Auvelity for Major Depressive Disorder User Reviews (Page 3)

• Woofy
• Taken for 1 to 6 months
• June 23, 2023

"Unfortunately, it didn't work for my major depression. I was really hoping this would be the one. My depression is really hard to treat, so I don't know, It doesn't mean it won't work for someone else, though. No real side effects I noticed besides if you forget a dose. For me, it was mild withdrawal symptoms. Anyone who has discontinued a psych medication will know what I mean."

• jane
• Taken for 6 months to 1 year
• June 4, 2023

"Helped with energy, anxiety, and having an interest in life again."

• kathun
• Taken for 1 to 6 months
• May 31, 2023

"I don't get it. I think it's very overrated but that's just my opinion. I am disappointed, too because I really wanted this to be it."

• jako
• Taken for less than 1 month
• May 24, 2023

"From the first day, it worked well. It raised my spirits a lot, and gave me energy, calmness, and the desire to do things."

• Kay
• Taken for less than 1 month
• May 19, 2023

"I was very hopeful Auvelity would work for me but unfortunately, I experience the very rare serious side effects. The first day I took it I felt dizzy and drunk with a small increase of anxiety. The next day I took it I felt the same experience with added paranoia. I was in the middle of a busy Costco so it was not fun (thankfully I didn't drive myself there). It made me feel so intoxicated that I could barely form sentences. I thought my body would be getting used to it so I took it on day 3 after work. Holy hell it took me on a ride. I was dizzy, felt drunk/high, anxious, paranoid, and now delusional. I thought my bf was mad and breaking up with me but later confirmed that it wasn't remotely true. It takes a few hours to wear off and after I have poor memory of things that happened during. I had real mental clarity the next day that I haven't felt in years so it's a shame I had to stop taking it. It's 100% worth a try but don't drive until you know how it affects you! Good luck!"

• Robin
• Taken for 1 to 6 months
• May 9, 2023

"At first, I thought I had found a winner. For the first few days, I was getting out for daily walks, more motivated with work, laughing more, and drinking a lot less - and no side effects! But then the benefits gradually disappeared, replaced by crippling insomnia and anxiety about a week after going up to two doses a day. I didn't sleep for four days straight; I was falling down walking to the bathroom and had double vision. It was really scary. I had to ask for a short course of Ativan or else end up in the ER. The insomnia resolved by dropping back to one dose, then the anxiety resolved immediately after discontinuation. Please be advised that there is no safe way to taper down from the starter dose (it's timed release), and most compounding pharmacies don't take insurance. So I got off cold turkey. I had only been on it a month, but after three days, I got brain zaps (manageable) for a couple days, and anxiety and disorientation for several that have only just resolved. Good luck."

• Luigi
• Taken for 1 to 6 months
• May 6, 2023

"My 2nd review. I will say that it really has taken a good 8 weeks on this med to really start work along with everything else to maintain health. The quick 1-2 weeks, as advertised may and probably helps very chronic or worse at the beginning. I have been on Zoloft and Seroquel ER for years. If you are trying this, hopefully you will use the cost savings card. I take Auvelity 2 times a day. I gave it a 9 several weeks ago, moving it to 10. I have been on about every med out there. Don't give up. Give this a try, I think it is revolutionary."

• itsju...
• Taken for less than 1 month
• May 3, 2023

"I’ve recently added Auvelity to my repertoire of meds. Sertraline has been very affective for my anxiety but I’ve still been struggling with depression. I’m about three weeks in and I can definitely say I’ve noticed some improvements in my depression. I’d say it took close to three weeks before I noticed a response and not the one week it says. Side effects have been minimal and I don’t notice any currently. So far I’m happy and I feel my depression lifting. Hoping this continues to work. Was on Wellbutrin for over a year and had no results with that. And tried a series of antidepressants, mood stabilizers and antipsychotics."

• CTCin
• Taken for less than 1 month
• April 24, 2023

"For reference, I’ve been on Wellbutrin and Effexor for several years. I stopped the Wellbutrin when starting Auvelity and I just started weaning off the Effexor this weekend, so it’s too early to tell. However, since I do feel “lighter” already I’m hopeful. The first couple of days at the full dose caused some dizziness and mania about two hours after taking but both have decreased. I took the second dose a little later last night and now I feel extreme fatigue so I’m going to be more diligent about taking it earlier. The doctor said the side effects should go away soon so I’ll update here. Again, I’m hopeful!"

• Miguel
• Taken for 1 to 6 months
• April 21, 2023

"Worked very well on me and from the very first week. Works similarly to ketamine, without the hassle of taking a scheduled drug."

• Daisy
• April 16, 2023

"I have been on antidepressants all my life. I have taken all medications available in the market. I started Auvelity 3 days ago. I was tod to stop my two other antidepressants the day I started Auvelity. I have an enormous feeling of anxiety and despair. I am extremely depressed, unmotivated, flat affect I don't want to do anything except for to hide under the covers. The only problem is that my body won't allow me to relax because I have anxiety and restlessness. It's Sunday. I will stick with the medication but I think I feel worse"

• klb
• Taken for 1 to 6 months
• April 14, 2023

"Going to say this is the best medicine I have taken in a long time. Been on them all, and all stopped working as I'm very resistant to medicine. I'm very hopeful that Auvelity will be a game changer for me."

• skyler
• Taken for less than 1 month
• April 10, 2023

"I had just started taking this medication as I am diagnosed with Major Depressive Disorder, bipolar 2, and Generalized Anxiety Disorder. I was previously prescribed Fluoxetine (Prozac) for depression. After about 2 months of being on it, I started to wonder if it was even doing anything. I brought it up with my HCP and she recommended that I should try Auvelity. I had no issue with trying a new medication especially because after reading the reviews, people said that they almost saw a positive instantaneous reaction. The first day I had taken it I felt normal until around mid-day and that is when I had one of the most intense and genuinely terrifying panic attacks I've ever experienced. I could not breathe, or even speak and it felt like my heart was beating out of my chest. This luckily only lasted for about 30 minutes until I had calmed down. The second day was even worse. I was enduring intense and extreme, almost debilitating paranoia."

• aek
• Taken for less than 1 month
• April 6, 2023

"Unfortunately this medication made me really sick. The side effects described came on after 10-12 days on the full dose. Severe anxiety, loss of appetite, headaches. All came together with severity so be careful with this drug. I had never experienced this before and it was awful."

• Megan
• Taken for less than 1 month
• April 5, 2023

"My psychiatrist said a relatively new medication is helping patients like me. I've tried many anti-depressants over 12 long, frustrating years and never saw results that were anything better than slight improvement of some symptoms. Then even the tiny improvements would disappear after a few months. From what I've read so far about Auvelity, my current symptoms and psychiatric history are in line with the kind of patient this medication is designed to help. That being the case, I am writing this review the day before I begin taking Auvelity and want to update my experience in real time. In 12 years of seeking relief from overwhelming depression, this is the first I've ever heard of a depression medication that takes fewer than 8 weeks to show any results. I'm encouraged by the clinical results I've looked into. I'm giving a 10/10 rating because it won't allow me to not choose a number, and I don't want to drag the average down if this ends up being amazing. (If not, I will say so!)"

• Meshal
• Taken for less than 1 month
• April 5, 2023

"I am on week two now. I would say this medication works fast. I was so depressed but it changed the way I think and feel. No side effects for me but just on the first day, I felt nauseous. I like it for real. I will keep you updated guys."

• birdmom
• Taken for less than 1 month
• April 4, 2023

"I have been on just about every depression medication there is, and up until 5 days ago, was taking 5 different depression medications. They weren't helping much. Today I am on Day 5 of Auvelity. It has changed my life almost overnight. I feel 'normal' - no negative thoughts, no mood swings, no depression, very little anxiety. I was very skeptical about trying a new med, but I had to do something because life was not working for me. I am currently still on the lowest dose of 45mg/105mg. I have not noticed any side effects, which I was concerned about because I can be very sensitive to changes in my meds. I take one tablet first thing in the morning right now - it's very easy to use. I am not sure I really need to titrate up to two tablets a day at this point. I think Auvelity saved my life, it is truly miraculous how well it works! My thanks to Axsome, who developed this medication."

• Lifel...
• Taken for 1 to 6 months
• April 4, 2023

"I’ve been on many SSRIs, SNRIs, Wellbutrin, Lithium, Lamictal, Latuda, tried TMS, had 20 IV ketamine treatments. Ketamine worked the first round but not as well the second. Auvelity was a miracle drug for me. I cross tapered off Wellbutrin while dosing up on Auvelity and felt “high” for 10 days. Cut back to 1 Auvelity at night (off all other Wellbutrin at that point) and that did the trick. No side effects, appetite back, no anxiety, no depression. I haven’t felt this good in 20 years. Only taking 1 Auvelity, nothing else. Insurance covered after submitting a request. I’ve been taking it now for 3 months."

• Windw...
• Taken for less than 1 month
• March 30, 2023

"I've struggled with depression for 30 years. Over the years, many medications have helped, but many have not. Last May, I had been doing well for many years when a health condition derailed me. Changed some meds, did not work. There are so many things to implement to help one's depression, and medication is one of those. I have been on Auvelity for 3 1/2 weeks, started on a half dose, or one pill a day for three weeks, and increased to the normal dose yesterday. When depression "lifts", I can usually feel it lift. This medication has really helped me, I am encouraged. Don't be afraid to try this medication because it's something new, give it time. The one-week quick fix didn't really work for me, it's taken a good 14 days or so, but better than 8 weeks only to feel zero improvements. The health savings card really helps, it pays $4,000 per calendar year. The side effects have been diarrhea, but it's better, I don't feel jazzed up. I can focus better, humor is better."

• Rubbe...
• Taken for 1 to 6 months
• March 28, 2023

"I tried several different drugs that didn’t work very well for me and was starting to get frustrated. Auvelity began working within one week and has helped me IMMENSELY. I am finally able to get through the day without crying. My panic attacks have lessened. I am excited about my future (can’t remember the last time that happened). It is very expensive but there is a voucher to get it for $10! Search Auvelity $10 voucher/coupon and show it to your pharmacist"

• Muddl...
• Taken for less than 1 month
• March 24, 2023

"Switched two weeks ago from 450 mg Wellbutrin am to Auvelity am and pm. I also take Lamictal and Fetzima for depression, Vyvanse for focus, klonopin pm for anxiety, and Ambien, gabapentin, baclofen, and Vyepti for migraine prevention which have some interactions with my depression meds. My mood is definitely better as is my motivation beyond basics like getting dressed, eating, etc. I’m starting to handle more complex things and tackle important projects that my guilt, shame, and fear made impossible. My ability to think clearly and focus fades when the Vyvanse ends around 2p. Still struggling with other depressive symptoms and having strange side effects. Dizziness, eyesight problems, and lack of appetite. It’s like I move my head and my eyes are a second behind. Really tough. I get crazy sugar cravings every night. I’m hoping dizziness, eyesight, and cravings fade. Otherwise I like it a lot. Hate taking two times a day though. Insurance took 2 months despite my savings card!"

• Anonymous
• Taken for less than 1 month
• March 19, 2023

"I wrote a review previously on day 3. I wanted to give an update after day 10 since they advertise it to work by day 7. I rated it a 10/10 then, and I rate it a 10/10 now. I notice that I’m more productive and positive. I’ve kept up with cleaning the dishes, my apartment, and going to the gym. These things are easy for me to do when they once were a pain. I put away small stuff like my plate after I eat instead of just letting it sit there. The only negative thing that I’ve noticed is that at the 6-7 hour mark after taking the first dose, I develop a headache, and I can tell that the medication is wearing off. Auvelity requires you to take two doses a day 8 hours apart. I kind of notice the depression seeping through at around the 7-hour mark, but then it goes away again when I take the 2nd dose. I have PTSD and this med also quiets the ruminating thoughts and hypervigilance."

• Ejariah
• Taken for 6 months to 1 year
• March 18, 2023

"This is hands down the most effective antidepressant on the market today. Saw major improvements within 3 days of taking this medication. Nothing of its kind out there and really blows the other medications out of the park. If you have treatment resistant depression I would recommend Auvelity to anyone. It makes you see life on a whole new level"

• Jpal
• Taken for 1 to 6 months
• March 18, 2023

"Took for 3 months . Started asking if there were people in the house . Stopped taking and feeling very lightheaded. Did not work for me ."

• My...
• Taken for less than 1 month
• March 13, 2023

"I haven’t ever made a review on antidepressant medication because none ever wowed me. I’ve tried multiple SSRIs and SNRIs: Prozac, Zoloft, Effexor, Wellbutrin, Paxil. Effexor and Prozac helped a bit for me but nothing close to “clinically significant changes”. I have been on Auvelity for only 3 days and I am noticing from day one a change in my mood, outlook, and motivation. They have all improved. I have PTSD and a long history of trauma. Before the trauma, I used to look at small things and find beauty in it… I would smile at little things. Trauma changed all that. But after just 3 days on Auvelity, I feel there’s beauty in the world again. I went to the grocery store and saw this little chick plush toy which was so fuzzy and cute and I actually smiled at it. Something so small put a smile on my face. I feel like Auvelity has brought my soul back. I am excited for hitting day 7 on this med. I have Medicaid and they paid for Auvelity."