Generic name: Mesalamine Suppositories [ me-SAL-a-meen ]
Brand name: Canasa
Drug class: 5-aminosalicylates
Medically reviewed by Drugs.com. Last updated on Feb 19, 2023.
Uses of Mesalamine Suppositories:
- It is used to treat mild to moderate disease at the far end of the colon.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Mesalamine Suppositories?
- If you have an allergy to mesalamine, salicylates, sulfasalazine, or any other part of this medicine (mesalamine suppositories).
- If you are allergic to this medicine (mesalamine suppositories); any part of this medicine (mesalamine suppositories); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (mesalamine suppositories) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Mesalamine Suppositories?
- Tell all of your health care providers that you take this medicine (mesalamine suppositories). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine (mesalamine suppositories).
- If you are 65 or older, use this medicine (mesalamine suppositories) with care. You could have more side effects.
- Do not give to children and teenagers who have or are getting better from flu signs, chickenpox, or other viral infections due to the chance of Reye's syndrome. Reye's syndrome causes very bad problems to the brain and liver.
- This medicine may stain fabric, flooring, painted surfaces, marble, granite, vinyl, and enamel.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Mesalamine Suppositories) best taken?
Use this medicine (mesalamine suppositories) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- You could be on both a tablet or capsule and a rectal product at the same time.
- Keep using this medicine (mesalamine suppositories) as you have been told by your doctor or other health care provider, even if you feel well.
- Use suppository rectally.
- Use at bedtime.
- Wash your hands before and after use.
- If suppository is soft, chill in a refrigerator or run cold water over it.
- Take foil off the suppository and put in, pointed end first. Do not handle too much. Keep the suppository in for 1 to 3 hours or longer if you can. Do not cut or break the suppository.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Chest pain or pressure.
- Fast or abnormal heartbeat.
- Fever, chills, or sore throat; any unexplained bruising or bleeding; or feeling very tired or weak.
- Some people may have a reaction to this medicine (mesalamine suppositories) that looks like the signs of ulcerative colitis. Call your doctor right away if you have very bad belly pain or cramps, bloody stools, fever, headache, or rash.
- Liver problems have rarely happened with this medicine (mesalamine suppositories). Sometimes, this has been deadly. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Some heart problems have rarely happened with this medicine (mesalamine suppositories). Sometimes, this has been deadly. Call your doctor right away if you have shortness of breath, a big weight gain, or swelling in the arms or legs.
What are some other side effects of Mesalamine Suppositories?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stomach pain or diarrhea.
- Upset stomach or throwing up.
- Nose or throat irritation.
- Back pain.
- Rectal irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Mesalamine Suppositories?
- Store at room temperature or in a refrigerator. Do not freeze.
- Protect from heat and light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (mesalamine suppositories), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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