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Acetaminophen / diphenhydramine for Headache User Reviews

Brand names: Tylenol PM, Percogesic Original Strength, Midol PM, Pain Reliever PM, Headache Relief PM, Unisom PM Pain, Non-Aspirin PM Extra Strength, Percogesic Extra Strength, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Wal-Nadol PM Extra Strength, Excedrin PM, Headache Formula PM, Legatrin PM, Tylenol Sore Throat Nighttime, Pharbetol PM Acetaminophen PM Extra Strength Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime Anacin PM Aspirin Free …show all brand names

Acetaminophen / diphenhydramine has an average rating of 7.1 out of 10 from a total of 14 reviews for the treatment of Headache. 71% of reviewers reported a positive experience, while 29% reported a negative experience.

Acetaminophen/diphenhydramine rating summary

7.1/10 average rating

14 ratings from 17 user reviews.

Compare all 260 medications used in the treatment of Headache.

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Reviews for Acetaminophen / diphenhydramine

  • lfsilva
  • October 1, 2009

Tylenol PM (acetaminophen / diphenhydramine) "This worked for a while then I started getting rebound headaches. I was waking up to excruciating headaches in the mornings after taking these at night after a period of time. They can increase with intensity over time. If you find this happening to you. You need to get off of them. They are rebound headaches."

1 / 10
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33 Report
  • Lexi
  • Taken for less than 1 month
  • June 27, 2020

Tylenol PM (acetaminophen / diphenhydramine) "I hate this stuff. I took it at around 10:30pm and it did not help me sleep at all. I have been tossing and turning the whole night and having the most stressful, fast dreams. I woke up completely soaked in sweat even. I also am now awake at 5am (at least the third time I’ve woken up throughout the night) and my nose and throat are drier than the Sahara desert. I also have a heinous headache. I cannot wait until this stuff wears off so I don’t have to feel so dry and uncomfortable anymore."

1 / 10
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12 Report
  • Anonymous
  • August 22, 2008

Percogesic Original Strength (acetaminophen / diphenhydramine) "I remember back when you could only get Percogesic by prescription from a doctor. Nowadays when a prescription is approved to be sold over the counter, the strength of the medication is greatly reduced, which makes it much less effective. I suffer from migraine headaches on a regular basis and am a devoted user of Percogesic, as I have found it alleviates the pain much faster than a lot of the expensive prescription medications I have tried. The only problem is that Percogesic is getting more difficult to find in the stores, so I make sure to stock up whenever I find it!"

10 / 10
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20 Report
  • Beba
  • August 30, 2013

Percogesic Original Strength (acetaminophen / diphenhydramine) "They also have the extra strength Percogesic. I LOVE it. I keep a bottle in my purse all the time. My dr is afraid to write a prescription for anything stronger than a Tylenol, so I have to depend on the Percogesic for my very frequent headaches!"

10 / 10
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11 Report
  • White...
  • March 19, 2008

Percogesic Original Strength (acetaminophen / diphenhydramine) "I get severe headaches and occasional migraines. Percogesic seems to be the ONLY thing that helps with the pain. I've tried prescription medications for treating migraines, including imitrex, and others. Nothing seemed to help as much as the percogesic, another good thing is that I don't experience any terrible side effects like I have with migraine medictions. I'd highly recommend this. I also take a few times per year (at most) to ease my cramps during my period when the pain is crippling."

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15 Report

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  • Anonymous
  • March 22, 2009

Tylenol PM (acetaminophen / diphenhydramine) "I ocasionally use Tylenol rapid release during the day and recently developed cold and flu, so I decided to try Tylenol PM at night for better sleep. Make sure to read the drug interactions first, as I spent two restless nights with nervousness. Many of my friends take this product, so I'll pass it on to them, but if you are on other medication, check the list of side effects."

1 / 10
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14 Report
  • Pained...
  • Taken for 10 years or more
  • October 10, 2017

Percogesic Original Strength (acetaminophen / diphenhydramine) "In my earlier years I had severe migraines. I found that percogesic was very effective in lessening the severity of these. I am 78 now and in 4th stage kidney failure so I am very limited in what OTC products I can safely take. I take a prescription pain med regularly for pain from a bad knee replacement plus 2 hip replacement and severe arthiritis. I take percogesic for headaches since my pain meds do not help them while percogesic will usually stop them. I am very pleased that percogesic still does the job for me."

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7 Report
  • car
  • November 20, 2012

Percogesic Original Strength (acetaminophen / diphenhydramine) "I have severe migraines and Percogesic over the counter helps like no prescription medicine. I first tried this from a sample at a chemist in 1973. I have kept it in my cabinet since. Now I cannot find it. My bottle is out of date and am so worried. "

10 / 10
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10 Report
  • Anonymous
  • August 16, 2008

Percogesic Original Strength (acetaminophen / diphenhydramine) "I tried percogesic for the first time when I had a recurring headache for 5 days. I tried everything to relieve the pain and nothing worked. A friend told me about percogesic and I bought some. My headache was relieved and I was able to sleep all night! It really works and I would definitely recommend it!"

10 / 10
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12 Report
  • green...
  • January 8, 2016

Excedrin PM (acetaminophen / diphenhydramine) "I tried the cheap brands they made me sick, so I went back to Excedrin works great. It's like a car - you can save and get a cheap one with cheap results or pay a little more and get something that performs great. This brand is the good one - I'd invest in thier stocks"

10 / 10
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3 Report
  • cmwil...
  • October 20, 2011

Percogesic Original Strength (acetaminophen / diphenhydramine) "I get migraines and its hard to get a medication that actually helps it. This helps sinus headaches as well."

9 / 10
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18 Report
  • the...
  • February 7, 2010

Tylenol PM (acetaminophen / diphenhydramine) "I really enjoy taking this when I'm hurting and all I want is to go to bed. Works like a charm for me."

8 / 10
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20 Report
  • Anonymous
  • December 7, 2011

Percogesic Original Strength (acetaminophen / diphenhydramine) "This pill is great. It's the only one I'll take for a headache!"

9 / 10
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12 Report
  • moone...
  • April 14, 2008

Percogesic Original Strength (acetaminophen / diphenhydramine) "I started using Percogesic 8 years as friend of mine recommended this for my headaches. This is the only medicine I use for headaches an it's great!!!!"

10 / 10
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8 Report
  • catryna
  • January 30, 2010

Excedrin PM (acetaminophen / diphenhydramine) "Back in January of 2004, I had a terrible migraine that would not go away. I finally took Excedrin PM, so I could sleep. I had a convulsion and I have had double vision ever since."

1 / 10
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5 Report
  • Mary
  • May 13, 2008

Excedrin PM (acetaminophen / diphenhydramine) "The only pill I take for headaches, pains and insomnia and I wouldn't change it."

10 / 10
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4 Report
  • Anonymous
  • March 11, 2009

Excedrin PM (acetaminophen / diphenhydramine) "I use it sometimes at the onset of a migraine. It helps me relax and fall asleep without the side effects of a stronger migraine medication."

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3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.