Robaxin-750 Side Effects
Generic name: methocarbamol
Medically reviewed by Drugs.com. Last updated on Jan 18, 2024.
Note: This document contains side effect information about methocarbamol. Some dosage forms listed on this page may not apply to the brand name Robaxin-750.
Applies to methocarbamol: injection solution. Other dosage forms:
Serious side effects of Robaxin-750
Along with its needed effects, methocarbamol (the active ingredient contained in Robaxin-750) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking methocarbamol:
Incidence not known
- Black, tarry stools
- blurred vision
- changes in skin color
- chest pain or discomfort
- chills
- clay-colored stools
- confusion
- convulsions
- cough
- dark urine
- difficulty swallowing
- dizziness, faintness, or lightheadedness when suddenly getting up from a lying or sitting position
- drowsiness
- fast heartbeat
- fever
- headache
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- lightheadedness, dizziness, or fainting
- loss of appetite
- loss of bladder control
- loss or problems with memory
- muscle spasm or jerking of all extremities
- nausea
- pain, tenderness, or swelling of the foot or leg
- painful or difficult urination
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rash, hives, itching, red skin
- slow or irregular heartbeat
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- stomach pain
- sudden loss of consciousness
- sweating
- swollen glands
- tightness in the chest
- unpleasant breath odor
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood
- yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking methocarbamol:
Symptoms of overdose
- Loss of consciousness
- shaking or jerking of one area or side of the body
Other side effects of Robaxin-750
Some side effects of methocarbamol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Belching
- bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- burning, dry, or itching eyes
- discharge, excessive tearing
- double vision
- feeling of constant movement of self or surroundings
- feeling of warmth
- heartburn
- indigestion
- metallic taste
- redness of the face, neck, arms, and occasionally, upper chest
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
- sensation of spinning
- stuffy nose
- trouble sleeping
- uncontrolled eye movements
- vomiting
For Healthcare Professionals
Applies to methocarbamol: injectable solution, oral tablet.
General
The most commonly reported adverse reaction is headache.[Ref]
Cardiovascular
Frequency not reported: Syncope, hypotension, bradycardia, thrombophlebitis[Ref]
Some cardiovascular events may have been due to an overly rapid IV injection.
Most syncope cases resulted in spontaneous recovery; however, epinephrine, injectable steroids, and/or injectable antihistamines have been used in some cases.[Ref]
Hypersensitivity
Frequency not reported: Anaphylaxis
Nervous system
Frequency not reported: Dizziness, lightheadedness, headache, drowsiness, mild muscular incoordination, metallic taste, nystagmus, sedation, seizures (including grand mal), tremor[Ref]
Convulsions have been reported with IV administration in patients with seizure disorders.[Ref]
Psychiatric
Frequency not reported: Amnesia, confusion, insomnia, restlessness, anxiety
Local
Frequency not reported: Pain and sloughing at the injection site
Dermatologic
Frequency not reported: Urticaria, pruritus, rash, angioneurotic edema[Ref]
Gastrointestinal
Frequency not reported: Dyspepsia, nausea, vomiting, anorexia[Ref]
Other
Frequency not reported: Vertigo, fever[Ref]
Ocular
Frequency not reported: Blurred vision, conjunctivitis, diplopia[Ref]
Hematologic
Frequency not reported: Leukopenia[Ref]
Hepatic
Frequency not reported: Jaundice (including cholestatic jaundice)
Respiratory
Frequency not reported: Nasal congestion, bronchospasm[Ref]
Frequently asked questions
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More about Robaxin-750 (methocarbamol)
- Check interactions
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- Reviews (42)
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- Latest FDA alerts (7)
- Side effects
- Dosage information
- During pregnancy
- Drug class: skeletal muscle relaxants
Patient resources
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Other formulations
Related treatment guides
References
1. Product Information. Robaxin (methocarbamol). Whitehall-Robbins. PROD.
2. Multum Information Services, Inc. Expert Review Panel
3. CAMPBELL DJ, SHERBANIUK R, RIGBY J. FALSE POSITIVE REACTION DUE TO METHOCARBAMOL IN THE SCREENING TEST FOR VANILMANDELIC ACID (VMA). CLIN CHEM. 1964;10:447-50.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.