Molindone use while Breastfeeding
Drugs containing Molindone: Moban
Medically reviewed by Drugs.com. Last updated on Aug 19, 2018.
Molindone Levels and Effects while Breastfeeding
Summary of Use during Lactation
Because there is no published experience with molindone during breastfeeding, other antipsychotic agents are preferred.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Galactorrhea has been reported with molindone. Hyperprolactinemia appears to be the cause of the galactorrhea. The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway. The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs to Consider
1. Wesp CE Jr, Annitto W, Feinsod R. Galactorrhea associated with molindone. Am J Psychiatry. 1979;136:975. PMID: 572143
2. Kahn JL. More on galactorrhea associated with molindone. Am J Psychiatry. 1979;136:1617-8. Letter. PMID: 574364
3. Turkington RW. Prolactin secretion in patients treated with various drugs: phenothiazines, tricyclic antidepressants, reserpine, and methyldopa. Arch Intern Med. 1972;130:349-54. PMID: 4560178
4. Turkington RW. Serum prolactin levels in patients with gynecomastia. J Clin Endocrinol Metab. 1972;34:62-6. PMID: 5061776
5. Meltzer HY, Fang VS. The effect of neuroleptics on serum prolactin in schizophrenic patients. Arch Gen Psychiatry. 1976;33:279-86. PMID: 1259521
6. Maguire GA. Prolactin elevation with antipsychotic medications: mechanisms of action and clinical consequences. J Clin Psychiatry. 2002;63(suppl 4):56-62. PMID: 11913677
CAS Registry Number
LactMed Record Number
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More about molindone
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- Drug class: miscellaneous antipsychotic agents
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