Molindone Side Effects
Applies to molindone: oral concentrate, oral tablet
The most common side effects include drowsiness; less frequently occurring side effects include depression, hyperactivity, and euphoria.[Ref]
Akathisia/motor restlessness occurred early in treatment.
Drowsiness occurred with initial treatment and usually subsided with continued use or lowering of the dose.
Extrapyramidal symptoms (EPS) may occur in susceptible patients, but is usually reversible with appropriate therapy; EPS symptoms include akathisia.
Parkinson syndrome occurred less frequently than akathisia and includes rigidity, immobility, and reduction of voluntary movements/tremor.[Ref]
Frequency not reported: Drowsiness, hyperactivity, extrapyramidal symptoms, akathisia/motor restlessness, dystonia, tardive dyskinesia, Parkinson syndrome[Ref]
Urinary retention may occur more frequently during concomitant use with anticholinergic drugs.[Ref]
Frequency not reported: Urinary retention, priapism, amenorrhea, resumption of menses, heavy menses, galactorrhea[Ref]
Frequency not reported: Dry mouth, nausea, salivation, constipation[Ref]
Constipation may occur more frequently during concomitant use with anticholinergic drugs.[Ref]
Frequency not reported: Tachycardia, T wave changes, significant hypotension[Ref]
Rare, transient, nonspecific T wave changes have been reported on ECGs; however, there is no established association with this drug.[Ref]
Red blood cell alterations were not clinically significant.[Ref]
Frequency not reported: Leukopenia, leukocytosis, alterations in red blood cells[Ref]
Frequency not reported: Depression, euphoria, increased libido[Ref]
Blood glucose alterations were not considered clinically significant.[Ref]
Frequency not reported: Blood glucose alteration, weight gain/loss (not excessive)[Ref]
Thyroid function alterations were not clinically significant.[Ref]
Frequency not reported: Alterations in thyroid function, gynecomastia[Ref]
Nonspecific skin rash (likely of allergic origin) occurred early during treatment.
Skin pigmentation did not occur when this drug is used alone.[Ref]
Frequency not reported: Skin rash, skin pigmentation[Ref]
Frequency not reported: Alterations in liver function[Ref]
Liver function alterations have been clinically significant in some patients.[Ref]
Frequency not reported: Alterations in blood urea nitrogen (BUN)[Ref]
BUN alterations were not clinically significant.[Ref]
Frequency not reported: Blurring of vision[Ref]
1. "Product Information. Moban (molindone)." Gate Pharmaceuticals, Sellersville, PA.
Not all side effects for molindone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about molindone
- Other brands: Moban
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