Meclofenamate Side Effects
Commonly reported side effects of meclofenamate include: behavioral changes, diarrhea, and nausea. Other side effects include: abdominal distention, abdominal pain, dizziness, dyspepsia, headache, nausea and vomiting, and skin rash. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to meclofenamate: oral capsules
Side effects include:
Diarrhea, nausea with or without vomiting, other GI disorders, abdominal pain, flatulence, pyrosis, dizziness, headache, rash.
For Healthcare Professionals
Applies to meclofenamate: compounding powder, oral capsule
The most frequently reported side effects were gastrointestinal in nature and included diarrhea, nausea with or without vomiting, and abdominal pain.[Ref]
Very common (10% or more): Diarrhea (up to 33%), nausea (11%)
Common (1% to 10%): Vomiting, abdominal pain, pyrosis, flatulence, constipation, stomatitis, peptic ulcer
Frequency not reported: Colitis, bleeding, perforation, ulcer, paralytic ileus[Ref]
Common (1% to 10%): Rash, urticaria, pruritus
Frequency not reported: Erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, erythema nodosum, hair loss[Ref]
Common (1% to 10%): Headache, dizziness
Frequency not reported: Paresthesia, taste disturbance[Ref]
Common (1% to 10%): Edema, tinnitus
Frequency not reported: Malaise, fatigue[Ref]
Frequency not reported: Palpitations[Ref]
Frequency not reported: Neutropenia, thrombocytopenic purpura, leukopenia, agranulocytosis, hemolytic anemia, eosinophilia, hemoglobin decreased, hematocrit decreased[Ref]
Frequency not reported: Liver function tests abnormal, cholestatic jaundice[Ref]
Frequency not reported: Renal failure[Ref]
Common (1% to 10%): Anorexia[Ref]
Frequency not reported: Vision blurred, visual acuity decreased, temporary vision loss, reversible color vision loss, macular fibrosis, macular edema, perimacular edema, conjunctivitis, iritis[Ref]
Frequency not reported: Depression, insomnia[Ref]
Frequency not reported: Nocturia[Ref]
Frequency not reported: Lupus-like syndrome[Ref]
Frequency not reported: Serum sickness-like syndrome
1. "Product Information. Meclofenamate Sodium (meclofenamate)." Mylan Pharmaceuticals Inc, Morgantown, WV.
Not all side effects for meclofenamate may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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