Does methylprednisolone help with COVID?
Methylprednisolone can help with COVID according to a 2022 systematic review of 33 studies that reported the use of methylprednisolone was associated with:
- Fewer deaths in the short-term (relative risk [RR] 0.73 which means patients given methylprednisolone were 0.73 times less likely to die within 28 days than those not given methylprednisolone)
- A decrease in the likelihood of being admitted to ICU (RR 0.77)
- A decrease in the need for mechanical ventilation (RR 0.69)
- More ventilator-free days within 28 days (mean difference [MD] 2.81)
- No significant increase in the risk of secondary infections (RR 1.04).
Use of higher dose methylprednisolone was associated with a possible prolongation in the duration of viral shedding, but this was not seen with lower dose methylprednisolone (≤ 2 mg/kg/day for ≤7 days).
References
- Hong, S., Wang, H., Zhang, Z., & Qiao, L. (2022). The roles of methylprednisolone treatment in patients with COVID-19: A systematic review and meta-analysis. Steroids, 183, 109022. https://doi.org/10.1016/j.steroids.2022.109022
Read next
Related medical questions
- Methylprednisolone vs Prednisone - How do they compare?
- How long does methylprednisolone tablets stay in your system?
- Methylprednisolone Tablets - How long does a Medrol pack tablet stay in your system?
- Which breathing techniques help with COVID-19?
- Is Omicron worse than Delta?
- How effective is Lagevrio (molnupiravir) for COVID-19?
- Can you become immune to COVID-19?
- Is obesity a major risk factor for Covid-19?
- COVID-19: Why is social distancing so important?
- COVID-19 vaccines and variants: What you should know
- Should I wear a face mask to protect myself from COVID-19?
- Why do more men die from coronavirus?
- Can Ivermectin be used to treat COVID-19?
- Can you take Ibuprofen if you have COVID-19 (coronavirus)?
- What antibiotics kill Covid-19 (coronavirus)?
- COVID-19: What are the Stages and Causes of Death?
- What's the difference between Bacteria and Viruses?
- Does Zinc protect you from Covid-19 or boost your immune system?
- Does Losartan block the receptor used by the Coronavirus?
- An Update: Is hydroxychloroquine effective for COVID-19?
- How do I Treat Nasal Congestion with COVID-19?
- Where can I buy an at-home test kit for COVID-19 (coronavirus)?
- Does Mucinex help with Covid?
- Can you take Paxlovid twice if COVID rebounds?
- Does Tamiflu (oseltamivir) work on COVID-19?
- Can vitamin C prevent or treat COVID-19 (coronavirus)?
- Should I take Paxlovid after a Positive COVID-19 Test?
- How long does COVID-19 last? and other COVID-19 FAQ
- Can I take NyQuil with COVID or after the COVID vaccine?
- How effective is Paxlovid for COVID-19?
Drug information
- Methylprednisolone Information for Consumers
- Methylprednisolone prescribing info & package insert (for Health Professionals)
- Side Effects of Methylprednisolone (detailed)
Related support groups
- Methylprednisolone (77 questions, 148 members)
- COVID-19 (103 questions, 87 members)