Rabeprazole delayed-release tabletsPronunciation
Generic Name: rabeprazole (ra-BEP-ra-zole)
Brand Name: Aciphex
Rabeprazole delayed-release tablets are used for:
Healing and maintaining healing of irritation of the esophagus. It is also used to treat symptoms of gastroesophageal reflux disease (GERD) (eg, heartburn). It may be used for short-term treatment of ulcers of the small intestine. It may be used with certain antibiotics to treat ulcers of the small intestine and to help prevent them from coming back. It may be used to treat conditions that cause your body to make too much stomach acid (eg, Zollinger-Ellison syndrome). It may also be used for other conditions as determined by your doctor.
Rabeprazole delayed-release tablets are a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.
Do NOT use rabeprazole delayed-release tablets if:
- you are allergic to any ingredient in rabeprazole delayed-release tablets or to similar medicines (eg, omeprazole)
- you are taking atazanavir, dasatinib, erlotinib, or rilpivirine
Contact your doctor or health care provider right away if any of these apply to you.
Before using rabeprazole delayed-release tablets:
Some medical conditions may interact with rabeprazole delayed-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have low blood magnesium levels, low blood vitamin B12 levels or vitamin B12 deficiency, liver problems, or stomach or bowel cancer
- if you have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (eg, smoking, poor nutrition)
Some MEDICINES MAY INTERACT with rabeprazole delayed-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased
- Anticoagulants (eg, warfarin), cyclosporine, diazepam, digoxin, methotrexate, phenytoin, saquinavir, or theophylline because the risk of their side effects may be increased by rabeprazole delayed-release tablets
- Atazanavir, bosutinib, dasatinib, erlotinib, indinavir, itraconazole, ketoconazole, mycophenolate, nelfinavir, nilotinib, posaconazole, or rilpivirine because their effectiveness may be decreased by rabeprazole delayed-release tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if rabeprazole delayed-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use rabeprazole delayed-release tablets:
Use rabeprazole delayed-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Rabeprazole delayed-release tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get rabeprazole delayed-release tablets refilled.
- Take rabeprazole delayed-release tablets by mouth with or without food.
- Swallow rabeprazole delayed-release tablets whole. Do not break, crush, or chew before swallowing.
- Tell your doctor if you cannot swallow tablets whole. You may need a different medicine.
- You may take antacids while you are taking rabeprazole delayed-release tablets if you are directed to do so by your doctor.
- Continue to take rabeprazole delayed-release tablets even if you feel well. Do not miss any doses.
- If you miss a dose of rabeprazole delayed-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use rabeprazole delayed-release tablets.
Important safety information:
- Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
- Do NOT change your dose, stop taking rabeprazole delayed-release tablets, or take rabeprazole delayed-release tablets for longer than prescribed without checking with your doctor.
- Rabeprazole delayed-release tablets may increase the risk of a serious form of diarrhea. Contact your doctor right away if stomach pain or cramps, severe or persistent diarrhea or fever, or bloody or watery stools occur. Discuss any questions or concerns with your doctor.
- Rabeprazole delayed-release tablets may increase the risk of hip, wrist, and spine fractures in patients with weak bones (osteoporosis). The risk may be greater if you use rabeprazole delayed-release tablets in high doses, for long periods of time, or if you are older than 50 years old. Contact your doctor if you have any questions about this information.
- Low blood magnesium levels have been reported rarely in patients taking proton pump inhibitors for at least 3 months. In most cases, this effect was seen after a year of treatment. If you will be taking rabeprazole delayed-release tablets for a long time, or if you take certain other medicines (eg, digoxin, diuretics), your doctor may perform lab tests to check for low blood magnesium levels. Seek medical attention right away if you experience symptoms of low blood magnesium levels (eg, dizziness; fast or irregular heartbeat; involuntary muscle movements; jitteriness or tremors; muscle aches, cramps, pain, spasms, or weakness; seizures).
- Long-term treatment (eg, longer than 3 years) with medicines like this one has rarely caused low vitamin B12 levels. Discuss any questions or concerns with your doctor.
- Check with your doctor to see whether you should take a calcium and vitamin D supplement while you use rabeprazole delayed-release tablets.
- Tell your doctor or dentist that you take rabeprazole delayed-release tablets before you receive any medical or dental care, emergency care, or surgery.
- Use rabeprazole delayed-release tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially hip, wrist, and spine fractures.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using rabeprazole delayed-release tablets while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use rabeprazole delayed-release tablets, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of rabeprazole delayed-release tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; gas; headache; mild diarrhea or stomach pain; mild sore throat.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody or watery stools; bone pain; chest pain; dizziness; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; involuntary muscle movements; joint or muscle aches or pain; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea, nausea, or vomiting; severe or persistent stomach or back pain; stomach cramps; swelling of the hands, ankles, or feet; symptoms of kidney problems (eg, not able to pass urine, change in the amount of urine produced, blood in the urine, a big weight gain); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, unusual nausea, yellowing of the skin or eyes); tremors; unexplained weight loss; unusual bruising or bleeding; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Store rabeprazole delayed-release tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep rabeprazole delayed-release tablets out of the reach of children and away from pets.
- If you have any questions about rabeprazole delayed-release tablets, please talk with your doctor, pharmacist, or other health care provider.
- Rabeprazole delayed-release tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take rabeprazole delayed-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about rabeprazole delayed-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to rabeprazole delayed-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using rabeprazole delayed-release tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: proton pump inhibitors