Fesoterodine Side Effects

Medically reviewed by Drugs.com. Last updated on Jun 9, 2024.

Applies to fesoterodine: oral tablet extended release.

Precautions

It is very important that your doctor check your progress at regular visits to see if the medicine is working properly and to check for unwanted effects.

This medicine may cause a serious allergic reaction, called angioedema, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs after using this medicine.

This medicine may increase your risk of having urinary retention (trouble passing urine or not fully emptying the bladder). Check with your doctor if you have a decrease in urine volume, decrease in the frequency of urination, difficulty in passing urine (dribbling), or painful urination.

This medicine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.

Avoid drinking alcohol while you are taking this medicine.

This medicine may cause some people to become dizzy, drowsy, or have blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of fesoterodine

Along with its needed effects, fesoterodine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fesoterodine:

Other side effects of fesoterodine

Some side effects of fesoterodine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to fesoterodine: oral tablet extended release.

General adverse events

Most frequently reported adverse events with a frequency of 4% or greater in adult patients with overactive bladder (OAB) were dry mouth and constipation.

Most frequently reported adverse reactions with a frequency of 2% or great in pediatric patients with neurogenic detrusor overactivity (NDO) were diarrhea, urinary tract infection (UTI), dry mouth, constipation, abdominal pain, nausea, increased weight, and headache.^[Ref]

Cardiovascular

• Uncommon (0.1% to 1%): Tachycardia, palpitations
• Postmarketing reports: Palpitations
• Frequency not reported: Electrocardiogram QT corrected interval prolongation^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Rash, dry skin, pruritus
• Rare (less than 0.1%): Angioedema, urticaria^[Ref]

Gastrointestinal

• Very common (10% or more): Dry mouth (34.6%)
• Common (1% to 10%): Abdominal pain, diarrhea, dyspepsia, constipation, nausea, upper abdominal pain
• Uncommon (0.1% to 1%): Abdominal discomfort, flatulence, gastroesophageal reflux
• Frequency not reported: Diverticulitis, irritable bowel syndrome^[Ref]

Genitourinary

• Common (1% to 10%): Dysuria
• Uncommon (0.1% to 1%): Urinary tract infection, urinary retention (e.g., feeling of residual urine, micturition disorder), urinary hesitation^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Increased alanine aminotransferase (ALT), increased gamma glutamyltransferase (GGT)^[Ref]

Hypersensitivity

• Postmarketing reports: Hypersensitivity reactions (e.g., angioedema with airway obstruction, face edema)^[Ref]

Immunologic

• Common (1% to 10%): Infections^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache
• Uncommon (0.1% to 1%): Dysgeusia, somnolence^[Ref]

Ocular

• Common (1% to 10%): Dry eye
• Uncommon (0.1% to 1%): Blurred vision^[Ref]

Other

• Common (1% to 10%): Increased weight
• Uncommon (0.1% to 1%): Peripheral edema, vertigo, fatigue^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia
• Rare (0.01% to 0.1%): Confusional state^[Ref]

Respiratory

• Common (1% to 10%): Dry throat, Upper respiratory tract infection
• Uncommon (0.1% to 1%): Pharyngolaryngeal pain, cough, nasal dryness^[Ref]

See also:

Further information

Fesoterodine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer