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Meclofenamate Side Effects

For the Consumer

Applies to meclofenamate: oral capsules

Side effects include:

Diarrhea, nausea with or without vomiting, other GI disorders, abdominal pain, flatulence, pyrosis, dizziness, headache, rash.

For Healthcare Professionals

Applies to meclofenamate: compounding powder, oral capsule

General

The most frequently reported side effects were gastrointestinal in nature and included diarrhea, nausea with or without vomiting, and abdominal pain.[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (up to 33%), nausea (11%)
Common (1% to 10%): Vomiting, abdominal pain, pyrosis, flatulence, constipation, stomatitis, peptic ulcer
Frequency not reported: Colitis, bleeding, perforation, ulcer, paralytic ileus[Ref]

Dermatologic

Common (1% to 10%): Rash, urticaria, pruritus
Frequency not reported: Erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, erythema nodosum, hair loss[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness
Frequency not reported: Paresthesia, taste disturbance[Ref]

Other

Common (1% to 10%): Edema, tinnitus
Frequency not reported: Malaise, fatigue[Ref]

Cardiovascular

Frequency not reported: Palpitations[Ref]

Hematologic

Frequency not reported: Neutropenia, thrombocytopenic purpura, leukopenia, agranulocytosis, hemolytic anemia, eosinophilia, hemoglobin decreased, hematocrit decreased[Ref]

Hepatic

Frequency not reported: Liver function tests abnormal, cholestatic jaundice[Ref]

Renal

Frequency not reported: Renal failure[Ref]

Metabolic

Common (1% to 10%): Anorexia[Ref]

Ocular

Frequency not reported: Vision blurred, visual acuity decreased, temporary vision loss, reversible color vision loss, macular fibrosis, macular edema, perimacular edema, conjunctivitis, iritis[Ref]

Psychiatric

Frequency not reported: Depression, insomnia[Ref]

Genitourinary

Frequency not reported: Nocturia[Ref]

Musculoskeletal

Frequency not reported: Lupus-like syndrome[Ref]

Immunologic

Frequency not reported: Serum sickness-like syndrome

References

1. "Product Information. Meclofenamate Sodium (meclofenamate)." Mylan Pharmaceuticals Inc, Morgantown, WV.

Some side effects of meclofenamate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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