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Diphenhydramine Sleep Aid Liquid

Generic Name: Diphenhydramine (Sleep Aid) Liquid (dye fen HYE dra meen)

Medically reviewed on Sep 5, 2018

Uses of Diphenhydramine Liquid:

See also: Xolair
  • It is used to treat sleep problems.

What do I need to tell my doctor BEFORE I take Diphenhydramine Liquid?

  • If you have an allergy to diphenhydramine (sleep aid) liquid or any part of diphenhydramine (sleep aid) liquid.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take diphenhydramine (sleep aid) liquid with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Diphenhydramine Liquid?

  • Tell all of your health care providers that you take diphenhydramine (sleep aid) liquid. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
  • Do not take diphenhydramine (sleep aid) liquid for longer than you were told by your doctor.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how diphenhydramine (sleep aid) liquid affects you.
  • Do not use with other products that have diphenhydramine.
  • Avoid drinking alcohol while taking diphenhydramine (sleep aid) liquid.
  • Talk with your doctor before you use other drugs and natural products that slow your actions.
  • If you are 60 or older, use diphenhydramine (sleep aid) liquid with care. You could have more side effects.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using diphenhydramine (sleep aid) liquid while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • Do not give to a child younger than 12 years of age.

How is this medicine (Diphenhydramine Liquid) best taken?

Use diphenhydramine (sleep aid) liquid as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food. Take with food if it causes an upset stomach.
  • Take diphenhydramine (sleep aid) liquid at bedtime.
  • Measure liquid doses carefully. Use the measuring device that comes with diphenhydramine (sleep aid) liquid. If there is none, ask the pharmacist for a device to measure diphenhydramine (sleep aid) liquid.
  • If you have phenylketonuria (PKU), talk with your doctor. Some products have phenylalanine.

What do I do if I miss a dose?

  • This medicine is taken on an as needed basis. Do not take more often than told by the doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Change in balance.

What are some other side effects of Diphenhydramine Liquid?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling sleepy.
  • Dizziness.
  • Thickening of mucus in nose or throat.
  • Feeling nervous and excitable.
  • Upset stomach or throwing up.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Diphenhydramine Liquid?

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.
  • Do not freeze.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about diphenhydramine (sleep aid) liquid, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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