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Orencia and Nausea: What Users Say

Nausea: mentioned by 6 users (8.5%)

Based on user experiences from 71 Orencia reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 11.3%
nausea 8.5%
tiredness 8.5%
fatigue 7.0%
diarrhea 5.6%
dizziness 5.6%
headaches 5.6%
back pain 4.2%
mouth sores 4.2%
rash 4.2%

Reviews for Orencia

Commonly mentioned side effects
  • Ore...
  • Taken for 1 to 6 months
  • May 15, 2019

For Rheumatoid Arthritis "I am a 49-year-old male. I was diagnosed with RA in 1997. I was on Humira for 10 years, which helped greatly, but the side effects began showing, so I was forced to stop. I was off all RA meds for a couple of years, and my condition began deteriorating again. I went on Orencia IV drip. I began showing almost all of the side effects listed about a month after my first dose. It was slowly poisoning me. I was sick all the time and showing severe symptoms: exhaustion, night sweats, back pain, migraines for 8 days straight, diarrhea, nausea, and a level of discomfort I've never felt. It's an awful medicine with crippling side effects. It is important to note that the side effects were worse than the RA itself, and my condition is moderate to severe. My suggestion is to avoid this medication at all costs. I was put on an anti-nausea pill that is used for chemo patients. If you do some research, you will find that 25% of the people on Orencia have a bad experience."

1 / 10
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  • jvp...
  • Taken for less than 1 month
  • July 15, 2015

For Rheumatoid Arthritis "I have taken 4 doses of the weekly self-injections. At first, I felt awful, nauseated, and flu-like symptoms, but now I feel wonderful. I don't hurt, and it even has helped the shortness of breath I would get walking up stairs. I hope it continues to help and hope I don't gain additional weight as I have done with the prednisone. I have been on prednisone for over 6 months and have gained 10-15 pounds."

9 / 10
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98 Report
  • Kat...
  • May 29, 2017

For Rheumatoid Arthritis "After rashes, pain, nausea, and elevated liver enzymes on Remicade, then Humira, the doc switched me to Orencia. Felt very tired the evening of the loading dose, but not ill. Now I feel better than I have felt in 4 years! LOVE this stuff!"

9 / 10
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81 Report

Frequently asked questions

  • Jay...
  • Taken for 1 to 6 months
  • January 7, 2021

For Rheumatoid Arthritis "I was on Enbrel for over 15 years for RA. Shortly after I started on it, I told my rheumatologist it was a miracle drug. I still had flares, but the severe pain I had felt every day was pretty much gone. Then, after so many years, the pain started returning. My current rheumatologist switched me to Humira. After a month, it seemed to be helping. But I was having nausea and a continuous headache with occasional dizziness. It was so bad I asked my rheumatologist to switch me to something else. She then put me on Orencia. I've been on it for 6 weeks, but the pain I had before going on Humira has returned. And I also have nasal congestion 24/7. I'll give the Orencia a few more weeks, until my next appointment with my rheumatologist, and if the pain and congestion aren't any better, I'll see what she wants to do. As a side note, I've also been taking methotrexate for 15 years."

4 / 10
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30 Report
  • Not...
  • Taken for 1 to 6 months
  • March 24, 2025

For Rheumatoid Arthritis "I started Orencia four weeks ago after Humira and Enbrel did nothing for me. I'm taking it with methotrexate. I get hit with nausea and diarrhea for like a day or two after my dose. I've had a flare for the past two months now, and I really need this stuff to start working."

5 / 10
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  • 17c...
  • Taken for 1 to 6 months
  • February 27, 2018

For Rheumatoid Arthritis "It made me extremely nauseous."

2 / 10
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20 Report

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