Robaxin-750 Side Effects

Generic name: methocarbamol

Medically reviewed by Drugs.com. Last updated on Mar 5, 2025.

Note: This document provides detailed information about Robaxin-750 Side Effects associated with methocarbamol. Some dosage forms listed on this page may not apply specifically to the brand name Robaxin-750.

Applies to methocarbamol: oral tablet.

Other dosage forms:

• injection solution

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). The use of alcohol or other medicines that affect the CNS with risperidone may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics.

This medicine may cause some people to become dizzy or drowsy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests. .

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines) and herbal or vitamin supplements.

Serious side effects of Robaxin-750

Along with its needed effects, methocarbamol (the active ingredient contained in Robaxin-750) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking methocarbamol:

Get emergency help immediately if any of the following symptoms of overdose occur while taking methocarbamol:

Symptoms of Overdose

• loss of consciousness
• shaking or jerking of one area or side of the body

Other side effects of Robaxin-750

Some side effects of methocarbamol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to methocarbamol: injectable solution, oral tablet.

General adverse events

The most commonly reported adverse reaction is headache.^[Ref]

Cardiovascular

• Frequency not reported: Syncope, hypotension, bradycardia, thrombophlebitis^[Ref]

Some cardiovascular events may have been due to an overly rapid IV injection.

Most syncope cases resulted in spontaneous recovery; however, epinephrine, injectable steroids, and/or injectable antihistamines have been used in some cases.^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylaxis

Nervous system

• Frequency not reported: Dizziness, lightheadedness, headache, drowsiness, mild muscular incoordination, metallic taste, nystagmus, sedation, seizures (including grand mal), tremor^[Ref]

Convulsions have been reported with IV administration in patients with seizure disorders.^[Ref]

Psychiatric

• Frequency not reported: Amnesia, confusion, insomnia, restlessness, anxiety

Local

• Frequency not reported: Pain and sloughing at the injection site

Dermatologic

• Frequency not reported: Urticaria, pruritus, rash, angioneurotic edema^[Ref]

Gastrointestinal

• Frequency not reported: Dyspepsia, nausea, vomiting, anorexia^[Ref]

Other

• Frequency not reported: Vertigo, fever^[Ref]

Ocular

• Frequency not reported: Blurred vision, conjunctivitis, diplopia^[Ref]

Hematologic

• Frequency not reported: Leukopenia^[Ref]

Hepatic

• Frequency not reported: Jaundice (including cholestatic jaundice)

Respiratory

• Frequency not reported: Nasal congestion, bronchospasm^[Ref]

See also:

Frequently asked questions

• What is Ardosons called in the U.S?
• What is Miderizone used for?
• What is the maximum dose of methocarbamol?

Further information

Robaxin-750 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer