Xcopri and Drowsiness: What Users Say

• Crs...
• February 1, 2021

For Seizures "I've been on every medication for seizures, have had my right temporal lobe removed, have a VNS, was doing the medical marijuana and not one thing has helped my seizures. As soon as I started taking this drug Xcopri, my seizures have stopped. Was having them every day and haven't had one in almost 3 months now, I just can't even believe it!!! The only downfall is the side effects. I first would just want to sleep all day long, had no energy at all, I couldn't think straight or remember things. I would talk and move very slowly, run into things like I was drunk! The sleeping has gotten better, I can stay awake all day now. I still have problems with memory and can't make decisions to save my life!!! I'm still very slow at things and can't walk straight. I'm at 100 mg 1x a day. I just finished taking my amitriptyline for sleep, and now I'm only taking Onfi in the morning. Still on Briviact, Lyrica, Lexapro, Buspar...but so far, so good!!!!"

• Sim...
• Taken for 1 to 6 months
• February 19, 2025

"In my childhood, the seizures were just lightheadedness that lasted 5 to 10 seconds, but around my early to mid-20s, they got heavier. For at least 20 years, I must have tried at least 20 different AEDs and combinations of them, but they either only barely worked, didn't work, or made it worse until, a few years ago, I got a VNS implant, which started making a difference, and a few months ago, I was prescribed 3x100 mg Xcopri per day with some other AEDs, and I haven't had a seizure in about 6 months! The main side effect for me is drowsiness, so I take it at night with my other nighttime AEDs. When I started taking them, they were a bit difficult to swallow (narrow throat), but it got better over time. I just hope the Xcopri keeps working for me, unlike many other AEDs I've taken over the years that worked a few weeks or months, then stopped for some reason."

• Ano...
• Taken for 6 months to 1 year
• June 7, 2025

For Seizures "Used in combination with lamotrigine. Been seizure-free for 7 months. Side effect: lack of energy and sleepiness (sleep 9-10 hrs a night plus a 30-60 min nap). NOTE: I cannot recommend this drug - only a doctor can."

• Bel...
• Taken for 1 to 6 months
• July 2, 2025

For Seizures "Xcopri worked well to control my seizures until I was on 200 mg a day, and I ended up toxic and couldn't walk straight, needed help, you would've thought I was drunk. I don't drink. That was when I told my neurologist I was coming off it."