Skip to Content

Ezallor Side Effects

Generic Name: rosuvastatin

Note: This document contains side effect information about rosuvastatin. Some of the dosage forms listed on this page may not apply to the brand name Ezallor.

For the Consumer

Applies to rosuvastatin: oral capsule, oral tablet

Side effects requiring immediate medical attention

Along with its needed effects, rosuvastatin (the active ingredient contained in Ezallor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking rosuvastatin:

More common

  • Difficulty in moving
  • joint pain or swelling
  • muscle pain, cramps, spasms, or stiffness

Less common

  • Blurred vision
  • chest pain or discomfort
  • chest tightness or heaviness
  • difficult, burning, or painful urination
  • dry mouth
  • fast, irregular, pounding, or racing heartbeat or pulse
  • flushed, dry skin
  • fruit-like breath odor
  • increased hunger
  • increased thirst
  • increased urination
  • loss of consciousness
  • muscle tension or tightness
  • nausea
  • slow heartbeat
  • stomachache
  • sweating
  • troubled breathing
  • unexplained weight loss
  • unusual tiredness or weakness
  • vomiting

Rare

  • Dark urine
  • fever

Incidence not known

  • Black, tarry stools
  • bleeding gums
  • bloating
  • bloody urine
  • chills
  • clay-colored stools
  • constipation
  • cough
  • general feeling of tiredness or weakness
  • headache
  • hives, itching, skin rash
  • hoarseness
  • indigestion
  • irritation
  • joint swelling
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  • light-colored stools
  • loss of appetite
  • muscular tenderness, wasting, or weakness
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pinpoint red spots on the skin
  • redness of the skin
  • stomach pain, continuing swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • trouble swallowing
  • unpleasant breath odor
  • unusual bleeding or bruising
  • upper right abdominal pain
  • vomiting of blood
  • yellow eyes or skin

Side effects not requiring immediate medical attention

Some side effects of rosuvastatin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Body aches or pain
  • congestion
  • dry or sore throat
  • runny nose
  • tender, swollen glands in the neck
  • voice changes

Less common

  • Accidental injury
  • accumulation of pus, swollen, red, or tender area of infection near a tooth
  • arm, back, or jaw pain
  • belching
  • bladder pain
  • burning feeling in the chest or stomach
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • diarrhea
  • discouragement
  • dizziness
  • excess air or gas in the stomach or bowels
  • excessive muscle tone
  • fear
  • feeling faint
  • feeling of constant movement of self or surroundings
  • feeling of warmth or heat
  • feeling sad or empty
  • flushing or redness of the skin, especially on the face and neck
  • general feeling of discomfort or illness
  • heartburn
  • lack of appetite
  • lack or loss of strength
  • lightheadedness
  • loss of interest or pleasure
  • neck pain
  • nerve pain
  • nervousness
  • pain or swelling in the arms or legs without any injury
  • pain or tenderness around the eyes and cheekbones
  • passing gas
  • pounding in the ears
  • sensation of spinning
  • shivering
  • sneezing
  • stomach discomfort, tenderness, or upset
  • stuffy nose
  • trouble concentrating
  • trouble sleeping

Incidence not known

  • Confusion
  • forgetfulness
  • memory loss
  • nightmares
  • swelling of the breasts or breast soreness in both females and males
  • unsteadiness or awkwardness
  • weakness in the arms, hands, legs, or feet

For Healthcare Professionals

Applies to rosuvastatin: oral capsule, oral tablet

General

The most frequently reported side effects included headache, myalgia, abdominal pain, asthenia, and nausea.[Ref]

Musculoskeletal

Very common (10% or more): Myalgia (up to 12.7%), arthralgia (10.1%)

Rare (less than 0.1%): Myopathy, rhabdomyolysis, myositis

Frequency not reported: Immune-mediated necrotizing myopathy, tendon disorders, creatine phosphokinase increased[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain, nausea, constipation

Rare (less than 0.1%): Pancreatitis

Frequency not reported: Diarrhea[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness

Very rare (less than 0.01%): Polyneuropathy, memory loss

Postmarketing reports: Cognitive impairment, forgetfulness, amnesia, memory impairment, peripheral neuropathy[Ref]

Hepatic

Rare (0.01% to 0.1%): Hepatic transaminases/enzymes increased

Very rare (less than 0.01%): Jaundice, hepatitis

Frequency not reported: Bilirubin increased

Postmarketing reports: Fatal hepatic failure, nonfatal hepatic failure[Ref]

Dermatologic

Uncommon (0.1% to 1%): Rash, pruritus, urticaria

Rare (less than 0.1%): Angioedema

Frequency not reported: Stevens-Johnson syndrome[Ref]

Renal

Frequency not reported: Acute renal failure[Ref]

Genitourinary

Very rare (less than 0.01%): Hematuria

Frequency not reported: Proteinuria, myoglobinuria, sexual dysfunction[Ref]

Other

Common (1% to 10%): Asthenia

Frequency not reported: Edema, glutamyl transpeptidase increased, alkaline phosphatase increased[Ref]

Respiratory

Frequency not reported: Cough, dyspnea, interstitial lung disease[Ref]

Psychiatric

Frequency not reported: Confusion, depression, insomnia, nightmares, sleep disorders/disturbances[Ref]

Endocrine

Very rare (less than 0.01%): Gynecomastia

Frequency not reported: Thyroid function abnormalities[Ref]

Metabolic

Common (1% to 10%): Diabetes mellitus

Frequency not reported: Glucose elevated, HbA1c increased[Ref]

Hematologic

Rare (less than 0.1%): Thrombocytopenia[Ref]

Hypersensitivity

Rare (less than 0.1%): Hypersensitivity reaction[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Crestor (rosuvastatin)." AstraZeneca Pharma Inc, Mississauga, ON.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.