Alirocumab User Reviews & Ratings (Page 2)

• Girl...
• August 23, 2017

Praluent (alirocumab) for High Cholesterol "I am a statin Intolerant patient who was initially excited to try this new drug. Was easy to administer and seemed to be working with little side effects (minor cough and cold symptoms). Total Cholesterol went from 203 to 98 after just two months. As I continued to use the drug developed severe shortness of breath and heart palpitations. Sadly apparently I can't tolerate this drug either. After further research, there is little research on long term side effects. My pharmacist told me that patients are reporting my same symptoms and even memory loss. Not the drug for me."

• firefly
• Taken for 1 to 6 months
• October 3, 2019

Praluent (alirocumab) for High Cholesterol, Familial Heterozygous "Anyone taking Praluent with side effects of Leg Pain followed by Varicose Veins spreading throughout your legs (at the site of injecton)? Also pigmented white spots appearing? Also lung issues? Lastly, extreme joint pain?"

• Melly
• Taken for 1 to 6 months
• March 27, 2018

Praluent (alirocumab) for High Cholesterol "I'm a 53 yes old female, I've had two heart attacks back in 2015. Also diabetic and other chronic illness. My doctor prescribed this medication about four months ago, at first I didn't take it something made me weary. I don't tolerate statins. Just this week took my third dose. The side effects are horrible the pain is unbearable. My memory is a mess. I can't literally hold a cup in my hands. Lower back pain, legs are weak if I move an arm it feels like it's being broken , my shoulders hurt my neck hurts, literally I'm not able to function at all. I will not take this medication ever again calling my doctor tomorrow and letting him know, that I'm practically in pain 24/7. I refuse to be this ill."

• Jwano
• Taken for less than 1 month
• November 20, 2020

Praluent (alirocumab) for High Cholesterol "Horrible. It has been 6 days since I could function. Severe neck & sinus pain. Arms so tired I can barely lift them. No fever. Bronchial pain & short of breath. Dr said wait it out. Wait 3 weeks before next dose. There will NOT be another dose."

• NUM-NUM
• Taken for 1 to 2 years
• April 11, 2020

Praluent (alirocumab) for Cardiovascular Risk Reduction "I started Praulent about a year ago... loved the results LDL from 135 to 69 just awesome. I first noticed a tightness in my chest and diaphragm, as I continued to take it I notice increased difficulty in breathing deeply and freely. There was the loss of stamina and increased fatigue. I used up my supply of Praulent 5 weeks ago... restricted breaths stopped about 2 weeks ago. SCARED about going back on Praulent with corona virus approaching. I'm 69 years old that battle will be hard enough... Restart Praulent... YES or NO? I JUST DON'T KNOW!"

• GPano
• Taken for 1 to 6 months
• August 10, 2019

Praluent (alirocumab) for Cardiovascular Risk Reduction "I am three shots in or 5 weeks. Progressive muscle and joint pain. Muscle cramps. Rapid heart beat and palpitations. Brain fog. Burning eyes. Dry nose. Stuffy nose. Hoarse voice. Horrible GERD for several days post injection. No more for me. This stuff is horrible."

• Fathe...
• Taken for 1 to 6 months
• April 7, 2016

Praluent (alirocumab) for High Cholesterol "My dad is taking this med as no Statin drug was tolerable for his high cholesterol. As other reviewers have noted, his LDL decreased quickly from 144 to 34. However; his HDL also had a significant decrease. It is now 34. We have a concern with this medication lowering both "good" & "bad" cholesterol. I think all individuals using this med are part of a bit of a continued experimental process given the controversial recent approval by the FDA to release. Sharing info on sites such as this can be useful. Please share feedback if others have similar experiences. My dad's doc told him to return in 2 months. He didn't seem too concerned about the low HDL number."

• Frmr...
• Taken for less than 1 month
• April 30, 2016

Praluent (alirocumab) for High Cholesterol "My Cardiologist prescribed Praluent to control cholestoral. I had one injection in October of 2015. within 24 hours my joints swelled to the point where for example I could not safely grasp my steering wheel. My B/P rose by 52 points to 191/ 106. My Cardiologist made no diagnosis outside of it might not be the Praulent, but began to try every drug that was available. My new normal B/P is 161/98. I have contacted the manufacturer talked generlities for an hour,who cordially let me speak with their research person and we but was unable to get any list of could be's or look for's. After perusing the Internet today, I find that the injection could have caused Vasculitis or Immunogenicity."

• Elle
• Taken for 1 to 6 months
• September 16, 2019

Praluent (alirocumab) for High Cholesterol, Familial Heterozygous "The Praluent injections gave me a runny nose, chest muscle pain, and I would cough up little chunks of clear phlegm for a few days after every injection. Then the muscle pains and fatigue would set in until time for the next shot. Rinse and repeat. However, my cardiologist was ecstatic with my blood work. I had been on the injections for a couple of months when I got a real bad case of pneumonia and could do nothing but lay in bed and cough phlegm for 3 weeks. I went off the injections during this time. After 4 weeks of no injections I got blood work done and it was absolutely horrible, so now of course I'm back on it just praying the muscle pain goes away and that I don't get pneumonia again. This is the only medication I have ever taken that I am afraid might kill me. But my cardiologist thinks it's a freaking miracle drug."

• jhb
• Taken for 6 months to 1 year
• January 11, 2023

Praluent (alirocumab) for High Cholesterol "After second injection the medicine made sores on my back which is now scars. At the eighth month I was developing arm pain and hands going numb. At ten months I lost the ability to perform any physical manual labor lots of pain in arms hands going numb at night it was worse. I am a hard worker and I could not pick things up hand no strength in my hands severe pain in my arms and hands. Contacted my Doctor finally. She done lots of blood work and everything was ok with that. I was advised there was no explanation for the pain I was going through. I am on no meds other than Praleunt I found and article on journal of Neurology Research that described exactly what I was experiencing from what a 57 year old woman went through and was diagnosed with (cidp) as an exclusion diagnosis. Praleunt is pure poison for me at least. I have never hurt so bad in my life and just hope there is no permanent damage. I have not taken an injection for 3 weeks now and still hurt with numb hands and arm."

• NJG
• November 14, 2019

Praluent (alirocumab) for Cardiovascular Risk Reduction "Took one dose of Praluent @ 3:00pm and had a massive flush of symptoms throughout my whole body 15 minutes later. At the ER at 4:00 given steroids shot, benadryl shot and finally epinephrine to stop the reaction 4 hours later. This is toxic and poison! It should be taken off the market."

• Nancy
• Taken for 1 to 6 months
• October 1, 2019

Praluent (alirocumab) for High Cholesterol, Familial Heterozygous "62 yr-old female with heterozygous familial on statins - 20 mg Crestor - and ezetrol. After strict diet and exercise total cholesterol down from 6.8 to 2.1. Started on praulent bi-weekly in June. Although my LDL plummeted to 0.06, severe muscle spasms, pain and cramps kept increasing: knee, thigh, ankle, next leg and eventually upper arm. No more gym, Chronic pain, sleepless nights, painful to stand or walk. Requested to be taken off a week ago. 3 weeks since my last shot and improving each day. Please God let the statins work better."

• Mike
• Taken for 5 to 10 years
• September 23, 2020

Praluent (alirocumab) for High Cholesterol, Familial Heterozygous "Had a heart attack 5 years ago at 38 years old due to hypercholestrolemia. Statins wrecked my body up until this came out. I’m allergic to almost everything so I was happy to hear that this medicine didn’t have bad side effects for most people. This medicine has literally saved my life. Ive had normal levels for a while now. The only noticeable thing I get is occasional urinary sensitivity. Surprised to see all the negative comments. This medicine costs me nothing."

• FtMye...
• Taken for 1 to 6 months
• March 4, 2016

Praluent (alirocumab) for High Cholesterol "I have experienced debilitating leg pain, brought on by simple walking, and not sure if related to Praulent. Began shortly after first injection and had increased in severity. Have seen many doctors without success. Any advice to Mike.schrider@jlodge.com. Thanks"

• CMano
• February 18, 2020

Praluent (alirocumab) for High Cholesterol "I was on a statin for several years, but in 2015 I had to have 2 stents put in. When cardiologist increased the statin I had side effects so had to stop it. She urged me to try Praluent saying it had little to no side effects. After 4 doses I got a UTI that didn't respond to the usual antibiotics and I ended up in hospitals for stronger antibiotics. Then a few weeks later I developed pain in my neck muscles that got so bad it woke me up, also had pain in hips and legs. Been off the medication for 3 weeks and symptoms have all but disappeared. Only good thing was my collateral went down almost 100 points."

• Anonymous
• Taken for 1 to 6 months
• October 14, 2021

Praluent (alirocumab) for High Cholesterol "Horrendous. I called the FDA. I had side effects of horrendous fatigue, flu like symptoms, muscles hurt feel very weak, muscle skeletal issues, burning, bad sinuses, tired, tired ,diarrhea after 4th bi weekly injection and insomnia. I was on a great path before this, my diet is good, I was active, now I can’t do walking and treadmill because I just feel horrible. To walk up stairs my legs feel so heavy. Would not recommend this to anyone. What’s the be point in having great cholesterol numbers if your quality of life is horrible. I’m just waiting for this stuff to leave my system. And praying it does no long term damage."

• Unhappy...
• Taken for 1 to 6 months
• August 17, 2020

Praluent (alirocumab) for High Cholesterol "So I have been on Praluent for a month. I was previously on Repatha doing great, however my insurance doesn't want to pay for that and made me switch. 2nd dose now have UTI, muscle pain and daily headaches. I go to my doctor in 2 weeks and see if I can go back to Repatha. I thought from the reviews they are the same however theses side effects are telling otherwise. Btw both give me stuffy nose but I can live with that one. The other side effects were what I had being on statins and this is the low dose of Praluent."

• Krisvb
• Taken for 1 to 6 months
• September 24, 2016

Praluent (alirocumab) for High Cholesterol "Praulent dropped my cholesterol quickly and significantly. Unfortunately, the last 3 injections have been followed within a couple of hours by a rapid, irregular heart rate. Has anyone else experienced this "side effect"?"

• Frida
• Taken for 1 to 2 years
• December 24, 2018

Praluent (alirocumab) for High Cholesterol "Dramatic reduction in total cholesterol after about 1.5 years. 62 year old female. Went from 250 down to now 107. Have gradually been getting more and more fatigued, weaker and now to the point I can't do my walks. Going to call cardiologist after the holidays. This is how I felt on statins after just a few days. I'm disappointed. Very easy to use med."

• Badge
• Taken for 1 to 6 months
• February 20, 2016

Praluent (alirocumab) for High Cholesterol "So far this drug is amazing! I did my first injection of 75 mg on 1-6-2016. I had a lipid panel drawn on 1-8-2106 to see what my starting base line will be. In the 48 hours between the injection and the lipid panel, the results were nothing less than miraculous. My total cholesterol went from 222 to 170, LDL from 152 to 96! I can't wait to see the results at 30 days and on. The self injection was virtually painless and quick. I didn't even have any injection site reactions like swelling or redness and I always have those side effects from almost all shots. I'm not on the Pralulent payroll, just a 68 year old man who couldn't take statin's and now have a great alternative drug. I hope you have the same results as I have.."

• Don...
• Taken for less than 1 month
• September 11, 2015

Praluent (alirocumab) for High Cholesterol, Familial Heterozygous "Gave myself the first injection using the Pen earlier this week. The injection was automatic. Pressed it against my skin, pushed the button, the mechanism clicked and the injection was made. When finished the mechanism clicked again which withdrew the needle. It was almost painless. Will repeat in two weeks and get blood tests in a few months to see if it works."

• RSU
• Taken for 1 to 2 years
• January 6, 2018

Praluent (alirocumab) for High Cholesterol "started Praluent 9/2015. Began cough/cold symptoms 1/2016. Injection every 2 wks. Symptoms got worse each time med was injected. 7/2016 Informed my Dr who said symptoms were unrelated. Between 8/2016 and 1/2017 went to the ER 5 times and spent 20 days in hospital. Bronchitis and autoimmune reaction. The med reduced LDL and destroyed my immune system. Had to receive infusion and still have very low IGG. Once I stopped it Took all of 2017 to start feeling a little better. Reported reaction to mfg and FDA. Thinking about seeking litigation advice."

• elena
• Taken for 1 to 6 months
• October 21, 2021

Praluent (alirocumab) for High Cholesterol "My mum (76) took Praluent 75 for some months and in a short time started complaining of elevated BP and feeling of ear pressure, something she never suffered before. After some months her total cholesterol showed a marginal reduction (200) but also a CPK elevation (245). Be aware of with this drug, it is still quite experimental, doctors will mostly deny its side effects as do the leaflets but they are all there ! Doctors only care of studies with a control group, but please also listen to the actual experiences from patients !!"

• Alexa...
• Taken for 6 months to 1 year
• May 5, 2020

Praluent (alirocumab) for High Cholesterol, Familial Heterozygous "Praluent did a great job of lowering my cholesterol. In fact it lowered my LDL to below normal readings. Unfortunately I developed chronic, painful side effects. I had deep bone and muscle pain that kept me up through the night. High doses of Advil and Zoplicone couldn't address the pain and allow for sleep. It's been three months off this drug and I'm able to sleep 6 hours with no medication. The bone pain I was experiencing is much reduced and doesn't set in until the morning. I will be relieved when my system is completely free of this drug."

• HAPPY...
• Taken for 5 to 10 years
• December 14, 2023

Praluent (alirocumab) for High Cholesterol "Been taking since it was experimental, over 5 years now with NO side effects before taking bad cholesterol was near 300 after the test it was around 50. I do and have recommended this medicine, it is a very GREAT med!"