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Premarin and Anxiety: What Users Say

Anxiety: mentioned by 3 users (3.6%)

Based on user experiences from 84 Premarin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 21.4%
hair loss 8.3%
night sweats 8.3%
headaches 6.0%
mood swings 6.0%
bloating 4.8%
dizziness 4.8%
pain 4.8%
anxiety 3.6%
depression 3.6%

Reviews for Premarin

  • blo...
  • Taken for 5 to 10 years
  • February 21, 2014

For Postmenopausal Symptoms "Complete Hysterectomy: I was on Premarin started about 6 weeks after hysterectomy because I couldn't handle the restless leg syndrome and having to move all the time. I was put on 0.625 mg, was on it from 2007 until 8 months ago. 5 weeks after doc took me off, my whole body and life went to double hockey sticks!! Anxiety, Severe! OCD crazy uncontrollable, and panic disorder through the roof. I am on Celexa 20mg daily and 1.75 mg broken into 6 doses. It works, but I don't understand why it just doesn't work the same. I never had such bad OCD, anxiety, or panic like this while on it and I want it back! I am gonna go get mammo, if it comes back clean, I'm going back on Premarin! Will my life go back to normal? Will I feel like me again, and want to enjoy life? I have two appointments."

10 / 10
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  • Got...
  • March 18, 2018

For Postmenopausal Symptoms "Experienced menopause at an early age, had extreme menstrual problems from the beginning starting at about age 8. I am told after going through much menstrual problems my whole life, I have several fibroids. Hoping that after menopause they would naturally shrink. Mine grew and cause me extreme pain. Hormone therapy has relieved this pain. However, side effects I think cause me anxiety, and I cry easily. When I try to cut back, I only take it twice a week, the pain comes back, which is severe. I cannot stop taking it, but the cost is almost $300 for the prescription, as I have no insurance for this. I noticed in the comments no one else mentions it used for this problem, does anyone know?"

8 / 10
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10 Report
  • tin...
  • Taken for less than 1 month
  • February 21, 2023

For Postmenopausal Symptoms "It's been two nights since I took the first dose of vaginal cream (1/2 gram) for vaginal pain. Since taking it, I have developed terrible anxiety, felt spacey all day, had a headache, and had trouble sleeping. My reflux, which was under control with Pepcid, has worsened. My doctor does not think these are side effects of the medication, but I do not believe that. Maybe the side effects will get better after more doses, but I am reluctant to continue using Premarin."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.