Ontralfy Side Effects

This medicine may cause dizziness, drowsiness, lightheadedness, clumsiness or unsteadiness, or vision problems in some people. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, and able to see well.

Hallucinations (visual) may occur while you are using this medicine. Check with your doctor right away if you have hallucinations (seeing things that are not there).

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Do not suddenly Stop taking tizanidine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping completely. This may help prevent a possible worsening of your condition and reduce the possibility of withdrawal symptoms.

Tizanidine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Serious side effects of Ontralfy

Along with its needed effects, tizanidine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tizanidine:

Get emergency help immediately if any of the following symptoms of overdose occur while taking tizanidine:

Symptoms of overdose

• blurred vision
• change in consciousness
• chest pain or discomfort
• confusion
• decreased awareness or responsiveness
• difficult or troubled breathing
• dizziness, faintness or lightheadedness when getting up from a lying position
• irregular, fast or slow, or shallow breathing
• lightheadedness, dizziness, or fainting
• loss of consciousness
• pale or blue lips, fingernails, or skin
• severe sleepiness
• sleepiness or unusual drowsiness
• slow or irregular heartbeat
• sweating
• unusual tiredness or weakness

Other side effects of Ontralfy

Some side effects of tizanidine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to tizanidine: oral capsule, oral tablet.

General adverse events

The most frequently reported adverse reactions include dry mouth, somnolence/sedation, asthenia, and dizziness.^[Ref]

Nervous system

• Very common (10% or more): Somnolence (up to 48%), dizziness (up to 16%)
• Common (1% to 10%): Speech disorder, dyskinesia
• Frequency not reported: Headache, ataxia, dysarthria
• Postmarketing reports: Convulsion, paresthesia, tremor^[Ref]

Gastrointestinal

• Very common (10% or more): Dry mouth (up to 49%)
• Common (1% to 10%): Vomiting, constipation
• Rare (0.01% to 0.1%): Nausea, gastrointestinal disorder
• Frequency not reported: Abdominal pain, loss of appetite^[Ref]

Hepatic

• Common (1% to 10%): Liver test abnormality
• Very rare (less than 0.01%): Hepatic failure
• Frequency not reported: Hepatotoxicity
• Postmarketing reports: Hepatitis^[Ref]

Cardiovascular

• Common (1% to 10%): Bradycardia, hypotension, tachycardia
• Postmarketing reports: Syncope, ventricular tachycardia, QT prolongation^[Ref]

Ocular

• Common (1% to 10%): Amblyopia
• Frequency not reported: Accommodation disorder^[Ref]

Dermatologic

• Frequency not reported: Pruritus
• Postmarketing reports: Stevens Johnson Syndrome, exfoliative dermatitis, rash^[Ref]

Other

• Common (1% to 10%): Fatigue
• Frequency not reported: Drug withdrawal reactions including rebound hypertension, tachycardia, and hypertonia^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection, urinary frequency^[Ref]

Respiratory

• Common (1% to 10%): Pharyngitis, rhinitis^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylaxis, hypersensitivity reactions
• Postmarketing reports: Anaphylactic Reaction^[Ref]

Immunologic

• Common (1% to 10%): Infection, flu syndrome^[Ref]

Musculoskeletal

• Rare (0.01% to 0.1%): Muscular weakness
• Postmarketing reports: Arthralgia^[Ref]

Psychiatric

• Common (1% to 10%): Nervousness
• Rare (0.01% to 0.1%): Hallucinations, insomnia, sleep disorders
• Frequency not reported: Confusional state
• Postmarketing reports: Depression^[Ref]

See also:

Frequently asked questions

• What is Miderizone used for?

Further information

Ontralfy side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer