Premarin Alternatives Compared
| Premarin (conjugated estrogens) | Estradiol | Estradiol Patch (estradiol) |
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| Premarin (conjugated estrogens) | Estradiol | Estradiol Patch (estradiol) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Abnormal Uterine Bleeding, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Hypoestrogenism, Oophorectomy, Breast Cancer - Palliative, Prevention of Osteoporosis, Primary Ovarian Failure... View more |
Related suggestions Postmenopausal Symptoms
Atrophic Vaginitis
Prostate Cancer
Oophorectomy
Popular comparisons
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| More about Premarin (conjugated estrogens) | More about Estradiol | More about Estradiol Patch (estradiol) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
Estradiol has an average rating of 5.8 out of 10 from a total of 592 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Estradiol Patch has an average rating of 4.6 out of 10 from a total of 170 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 54% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Premarin side effects |
View all Estradiol side effects |
View all Estradiol Patch side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic approved | |||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Premarin prices |
View all Estradiol prices |
View all Estradiol Patch prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other conjugated estrogens brands include: Premarin Intravenous | Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
16 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 355 drugs are known to interact with Premarin:
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A total of 390 drugs are known to interact with Estradiol:
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A total of 390 drugs are known to interact with Estradiol Patch:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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May 08, 1942 |
July 23, 1975 |
N/A |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Estrace
Estrace (estradiol) is used to treat symptoms of menopause such as hot flashes and vaginal dryness ...
Estradiol Patch
Estradiol Patch is used for atrophic urethritis, atrophic vaginitis, breast cancer, palliative ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Vagifem
Vagifem vaginal inserts are used treat menopause symptoms such as dryness, burning, and irritation ...
Estrace Vaginal Cream
Estrace Vaginal Cream is used for atrophic urethritis, atrophic vaginitis
Prempro
Prempro (conjugated estrogens and medroxyprogesterone) is used to treat the symptoms of menopause ...
CombiPatch
CombiPatch is used for atrophic urethritis, atrophic vaginitis, hypoestrogenism, postmenopausal symptoms
Conjugated estrogens topical
Conjugated estrogens topical is used for atrophic urethritis, atrophic vaginitis, postmenopausal symptoms
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.