Generic Name: anakinra (an-a-KIN-ra)
Brand Name: Kineret
Kineret is used for:
Reducing moderately to severely active rheumatoid arthritis in patients 18 years old and older who have not successfully responded to other medicines. It is also used to treat neonatal-onset multisystem inflammatory disease (NOMID). It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.
Kineret is an interleukin-1 (IL-1) blocker. It works by blocking the activity of interleukin-1 by binding to its receptor, which reduces inflammation and other signs and symptoms of arthritis.
Do NOT use Kineret if:
- you are allergic to any ingredient in Kineret
- you are allergic to proteins derived from Escherichia coli (E. coli)
- you are using a tumor necrosis factor (TNF)-blocking agent (eg, adalimumab)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Kineret:
Some medical conditions may interact with Kineret. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances, including rubber or latex
- if you have kidney problems
- if you have an infection, a history of serious infection or infection that keeps coming back, a weakened immune system, low white blood cell counts, low blood platelet levels, or tuberculosis (TB), or you have had a positive TB skin test
- if you are planning to receive a vaccine
Some MEDICINES MAY INTERACT with Kineret. Tell your health care provider if you are taking any other medicines, especially any of the following:
- TNF-blocking agents (eg, adalimumab) because the risk of severe infection and/or low white blood cell counts may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Kineret may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Kineret:
Use Kineret as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Kineret. It also comes with detailed instructions for use. Read them carefully. Read them again each time you get Kineret refilled. Ask your doctor, nurse, or pharmacist any questions that you may have about this information.
- Kineret may be administered as an injection at your doctor's office, hospital, or clinic. If you are using Kineret at home, carefully follow the injection procedures taught to you by your health care provider. Ask your doctor or other health care provider if you have any questions about how to administer Kineret.
- Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle or a vein.
- Rotate injection sites. Do not inject Kineret into an area that is irritated, bruised, red, infected, scarred, or has stretch marks.
- Kineret should be administered at the same time each day.
- Wash your hands thoroughly with soap and warm water before using Kineret.
- Before using Kineret, take it out of the refrigerator and leave it at room temperature for 30 minutes.
- Use a new syringe every day. Use the prefilled syringe only once. Throw away any unused portion of the medicine. Do not save for future use.
- If Kineret contains particles or is discolored, or if the container is cracked or damaged in any way, do not use it.
- Do not use a syringe that has been dropped or broken. Properly dispose of the damaged syringe and replace it with the syringe that would be used on the last day of the week in your current box. For example, if you start on Wednesday, the last day of the week in your series is Tuesday. After using all of the remaining syringes in your current box, start your next box.
- Do not use Kineret beyond the expiration date on the container.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
- If you miss a dose of Kineret, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses on the same day.
Ask your health care provider any questions you may have about how to use Kineret.
Important safety information:
- Anakinra may put your body at an increased risk for serious infections. This drug is not recommended if you have an infection or an infection-related illness (eg, pneumonia, tuberculosis). Tell your doctor if you have, or if you develop, any symptoms of an infection, such as fever, persistent sore throat, productive cough (eg, sputum-producing), or unusual weakness. The risk of developing serious infections is even greater if you are also using a TNF medicine, such as etanercept.
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Kineret.
- Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking Kineret. Check with your doctor before having any vaccinations while you are using Kineret.
- LAB TESTS, including white blood cell counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Kineret during pregnancy. It is unknown if Kineret is excreted in breast milk. If you are or will be breast-feeding while you are using Kineret, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of Kineret:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; flu-like symptoms; headache; nausea; reaction at the injection site (eg, bruising, itching, pain, redness, stinging, swelling); runny nose; sinus inflammation; sore throat; stomach pain; upper respiratory tract infection; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); fainting; fast heartbeat; swelling; symptoms of infection (fever, chills, or persistent cough or sore throat; increased or painful urination; open sores on your body; warm, red, or swollen skin); unexplained bone or joint pain; unusual bruising or bleeding; unusual sweating; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Kineret:
Store unopened syringes of Kineret in the refrigerator, between 36 and 46 degrees F (2 to 8 degrees C). Do not shake or freeze. Do not use a syringe that has been left at room temperature for more than 24 hours. Do not use after the expiration date. Do not store in the bathroom. Keep Kineret out of the reach of children and away from pets.
- If you have any questions about Kineret, please talk with your doctor, pharmacist, or other health care provider.
- Kineret is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Kineret or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Kineret. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Kineret. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Kineret.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Kineret (anakinra)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 5 Reviews – Add your own review/rating
- Drug class: antirheumatics