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Fesoterodine (Oral)

fes-oh-TER-oh-deen

Medically reviewed on June 7, 2018

Commonly used brand name(s)

In the U.S.

  • Toviaz

Available Dosage Forms:

  • Tablet, Extended Release

Therapeutic Class: Urinary Antispasmodic

Pharmacologic Class: Antimuscarinic

Uses For fesoterodine

Fesoterodine is used to treat symptoms of an overactive bladder, such as incontinence (loss of bladder control) or a frequent need to urinate.

Fesoterodine is available only with your doctor's prescription.

Before Using fesoterodine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fesoterodine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fesoterodine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of fesoterodine in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fesoterodine in the elderly. However, elderly patients are more likely to have unwanted side effects (eg, constipation, dizziness, dry mouth, upset stomach, or urinary tract infection), or age-related liver or kidney problems, which may require caution in patients receiving fesoterodine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking fesoterodine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using fesoterodine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Potassium

Using fesoterodine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Bupropion
  • Donepezil

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of fesoterodine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Glaucoma, narrow-angle or
  • Myasthenia gravis (severe muscle weakness) or
  • Stomach or bowel problems (eg, severe constipation) or
  • Urinary problems (eg, blockage)—Use with caution. May make these conditions worse.
  • Glaucoma, narrow-angle, uncontrolled or
  • Liver disease, severe or
  • Stomach problems (eg, gastric retention) or
  • Urinary retention—Should not be used in patients with these conditions.
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of fesoterodine

Take fesoterodine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Fesoterodine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Fesoterodine may be taken with or without food.

Swallow the extended-release tablet whole with a full glass of water. Do not split, crush, or chew it.

Dosing

The dose of fesoterodine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of fesoterodine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (extended-release tablets):
    • For bladder problems:
      • Adults—At first, 4 milligrams (mg) once a day. Your doctor may increase your dose as needed and tolerated. However, the dose is usually not more than 8 mg once a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of fesoterodine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using fesoterodine

It is very important that your doctor check your progress at regular visits to see if the medicine is working properly and to check for unwanted effects.

Fesoterodine may cause a serious allergic reaction, called angioedema. This can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs after using fesoterodine.

Fesoterodine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking fesoterodine, since overheating may result in heat stroke.

Avoid drinking alcohol while you are taking fesoterodine.

Fesoterodine may cause some people to become dizzy, drowsy, or have blurred vision. Do not drive or do anything else that could be dangerous until you know how fesoterodine affects you.

Fesoterodine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Fesoterodine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  • Difficulty having a bowel movement
  • dry mouth

Less common

  • Bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • body aches or pain
  • burning feeling while urinating
  • chills
  • cough
  • decrease in frequency of urination
  • decrease in urine volume
  • difficult or painful urination
  • difficulty in breathing
  • difficulty in passing urine (dribbling)
  • dry eyes
  • ear congestion
  • fever
  • frequent urge to urinate
  • headache
  • loss of voice
  • lower back or side pain
  • nasal congestion
  • rapid weight gain
  • runny nose
  • sneezing
  • sore throat
  • tingling of the hands or feet
  • unusual tiredness or weakness
  • unusual weight gain or loss

Incidence not known

  • Blurred vision
  • fast, irregular, pounding, or racing heartbeat or pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Back pain
  • belching
  • dry throat
  • heartburn
  • indigestion
  • nausea
  • rash
  • stomach discomfort, upset, or pain
  • trouble sleeping
  • upper abdominal pain

Incidence not known

  • Dizziness
  • itching skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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