Generic name: Methylprednisolone Injection [ meth-il-pred-NIS-oh-lone ]
Brand names: A-methapred, Solu-Medrol
Drug class: Glucocorticoids
Medically reviewed by Drugs.com. Last updated on Jul 18, 2022.
Uses of Solu-Medrol:
- It is used for many health problems like allergy signs, asthma, adrenal gland problems, blood problems, skin rashes, or swelling problems. This is not a list of all health problems that Solu-Medrol (methylprednisolone injection) may be used for. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Solu-Medrol?
For all uses of Solu-Medrol (methylprednisolone injection):
- If you have an allergy to methylprednisolone or any other part of Solu-Medrol (methylprednisolone injection).
- If you are allergic to Solu-Medrol (methylprednisolone injection); any part of Solu-Medrol (methylprednisolone injection); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have any of these health problems: A fungal infection or malaria infection in the brain.
- If you have a herpes infection of the eye.
- If you have nerve problems in the eye.
Injection (if given in the muscle):
- If you have idiopathic thrombocytopenic purpura (ITP).
This is not a list of all drugs or health problems that interact with Solu-Medrol (methylprednisolone injection).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Solu-Medrol (methylprednisolone injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Solu-Medrol?
- Tell all of your health care providers that you take Solu-Medrol (methylprednisolone injection). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Chickenpox and measles can be very bad or even deadly in some people taking steroid drugs like Solu-Medrol (methylprednisolone injection). Avoid being near anyone with chickenpox or measles if you have not had these health problems before. If you have been exposed to chickenpox or measles, talk with your doctor.
- This medicine lowers how much natural steroid your body makes. Tell your doctor if you have fever, infection, surgery, or injury. Your body's normal response to these stresses may be affected. You may need extra doses of steroid.
- Long-term use may raise the chance of cataracts or glaucoma. Talk with the doctor.
- This medicine may cause weak bones (osteoporosis) with long-term use. Talk with your doctor to see if you have a higher chance of weak bones or if you have any questions.
- Talk with your doctor before getting any vaccines. Use of some vaccines with Solu-Medrol (methylprednisolone injection) may either raise the chance of an infection or make the vaccine not work as well.
- If you have high blood sugar (diabetes), you will need to watch your blood sugar closely. Tell your doctor if you get signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Talk with your doctor before you drink alcohol.
- Liver problems have rarely happened with Solu-Medrol (methylprednisolone injection). Sometimes, this has been deadly. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Very bad health problems have happened when drugs like this one have been given into the spine (epidural). These include paralysis, loss of eyesight, stroke, and sometimes death. It is not known if drugs like this one are safe and effective when given into the spine. These drugs are not approved for this use. Talk with the doctor.
- Some products have benzyl alcohol. Do not give a product that has benzyl alcohol in it to a newborn or infant. Talk with the doctor to see if this product has benzyl alcohol in it.
- If you are 65 or older, use Solu-Medrol (methylprednisolone injection) with care. You could have more side effects.
- This medicine may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Solu-Medrol) best taken?
Use Solu-Medrol (methylprednisolone injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot.
- If you have been taking Solu-Medrol (methylprednisolone injection) for many weeks, talk with your doctor before stopping. You may want to slowly stop Solu-Medrol (methylprednisolone injection).
- Have your eye pressure checked if you are on Solu-Medrol (methylprednisolone injection) for a long time. Talk with your doctor.
- Have a bone density test as you have been told by your doctor. Talk with your doctor.
- You may need to lower how much salt is in your diet and take extra potassium. Talk with your doctor.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of Cushing's disease like weight gain in the upper back or belly, moon face, very bad headache, or slow healing.
- Signs of a weak adrenal gland like a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss.
- Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Feeling very tired, weak, or touchy; trembling; having a fast heartbeat, confusion, sweating, or dizziness if you missed a dose or recently stopped Solu-Medrol (methylprednisolone injection).
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Skin changes (pimples, stretch marks, slow healing, hair growth).
- Chest pain or pressure.
- Period (menstrual) changes.
- Bone or joint pain.
- Change in eyesight.
- Mental, mood, or behavior changes that are new or worse.
- A burning, numbness, or tingling feeling that is not normal.
- Any unexplained bruising or bleeding.
- Very bad belly pain.
- Black, tarry, or bloody stools.
- Throwing up blood or throw up that looks like coffee grounds.
What are some other side effects of Solu-Medrol?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Trouble sleeping.
- Sweating a lot.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Solu-Medrol?
- If you need to store Solu-Medrol (methylprednisolone injection) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Solu-Medrol (methylprednisolone injection), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
- Methylprednisolone vs Prednisone - How do they compare?
- Does methylprednisolone help with COVID?
- How long does methylprednisolone tablets stay in your system?
- Methylprednisolone Tablets - How long does a Medrol pack tablet stay in your system?
- How and where are steroid injections given?
- Why is Yonsa taken with methylprednisolone?
More about Solu-Medrol (methylprednisolone)
- Check interactions
- Pricing & coupons
- Reviews (15)
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Drug class: glucocorticoids
- En español
Medrol, Medrol Dosepak, Depo-Medrol, MethylPREDNISolone Dose Pack, ... +2 more
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.