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Orencia User Reviews & Ratings (Page 3)

Orencia has an average rating of 6.0 out of 10 from a total of 71 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Orencia

Commonly mentioned side effects
  • Sti...
  • Taken for 1 to 6 months
  • November 14, 2022

For Rheumatoid Arthritis "These infusions put me in the hospital twice (for the first time in my life!) with high blood pressure and damaged my heart. I had never had a blood pressure problem, and it was because of the daily notes I keep that I finally made the connection between the BP issues and the dates I had received the infusions, and the infusions were stopped. I have not had a blood pressure problem since, but the damage to my heart remains."

1 / 10
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8 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 23, 2014

For Juvenile Idiopathic Arthritis "My daughter started monthly Orencia infusions for her juvenile idiopathic arthritis about 3 years after being diagnosed. She had been previously taking Enbrel and methotrexate injections weekly for 3 years. Her arthritis became more aggressive, so her rheumatologist started her on Orencia (continuing the methotrexate injections). She got used to the infusion part rather quickly. She had no side effects at all, and the only problem we had was the occasional blown vein. Unfortunately, the medication did not prove to be effective for her. After 8 months of constant flare-ups, oral steroids, and steroid injections, we decided to change the medications again. There are, however, 2 other children we know that Orencia is helping prevent flare-ups."

7 / 10
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21 Report
  • mic...
  • Taken for 6 months to 1 year
  • September 3, 2021

For Rheumatoid Arthritis "I liked this drug although it didn't stop my wrist pain. I had weekly injections and besides some issues with fatigue and diarrhea, it was pretty good. I was taking it with Plaquenil as well. My rheumatologist has switched me to Rinvoq, so we will have to see. Rinvoq has poor reviews, so I am a little scared."

8 / 10
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8 Report

Frequently asked questions

  • Min...
  • Taken for less than 1 month
  • September 19, 2021

For Psoriatic Arthritis "I have just had my second infusion of Orencia. The first go-around, I had a headache and fever and aches for that night and most of the next few days. After the second dose, I have severe aches and pains in all joints and muscles, and my skin hurts to touch it. Plus, I have a cold or something that just came on a day after the infusion. I am wondering if it is going to work for me or if I need to change. I was on Simponi Aria for a year and a half, and then it stopped working. My question is, are these symptoms considered bad, or something that I have to put up with and hope they go away and the Orencia starts working without these side effects?"

2 / 10
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7 Report
  • Chr...
  • Taken for less than 1 month
  • November 16, 2021

For Psoriatic Arthritis "40 yr old woman with psoriatic arthritis. I have already tried methotrexate (did not work), Humira (too much fog brain), Enbrel (worked great but my body developed immunity), and now I am on Orencia. Week 1, I noticed some slight belly ache as if I did 2,000 sit-ups. Week 2, it got slightly worse. Week 3, the pain in my upper left abdomen has gotten so bad it's hard to sleep. I also have some severe lower abdomen pain, so I am hoping this gets better soon. I was off medication for 4 weeks, which caused some serious flare-ups. Since I started Orencia, one of my major flares is slowly subsiding, while I have developed 2 new issues (knees & foot). Hoping after some time this gets better. PS- It was very nice they provided a co-pay card for the $1,000 out-of-pocket upon request."

4 / 10
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  • Not...
  • Taken for 1 to 6 months
  • March 24, 2025

For Rheumatoid Arthritis "I started Orencia four weeks ago after Humira and Enbrel did nothing for me. I'm taking it with methotrexate. I get hit with nausea and diarrhea for like a day or two after my dose. I've had a flare for the past two months now, and I really need this stuff to start working."

5 / 10
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  • Dug...
  • July 27, 2020

For Rheumatoid Arthritis "This Orencia took about four months to work for my RA. I have zero pain and good mobility. Been taking it for a year and am 71 years old."

8 / 10
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52 Report
  • Don...
  • Taken for 1 to 2 years
  • February 27, 2020

For Rheumatoid Arthritis "The best drug I have been on! It gave me my life back!"

10 / 10
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41 Report
  • 5te...
  • Taken for 6 months to 1 year
  • March 9, 2017

For Rheumatoid Arthritis "LIFE CHANGING - I have tried many of your typical RA drugs since being diagnosed at 22 (Plaquenil, Methylprednisolone for 5 years)."

10 / 10
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44 Report
  • Nor...
  • Taken for 1 to 2 years
  • May 5, 2016

For Rheumatoid Arthritis "Gave this drug a ten a few months ago, but after just over a year, it has stopped working. Now trying Roactemra."

3 / 10
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  • Anonymous
  • Taken for 5 to 10 years
  • September 12, 2023

For Rheumatoid Arthritis "It's awesome. I've been on it for 7 years, I play tennis 5 times a week with no problems. I call it bionic."

10 / 10
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10 Report
  • Nan...
  • Taken for 1 to 2 years
  • March 30, 2020

For Rheumatoid Arthritis "Been on a monthly infusion for almost 16 months. Works well. But now I have severe nerve pain in my arms and ankles."

6 / 10
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23 Report
  • BW8...
  • Taken for 1 to 6 months
  • March 15, 2014

For Rheumatoid Arthritis "Limited improvement after 4 months, developed a bad rash, and MD refused to continue medication."

2 / 10
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42 Report
  • Lon...
  • Taken for 1 to 6 months
  • April 14, 2022

For Rheumatoid Arthritis "This drug almost killed me. Do not use. I was so sick. My gastrologist said to get off immediately. He had other patients with the same problems."

1 / 10
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13 Report
  • Chi...
  • Taken for 2 to 5 years
  • June 28, 2018

For Rheumatoid Arthritis "I am scared to quit Orencia and am getting no benefit from it. What a waste."

1 / 10
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26 Report
  • Ann...
  • Taken for 6 months to 1 year
  • April 25, 2018

For Rheumatoid Arthritis "Orencia worked a little, maybe taking the pain down from 8 to 6, but it did not get rid of the sacroiliac joint (SI) joint pain I had ever, so I went on to try another medicine from my rheumatologist."

1 / 10
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18 Report
  • 17c...
  • Taken for 1 to 6 months
  • February 27, 2018

For Rheumatoid Arthritis "It made me extremely nauseous."

2 / 10
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20 Report
  • Tje...
  • September 17, 2023

For Rheumatoid Arthritis "My arthritis has not progressed any further. Psoriasis has still given me patches."

9 / 10
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5 Report
  • Cat...
  • Taken for less than 1 month
  • January 20, 2023

For Rheumatoid Arthritis "I experienced severe leg cramps for 24 hours after taking it. Would not recommend it."

2 / 10
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5 Report
  • cad...
  • Taken for 6 months to 1 year
  • February 17, 2017

For Juvenile Idiopathic Arthritis "I loved it 'til I had my first reaction after 8 months using it. My life has improved."

7 / 10
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9 Report
  • Mar...
  • November 17, 2021

For Rheumatoid Arthritis "I have had 3 self-injections of Orencia. I am waiting patiently for results in my knee."

6 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.