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Xcopri User Reviews & Ratings (Page 2)

Xcopri has an average rating of 8.1 out of 10 from a total of 44 reviews on Drugs.com. 73% of reviewers reported a positive experience, while 5% reported a negative experience.

Reviews for Xcopri

Commonly mentioned side effects
  • Som...
  • Taken for 1 to 2 years
  • July 1, 2024

For Seizures "Made my already bad memory worse, was extremely dizzy, and it started giving me horrible rage and anger issues. Talked with a doctor, lowered the dosage, took B6 to help with the other side effects. Got the dosage right and it worked wonders in stopping the seizure onset."

7 / 10
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  • Sim...
  • Taken for 1 to 6 months
  • February 19, 2025

"In my childhood, the seizures were just lightheadedness that lasted 5 to 10 seconds, but around my early to mid-20s, they got heavier. For at least 20 years, I must have tried at least 20 different AEDs and combinations of them, but they either only barely worked, didn't work, or made it worse until, a few years ago, I got a VNS implant, which started making a difference, and a few months ago, I was prescribed 3x100 mg Xcopri per day with some other AEDs, and I haven't had a seizure in about 6 months! The main side effect for me is drowsiness, so I take it at night with my other nighttime AEDs. When I started taking them, they were a bit difficult to swallow (narrow throat), but it got better over time. I just hope the Xcopri keeps working for me, unlike many other AEDs I've taken over the years that worked a few weeks or months, then stopped for some reason."

9 / 10
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2 Report
  • Ano...
  • Taken for 6 months to 1 year
  • June 7, 2025

For Seizures "Used in combination with lamotrigine. Been seizure-free for 7 months. Side effect: lack of energy and sleepiness (sleep 9-10 hrs a night plus a 30-60 min nap). NOTE: I cannot recommend this drug - only a doctor can."

6 / 10
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1 Report

Frequently asked questions

  • mdb...
  • Taken for less than 1 month
  • July 20, 2025

For Seizures "Let me start by saying: ask your doctor to be honest about side effects and then list the pros versus the cons. My experience has been terrible, side effects that include nausea, abdominal pain, constipation, headaches, double vision, and severe dizziness. Add the fact that certain migraine medicines (Qulipta, Nurtec) interact with Xcopri was the deal breaker, but I tried to push through the first 3 weeks and failed. I was unable to do so because the side effects weren't worth adjunctive therapy. New isn't always the best."

3 / 10
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  • Ano...
  • Taken for 6 months to 1 year
  • August 24, 2025

For Seizures "I have been taking Keppra for 6 years, 1000 mg twice a day, and Depakote 500 mg twice a day. Have had breakthrough seizures the entire time. My new neurologist (who specializes in epilepsy) weaned me off Depakote and added Xcopri 500 mg. Thankfully and blessed, I have been seizure-free for almost a year!"

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 17, 2023

For Seizures "Xcopri has given me many side effects, including fainting, fast heartbeat, weakness, and more. The side effects I've experienced are not worth it."

4 / 10
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19 Report
  • Xco...
  • Taken for 6 months to 1 year
  • February 11, 2024

For Seizures "Has been excellent in terms of seizure control but needing to reduce dose due to side effects - not being able to wake up & aggression."

7 / 10
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12 Report
  • Sco...
  • Taken for less than 1 month
  • August 15, 2024

For Seizures "Seizures are great, but lots of side effects: slurred speech, off balance when I walk, constipation, weight gain, and tiredness. And these are some that I can think of."

8 / 10
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6 Report
  • Anonymous
  • August 30, 2022

For Seizures "It works! It is 1,800 for a 30-day supply if you don't have the manufacturer coupon."

10 / 10
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15 Report
  • Ter...
  • Taken for 6 months to 1 year
  • May 30, 2025

For Seizures "It makes me sleepy at 7 pm. I wake up at 3:30 am eating."

6 / 10
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2 Report
  • Har...
  • Taken for 1 to 6 months
  • April 14, 2024

For Seizures "Xcopri has been good during all increases up to 200mg. By day 5 at 200mg, we experienced dizziness, loss of balance, verbal confusion, headaches, heart palpitations, and overall fatigue and weakness."

8 / 10
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  • Edd...
  • Taken for 1 to 6 months
  • July 14, 2024

For Seizures "Xcopri has been my favorite medicine for seizures since it blocks sodium ion channels and does good to GABA. The medicine has reduced my seizures to one per month."

9 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • January 2, 2024

For Seizures "Works, have the fewest seizures I've ever had, maybe one small one at night."

9 / 10
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7 Report
  • Cal...
  • Taken for 1 to 2 years
  • October 18, 2024

For Seizures "I still have seizures, but they aren't as bad, where I used to bite my tongue bad, I now stay more aware and can ride them out better."

9 / 10
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2 Report
  • Kit...
  • Taken for 6 months to 1 year
  • March 3, 2024

For Seizures "Very effective for focal seizures for about 9 months. The auras are creeping back over the past few months, and I had several breakthrough seizures during a recent bout of flu."

9 / 10
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  • Ano...
  • Taken for 2 to 5 years
  • April 17, 2025

For Seizures "Used along with Keppra, I take 250 mg daily, and it has cut down a lot of the amount of seizures I have to 1 occasionally. I use it to treat absence seizures."

10 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • March 14, 2023

"Vaginal bleeding. Think it's medications not interacting well and still trying to figure out which ones it can be since I am on multiple medications."

10 / 10
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  • sei...
  • Taken for 1 to 6 months
  • January 17, 2025

For Seizures "Fantastic! The only drug that has worked for me. It's my 5th drug. I'm taking it with Lacosamide. Side effects are dizzy and sleepy, but I'll take it."

10 / 10
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  • Tom...
  • Taken for 1 to 2 years
  • March 1, 2025

For Seizures "I was prescribed Xcopri along with Lamotrigine and Topiramate. It is working for me very much."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.