longer take this medication as I am concerned about the side effect."

4 / 10
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20 Report
  • San...
  • October 18, 2015

Diphenhydramine for Insomnia "I have had problems sleeping lately. Someone recommended me to use these pills, and they actually are really good. I have used them twice in a row and have slept well and even woke up when the alarm came on."

10 / 10
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24 Report
  • Cow...
  • Taken for less than 1 month
  • December 17, 2020

Diphenhydramine for Insomnia "Ugh, just no. The first time I tried this tablet, I took a whole one. Did what it said on the tin, and I was knocked out within the hour. I slept for thirteen hours and woke up feeling terrible. Groggy, dizzy, and as if my limbs were tied down with iron weights. I wanted to cry at the tiniest things and felt bloody awful. Having slept for so long, I couldn't sleep it off. The next night, I took half a pill. In the morning, I didn't have the same grogginess, but I wasn't firing on all cylinders. I was also gripped with horrible anxiety that stayed with me until about 9 pm. I didn't take anything last night, and I feel absolutely fine. I find it difficult to chalk this up to coincidence."

2 / 10
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15 Report
  • Rut...
  • Taken for less than 1 month
  • November 4, 2019

Diphenhydramine for Insomnia "I only took ZzzQuil for two nights. Both nights I slept just a few hours and woke up with a bad headache two mornings in a row that Advil didn't help, and it usually always does. I also noticed yesterday when watching a football game that my vision was acting weird, blurring like. I DO NOT recommend this to anyone. I have tried many over-the-counter meds, and nothing really works - does nothing at all for me, but this stuff made me miserable."

1 / 10
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15 Report
  • Pow...
  • February 15, 2016

Diphenhydramine for Allergic Reactions "I couldn't stop coughing for one week. I lost my voice and had severe lung pain due to the coughing. I went to see a pulmonologist and did X-rays, the results were negative. My lungs were clear and had no infection whatsoever. He recommended that I go to Walmart and buy Claritin pills, but I was desperate last night to have a good sleep without coughing all night. I haven't been able to sleep with this horrible, killing cough, not to mention dry nose, itchy ears, and itchy throat. Last night I took two regular Benadryl pills and slept like a baby for 10 hours straight. The only problem is that I make my living driving and can't take the pills during the day. Probably I will take Claritin during the day, but I honestly prefer Benadryl, way more effective."

10 / 10
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22 Report
  • Anonymous
  • October 7, 2008

Diphenhydramine for Allergic Reactions "I am severely allergic to all nuts, and I always keep a few pills with me. If I eat something that has been in contact with nuts, I take two pills or a gulp of the syrup, and my itchy mouth and throat, swollen lips are instantly soothed. The syrup does work faster than the pills, but pills are lighter to carry around. I once ate a huge piece of hazelnut chocolate, and having Benadryl on me really saved me. It won't work on severe reactions, i.e., eating peanut butter, but it is definitely a lifesaver for all other allergic reactions. I am never without Benadryl and my EpiPen. The only thing to look out for is intense drowsiness, so make sure to be at home to take a long nap when it takes effect."

10 / 10
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36 Report
  • Con...
  • April 26, 2017

Diphenhydramine for Allergic Reactions "I have no rest every time I take Benadryl. I feel I have a really bad reaction as I feel restless, my body feels itchy, nauseous, and it makes me feel angry. Feeling restless really hurts my stomach. Am I allergic to it, or is it a bad reaction?"

2 / 10
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22 Report
  • Mic...
  • Taken for 2 to 5 years
  • April 11, 2018

For Nausea/Vomiting "Better known as Benadryl. Every time anyone is puking, I can always rely on this to immediately stop it. (Chewable form) My children have struggled with nausea with no help from any medication until this was brought to my attention. This is the absolute only thing I will use for nausea/vomiting."

10 / 10
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17 Report
  • Tom...
  • Taken for less than 1 month
  • February 24, 2019

Diphenhydramine for Insomnia "They do help me sleep, but I feel really terrible in the morning. Very groggy and very short-tempered. Have had to throw the pack out, as I feel so awful in the mornings. I've not noticed this to this degree of morning grogginess with other sleeping tablets. Horrible stuff!"

3 / 10
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17 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.