Moban Side Effects

Generic name: molindone

Note: This document contains side effect information about molindone. Some dosage forms listed on this page may not apply to the brand name Moban.

Applies to molindone: oral syrup, oral tablet.

Serious side effects of Moban

Along with its needed effects, molindone (the active ingredient contained in Moban) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking molindone:

More common

• Difficulty with talking or swallowing
• inability to move the eyes
• lip smacking or puckering
• loss of balance control
• mask-like face
• muscle spasms, especially of the neck and back
• puffing of the cheeks
• rapid or worm-like movements of the tongue
• restlessness or need to keep moving (severe)
• shuffling walk
• stiffness of the arms and legs
• trembling and shaking of the hands
• twisting movements of the body
• uncontrolled movements of the arms and legs
• unusual chewing movements

Less common

• Discouragement
• false or unusual sense of well-being
• feeling sad or empty
• irritability
• lack of appetite
• loss of interest or pleasure
• tiredness
• trouble sitting still
• trouble with concentrating
• trouble with sleeping

Rare

• Blurred vision
• confusion
• dark-colored urine
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• general feeling of tiredness or weakness
• headache
• hot, dry skin, or lack of sweating
• light-colored stools
• muscle weakness
• skin rash
• stomach pain, continuing
• sweating
• unusual tiredness or weakness
• vomiting
• yellow eyes or skin

Incidence not known

• Absence of or decrease in body movement
• decrease in frequency of urination
• decrease in urine volume
• difficulty in passing urine (dribbling)
• fast, pounding, or irregular heartbeat or pulse
• increased blinking or spasms of the eyelid
• painful urination
• slowed movements
• sticking out of the tongue
• tic-like (jerky) movements of the head, face, mouth, and neck
• trouble with breathing, speaking, or swallowing
• twisting movements of the neck, trunk, arms, or legs
• unusual facial expressions

Other side effects of Moban

Some side effects of molindone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Constipation
• decreased sweating
• difficult urination
• drowsiness
• dryness of the mouth
• headache
• nausea
• stuffy nose

Less common

• Absent, missed, or irregular menstrual periods
• changes in menstrual periods
• decreased sexual ability
• false sense of well-being
• stopping of menstrual bleeding
• swelling of the breasts or breast soreness in both females and males
• unexpected or excess milk flow from breasts
• unusual secretion of milk

Incidence not known

• Decreased interest in sexual intercourse
• inability to have or keep an erection
• increased in sexual ability, desire, drive, or performance
• increased interest in sexual intercourse
• loss in sexual ability, desire, drive, or performance
• painful or prolonged erection of the penis
• weight gain or loss

For Healthcare Professionals

Applies to molindone: oral concentrate, oral tablet.

General

The most common side effects include drowsiness; less frequently occurring side effects include depression, hyperactivity, and euphoria.^[Ref]

Nervous system

Akathisia/motor restlessness occurred early in treatment.

Drowsiness occurred with initial treatment and usually subsided with continued use or lowering of the dose.

Extrapyramidal symptoms (EPS) may occur in susceptible patients, but is usually reversible with appropriate therapy; EPS symptoms include akathisia.

Parkinson syndrome occurred less frequently than akathisia and includes rigidity, immobility, and reduction of voluntary movements/tremor.^[Ref]

Frequency not reported: Drowsiness, hyperactivity, extrapyramidal symptoms, akathisia/motor restlessness, dystonia, tardive dyskinesia, Parkinson syndrome^[Ref]

Genitourinary

Frequency not reported: Urinary retention, priapism, amenorrhea, resumption of menses, heavy menses, galactorrhea^[Ref]

Urinary retention may occur more frequently during concomitant use with anticholinergic drugs.^[Ref]

Gastrointestinal

Frequency not reported: Dry mouth, nausea, salivation, constipation^[Ref]

Constipation may occur more frequently during concomitant use with anticholinergic drugs.^[Ref]

Cardiovascular

Rare, transient, nonspecific T wave changes have been reported on ECGs; however, there is no established association with this drug.^[Ref]

Frequency not reported: Tachycardia, T wave changes, significant hypotension^[Ref]

Hematologic

Frequency not reported: Leukopenia, leukocytosis, alterations in red blood cells^[Ref]

Red blood cell alterations were not clinically significant.^[Ref]

Psychiatric

Frequency not reported: Depression, euphoria, increased libido^[Ref]

Metabolic

Frequency not reported: Blood glucose alteration, weight gain/loss (not excessive)^[Ref]

Blood glucose alterations were not considered clinically significant.^[Ref]

Endocrine

Thyroid function alterations were not clinically significant.^[Ref]

Frequency not reported: Alterations in thyroid function, gynecomastia^[Ref]

Dermatologic

Nonspecific skin rash (likely of allergic origin) occurred early during treatment.

Skin pigmentation did not occur when this drug is used alone.^[Ref]

Frequency not reported: Skin rash, skin pigmentation^[Ref]

Hepatic

Frequency not reported: Alterations in liver function^[Ref]

Liver function alterations have been clinically significant in some patients.^[Ref]

Renal

Frequency not reported: Alterations in blood urea nitrogen (BUN)^[Ref]

BUN alterations were not clinically significant.^[Ref]

Ocular

Frequency not reported: Blurring of vision^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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