Auvelity for Major Depressive Disorder User Reviews (Page 4)

• 6...
• Taken for 6 months to 1 year
• September 4, 2023

"Six months on this medication. I have suffered from MDD for decades and meds have pooped out, especially when there is a trigger in my life that adds distress. I am still doing well. It took 2 months for it to really start working, but after 6 weeks I really enjoyed conversations again. Those who have diarrhea, I did too and it gets better. Discount card if you have insurance is a blessing. It being a brand new type of medication that targets glutamate should bring hope to many."

• SJM...
• Taken for less than 1 month
• September 3, 2023

"After 6 days, I feel less depressed & have more energy. I hope I can stay on Auvelity because I do have side effects of diarrhea with abdominal pain & an increase in tinnitus. I am taking 1 tablet a day."

• lit...
• Taken for 1 to 6 months
• September 1, 2023

"I've been taking this medication for six weeks. It is a life changer. If you also take ketamine infusions, 100% will change your life. I started experiencing some side effects like sleepiness probably after 3-3.5 weeks from the start. I am okay with this side effect. I didn't feel that good since 2005. Unfortunately, my insurance doesn't want to cover it anymore. Not sure what I would do without it. Tried many different prescriptions. ketamine infusions help, but they're crazy pricey, and you need to do it every four weeks. This medication is a game changer."

• Dre...
• Taken for 1 to 6 months
• August 30, 2023

"I've been on Auvelity for almost 2 months after taking Wellbutrin for 10+ years. Auvelity is vastly superior to Wellbutrin in my experience. Within a few days, I felt my heaviness lifting and a peaceful lightness emerging. I find joy and happiness in small things again and enjoy spending time with my kids, including one with serious special needs. Also, with the chaos that can occur with 4 kids, including 1 with severe autism, my level of agitation is greatly reduced with minimal yelling when they inevitably misbehave. I'm much more effective in staying calm and productively parenting. I feel a deeper connection with myself, others, and the world. My former intense anxiety is greatly reduced. I'm kinder and more compassionate. I've gone from about 8 drinks per week to no need to drink or self-medicate in 60 days. Auvelity is beyond an antidepressant, it's a physically and spiritually uplifting wonder drug."

• Dre...
• Taken for 1 to 6 months
• August 30, 2023

"I’ve been on Auvelity for almost 2 months after taking Wellbutrin for 10+ years. Auvelity is vastly superior to Wellbutrin in my experience. Within a few days, I felt my heaviness lifting and a peaceful lightness emerging. I find joy and happiness in small things again and enjoy spending time with my kids, including one with serious special needs. Also, with the chaos that can occur with 4 kids, including 1 with severe autism, my level of agitation is greatly reduced with minimal yelling, when they inevitably misbehave. I’m much more effective in staying calm and productively parenting. I feel a deeper connection with myself, others, and the world. My former intense anxiety is greatly reduced, I’m kinder and more compassionate. I’ve gone from about 8 drinks per week to no need to drink or self-medicate in 60 days. Auvelity is beyond an antidepressant, it’s a physically and spiritually uplifting wonder drug."

• gar...
• Taken for 1 to 6 months
• August 29, 2023

"Never felt better, cannot afford. Cost first time $95.00, second $95, third $114, and then off the wall $270.00! I can't afford to take it but I can't do without. Fixed income, 77 years old."

• Hoo...
• Taken for less than 1 month
• August 25, 2023

"I started taking Auvelity on Mon, 8/14/23. I was prescribed 1 tablet every 12 hours. I also take 200mg of sertraline daily and 10mg of buspirone daily. I felt my depression lift within 24 hours of starting Auvelity. This medication was amazing and I had a new outlook on life again, this time without the damaging side effects ECT. However, by Friday evening, 8/18, I was experiencing a severe headache, dizziness, nausea, and a 'high' feeling like I was on illegal drugs. On Saturday, I started feeling jerky movements in my muscles, and I was getting double vision. On Sunday, I was sent to the ER via ambulance. I had Serotonin Syndrome. This was NOT THE MEDICATION'S FAULT. My prescriber had not decreased my other SSRIs. On Monday, 8/21, buspirone was discontinued, and sertraline decreased to 50mg at night. Auvelity was changed to once daily. I know it's going to take a while for my body to adjust, but today is Friday, 8/25, and I'm feeling really 'loopy' and out of it."

• Kel...
• Taken for less than 1 month
• August 15, 2023

"I've been on Auvelity for 2 weeks now. I swear I felt a difference on day 1 but wanted to wait a while to see if it lasted or if I got any side effects. I can see the beauty in things again & catch myself smiling a lot. I've been majorly depressed since 2012!! This has been a life changer so far. I even have it in me to get up and take care of myself or complete a task that needs done. I'm almost back to who I was before the trauma and MDD. If you've tried a ton of other antidepressants that didn't work, ask your dr about Auvelity! Also, my anxiety has lessened greatly on this med. I don't take my Xanax as nearly as much as I used to before Auvelity. I also take Zoloft (200 mgs a day) still for depression."

• Amy...
• Taken for 1 to 6 months
• July 29, 2023

"I've been taking Auvelity for 5 months, and I can honestly say I have not felt this good in many years. I have had depression for 40 years. I know I'm still depressed to some degree, but the heaviness is gone. I can find joy easier. I'm rarely suicidal. I felt very weird, dissociated for about the first month. It was like I was walking beside myself and watching my life - I felt separate from the depression. It's very hard to explain. I'm just so glad I stuck with it. I would definitely recommend it. I had been taking Wellbutrin for years."

• Kim...
• Taken for less than 1 month
• July 26, 2023

"I have tried everything. After years of therapy, I finally admitted to my therapist, 'I wake up in terror and lay down to sleep in terror every night, and trust me, I know why.' It has been my baseline for 60 years, and I'm tired of climbing out of this hole every day. In November of 2022, my hole turned into a water well with my feet tied to the bottom, and the water was rising. I lost all interest in everything I loved! Why even be here? In 3 days on this drug, it was like an anvil had been lifted off my mind and soul! I had never felt this way, and I immediately called my doctor. He started laughing and said, 'That's what it feels like to be free of depression.' OMG, I have been on this for 2 weeks and I'm enjoying everything! Even cleaning my house!! My only regret is this wasn't available sooner. At 60 years old, I have started a new life! Watch out world, here I come!"

• Eri...
• Taken for less than 1 month
• July 20, 2023

"I have had MDD for 30 years and I’m 43. I was blessed with a HUGE surprise at 42 by getting pregnant with a vasectomy baby. About 5 months in PPD hit me hard. I was put on Lamictal and Trintellix in addition to Effexor, which I’ve been on for 13 years. It got me feeling “okay”. Then I gained 30 lbs in 2 months and was so angry all the time. I went off of the two, and a month later I couldn’t get out of bed again. I wanted to care for my son but I was just too despondent. I called my psychiatrist and told him I felt like giving up on life. I had been on 18 antidepressants, TMS, Ketamine therapy… I was a lost cause. He prescribed Auvelity and I really wasn’t feeling too positive about it. Today, I’m on day 11. And I cry with happiness. For the first time in 20 years, I feel normal. I can feel my emotions. I can sleep. I have energy. My intrusive thoughts are gone. My suicidal thoughts are gone. I hope this drug does for you what it did for me."

• Mar...
• Taken for less than 1 month
• July 14, 2023

"I've been on this drug for 2 weeks and every day is better. I actually get out of bed. I've tried several other rx and over time they go flat. I look forward to my continued improvement."

• sky...
• Taken for 6 months to 1 year
• July 10, 2023

"I had treatment-resistant depression. I happened to be on Wellbutrin in late 2018 (very little help) when I read about AXS-05. I added dextromethorphan (cough syrup at Walmart) at the ratio Axsome was using and improved greatly on day 2. The suicidal ideation I had had since at least age 6 disappeared. I obtained a prescription for Auvelity as soon as possible last fall. I did so mainly for safety concerns, but my mental health improved as well, again on day 2, to my surprise. I've never had any side effects. It saved my life (I'm a suicide survivor). I'm 71, I'll take it for the rest of my life."

• Mau...
• Taken for 6 months to 1 year
• June 28, 2023

"Transitioned to this after years on Zoloft (and seeing a major decline in effectiveness of the Zoloft over the last year). The transition was smooth compared to other med switches I've done - minimal nausea for the first 2-3 days and then no more undesirable side effects. I actually felt better so quickly I wondered if I was imagining the result because it did help with my depression within the first week, more so than the Zoloft ever had. I've been very, very happy and impressed with Auvelity these first 6 months and would absolutely recommend it if it's suitable for your conditions."

• ama...
• Taken for 1 to 6 months
• June 24, 2023

"My husband has suffered from treatment-resistant MDD, PTSD, and severe social anxiety his entire life. He is 64. He has tried every medication you can imagine, TMS treatments, and ketamine. We discovered Auvelity and immediately asked the psychiatrist about it. He had not prescribed it before but agreed to let him try it. He immediately started feeling an improvement. Now 4 months in, and he has zero anxiety and has stopped the diazepam. Says he has never felt the way he does now. He is out of bed early in the morning and out the door working, his appetite is back, the night terrors have stopped, and he can only guess that this is what 'normal' feels like. Something he has never felt before. I hope the medication continues working."

• Woo...
• Taken for 1 to 6 months
• June 23, 2023

"Unfortunately, it didn't work for my major depression. I was really hoping this would be the one. My depression is really hard to treat, so I don't know, it doesn't mean it won't work for someone else, though. No real side effects I noticed besides if you forget a dose. For me, it was mild withdrawal symptoms. Anyone who has discontinued a psych medication will know what I mean."

• jan...
• Taken for 6 months to 1 year
• June 4, 2023

"Helped with energy, anxiety, and having an interest in life again."

• kat...
• Taken for 1 to 6 months
• May 31, 2023

"I don't get it. I think it's very overrated, but that's just my opinion. I am disappointed, too, because I really wanted this to be it."

• jak...
• Taken for less than 1 month
• May 24, 2023

"From the first day, it worked well. It raised my spirits a lot and gave me energy, calmness, and the desire to do things."

• Kay...
• Taken for less than 1 month
• May 19, 2023

"I was very hopeful Auvelity would work for me, but unfortunately, I experienced the very rare serious side effects. The first day I took it, I felt dizzy and drunk with a small increase of anxiety. The next day I took it, I felt the same experience with added paranoia. I was in the middle of a busy Costco, so it was not fun (thankfully I didn't drive myself there). It made me feel so intoxicated that I could barely form sentences. I thought my body would be getting used to it, so I took it on day 3 after work. Holy hell, it took me on a ride. I was dizzy, felt drunk/high, anxious, paranoid, and now delusional. I thought my bf was mad and breaking up with me, but later confirmed that it wasn't remotely true. It takes a few hours to wear off, and after, I have poor memory of things that happened during. I had real mental clarity the next day that I haven't felt in years, so it's a shame I had to stop taking it. It's 100% worth a try, but don't drive until you know how it affects you! Good luck!"

• Rob...
• Taken for 1 to 6 months
• May 9, 2023

"At first, I thought I had found a winner. For the first few days, I was getting out for daily walks, more motivated with work, laughing more, and drinking a lot less - and no side effects! But then the benefits gradually disappeared, replaced by crippling insomnia and anxiety about a week after going up to two doses a day. I didn't sleep for four days straight; I was falling down walking to the bathroom and had double vision. It was really scary. I had to ask for a short course of Ativan or else end up in the ER. The insomnia resolved by dropping back to one dose, then the anxiety resolved immediately after discontinuation. Please be advised that there is no safe way to taper down from the starter dose (it's timed release), and most compounding pharmacies don't take insurance. So I got off cold turkey. I had only been on it a month, but after three days, I got brain zaps (manageable) for a couple of days, and anxiety and disorientation for several that have only just resolved. Good luck."

• Lui...
• Taken for 1 to 6 months
• May 6, 2023

"My 2nd review. I will say that it really has taken a good 8 weeks on this med to really start working along with everything else to maintain health. The quick 1-2 weeks, as advertised, may and probably helps very chronic or worse at the beginning. I have been on Zoloft and Seroquel ER for years. If you are trying this, hopefully, you will use the cost savings card. I take Auvelity 2 times a day. I gave it a 9 several weeks ago, moving it to 10. I have been on about every med out there. Don't give up. Give this a try, I think it is revolutionary."

• its...
• Taken for less than 1 month
• May 3, 2023

"I’ve recently added Auvelity to my repertoire of meds. Sertraline has been very effective for my anxiety, but I’ve still been struggling with depression. I’m about three weeks in, and I can definitely say I’ve noticed some improvements in my depression. I’d say it took close to three weeks before I noticed a response and not the one week it says. Side effects have been minimal, and I don’t notice any currently. So far, I’m happy, and I feel my depression lifting. Hoping this continues to work. Was on Wellbutrin for over a year and had no results with that. And tried a series of antidepressants, mood stabilizers, and antipsychotics."

• CTC...
• Taken for less than 1 month
• April 24, 2023

"For reference, I’ve been on Wellbutrin and Effexor for several years. I stopped the Wellbutrin when starting Auvelity and I just started weaning off the Effexor this weekend, so it’s too early to tell. However, since I do feel “lighter” already, I’m hopeful. The first couple of days at the full dose caused some dizziness and mania about two hours after taking, but both have decreased. I took the second dose a little later last night, and now I feel extreme fatigue, so I’m going to be more diligent about taking it earlier. The doctor said the side effects should go away soon, so I’ll update here. Again, I’m hopeful!"

• Mig...
• Taken for 1 to 6 months
• April 21, 2023

"Worked very well on me from the very first week. Works similarly to ketamine, without the hassle of taking a scheduled drug."